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1.发明公开SYSTEM AND METHODS OF DETECTING AND DEMONSTRATING ULTRAVIOLET DAMAGE TO HAIR VIA EVALUATION OF PROTEIN FRAGMENTS 审中-公开系统及方法评价蛋白片段的厘定和观点UV毛发受损
公开(公告)号：EP3155435A1
公开(公告)日：2017-04-19
申请号：EP15729695.5
申请日：2015-06-03
发明人： DAVIS, Michael, Glenn , FLAGLER, Michael, Joseph , MARSH, Jennifer, Mary , SUN, Yiping , SHAUDHARY, Tanuja
IPC分类号： G01N33/68
CPC分类号： G01N33/6851 , G01N2333/4727 , G01N2440/10 , G01N2500/20 , G01N2560/00 , G01N2570/00 , G01N2800/40
摘要： The present invention is directed to a method to measure ultraviolet or copper damage of hair comprising: eluting a protein fragment from a hair sample with an aqueous solution; extracting the proteins using a solvent; analyzing the protein fragment samples with MALDI-MS; resulting in protein fragment results; identifying presence of a marker protein fragment and identifying what the fragment is by indentifying the amino acid sequence using high resolution Orbitrap -MS wherein the protein fragment is a protein fragment of S100A3.
摘要翻译： 本发明涉及到测量的头发紫外线或铜损害的方法，包括：从头发样品与wässrige溶液洗脱的蛋白质片段; 提取用溶剂中的蛋白质; 分析与MALDI-MS的蛋白片段的样品; 导致蛋白片段的结果; 识别标记蛋白质片段的存在和识别该片段是通过使用高分辨率的Orbitrap MS worin的蛋白片段是S100A3的蛋白质片段蔡作馨的氨基酸序列的内容。
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公开(公告)号：EP3448355A1
公开(公告)日：2019-03-06
申请号：EP17734874.5
申请日：2017-04-28
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3.发明公开METHOD OF DETECTING AND DEMONSTRATING HEAT DAMAGE TO HAIR VIA EVALUATION OF PEPTIDES 审中-公开一种通过评估肽检测和热损伤的显示头发
公开(公告)号：EP3155437A1
公开(公告)日：2017-04-19
申请号：EP15731160.6
申请日：2015-06-03
发明人： WALKER, Ron , SUN, Yiping , DAVIS, Michael, Glenn , WASHINGTON, Randy, Purnell , BEGLINGER, Katherine, Mae , DAVIS, Stephanie, Lee
IPC分类号： G01N33/68
CPC分类号： H01J49/164 , G01N33/6851 , H01J49/0027
摘要： A method to measure heat damage of keratin fibers comprising eluting a peptide from a hair sample with an aqueous solution; extracting the peptide using a suitable solvent sample; analyzing the peptide samples with MALDI-MS; resulting in peptide results; identifying presence of a marker peptide and identifying the m/z ratio for the peptide.
摘要翻译： 的方法，以测量角蛋白纤维包括从头发样品与wässrige溶液洗脱的肽的热损伤; 提取使用合适的溶剂样品的肽; 分析与MALDI-MS的肽样品; 导致肽的结果; 识别标记肽的存在和鉴定对于肽的m / z比。
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4.发明公开
公开(公告)号：EP2572201A1
公开(公告)日：2013-03-27
申请号：EP11721690.3
申请日：2011-05-17
IPC分类号： G01N33/68
CPC分类号： G01N33/4833 , G01N33/6824 , G01N33/6839 , G01N33/6848 , G01N33/6851 , G01N2333/4742 , H01J49/0036
摘要： Embodiments of a method for demonstrating type and/or source of hair damage comprises extracting protein fragments from a hair sample with an aqueous solution, testing the resulting protein fragments with the MALDI-MS test, and then either comparing the results between a damaged sample and an undamaged sample or comparing the results between a damaged sample and a list of known marker protein fragments to identify the type and/or source of the damage.
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5.发明公开METHODS OF DETECTING AND DEMONSTRATING HAIR DAMAGE VIA DETECTION OF PROTEIN LOSS 审中-公开评定程序和头发受损的看法由蛋白缺失的检测
公开(公告)号：EP2572200A1
公开(公告)日：2013-03-27
申请号：EP11721689.5
申请日：2011-05-17
IPC分类号： G01N33/68
CPC分类号： G01N33/6827 , G01N33/6839 , G01N2333/4742
摘要： Embodiments of a method for demonstrating hair damage comprises eluting protein fragments from a hair sample with an aqueous solution, adding a protein indicating reagent to the aqueous solution to provide a visual indicator corresponding to an amount of protein fragments eluted, and comparing the visual indicator to a scale to determine an amount of eluted protein fragments present in the aqueous solution.
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