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1.发明授权A NONINVASIVE METHOD FOR MEASURING HISTAMINE FROM SKIN AS AN OBJECTIVE MEASURMENT OF ITCH 有权FROM AS LENSES瘙痒测量皮肤测量组胺的非侵入性方法
公开(公告)号：EP2478376B1
公开(公告)日：2015-06-17
申请号：EP10755273.9
申请日：2010-09-09
发明人： SCHWARTZ, James, Robert , KERR, Kathleen, Marie , DOYLE, Patricia, West , WEHMEYER, Kenneth, Robert , BURT, Thomas, Massey , FIENO, Angela, Marie , WIMALASENA, Rohan, Lalith , FADAYEL, Gina, Marie
CPC分类号： G01N33/6881 , G01N2001/2833 , G01N2001/4061
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公开(公告)号：EP3996666A1
公开(公告)日：2022-05-18
申请号：EP19745884.7
申请日：2019-07-09
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3.发明公开A NONINVASIVE METHOD FOR MEASURING HISTAMINE FROM SKIN AS AN OBJECTIVE MEASURMENT OF ITCH 有权FROM AS LENSES瘙痒测量皮肤测量组胺的非侵入性方法
公开(公告)号：EP2478376A1
公开(公告)日：2012-07-25
申请号：EP10755273.9
申请日：2010-09-09
发明人： SCHWARTZ, James, Robert , KERR, Kathleen, Marie , DOYLE, Patricia, West , WEHMEYER, Kenneth, Robert , BURT, Thomas, Massey , FIENO, Angela, Marie , WIMALASENA, Rohan, Lalith , FADAYEL, Gina, Marie
CPC分类号： G01N33/6881 , G01N2001/2833 , G01N2001/4061
摘要： A method for measuring of histamine in an epidermis comprising applying an adhesive article to an epithelium of a mammal; allowing for adherence of epithelial cells to the adhesive article; removing the adhesive article from the epithelium of the mammal; preparing the adhesive article using standard laboratory methods for extraction; extracting histamine from the epithelial cells adhered to said adhesive article; measuring histamine from the epithelial cells adhered to said adhesive article; determining the amount of histamine in the epithelial cells as compared to a baseline sample. Further, a method of objectively measuring the perception of itch in mammals and wherein there is a reduction in histamine from a baseline level which is directly proportional to a reduction in an itch perception.
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公开(公告)号：EP3793510A1
公开(公告)日：2021-03-24
申请号：EP19732773.7
申请日：2019-05-15
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公开(公告)号：EP3302407A1
公开(公告)日：2018-04-11
申请号：EP16727115.4
申请日：2016-05-26
发明人： SCHWARTZ, James, Robert , HENRY, James, Patrick , KERR, Kathleen, Marie , WEHMEYER, Kenneth, Robert , LI, Lijuan , MIZOGUCHI, Haruko
CPC分类号： A61K8/58 , A61K8/27 , A61K2800/522 , A61K2800/58 , A61Q5/002 , A61Q5/006 , A61Q5/02 , A61Q5/12
摘要： A method of improving the health of hair emerging from a scalp comprising a reduction of oxidative stress in the scalp by application of a composition resulting in reduction in oxidative stress in pre-emergent hair as demonstrated by reduced oxidative stress in emergent hair.
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公开(公告)号：EP3377027A1
公开(公告)日：2018-09-26
申请号：EP16727114.7
申请日：2016-05-26
发明人： SCHWARTZ, James, Robert , HENRY, James, Patrick , FLAGLER, Michael, Joseph , PAGE, Steven, Hardy , KERR, Kathleen, Marie , WEHMEYER, Kenneth, Robert , LI, Lijuan , REDMAN-FUREY, Nancy, Lee
CPC分类号： A61K8/58 , A61K8/27 , A61K2800/40 , A61K2800/522 , A61Q5/002 , A61Q5/006 , A61Q5/02
摘要： A method of improving the health of hair emerging from a scalp comprising application of a composition to reduce oxidative stress in the scalp causing reduced oxidative stress in pre-emergent hair resulting in healthier emergent hair having reduced water absorption and reduced surface energy
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7.发明公开A NONINVASIVE METHOD FOR MEASURING OXIDATIVE STRESS AND OXIDATIVE DAMAGE FROM SKIN 审中-公开耐腐蚀VERFAHREN ZUR MESSUNG VON氧化剂应力UND OIAIDATIVERSCHÄDIGUNGDER HAUT
公开(公告)号：EP2972324A1
公开(公告)日：2016-01-20
申请号：EP14717367.8
申请日：2014-03-14
发明人： KERR, Kathleen, Marie , FIENO, Angela, Marie , WEHMEYER, Kenneth, Robert , LI, Lijuan , SCHWARTZ, James, Robert , GRANT, Raymond, Alan
IPC分类号： G01N33/50
摘要： A noninvasive method for diagnosing skin health in a subject comprising collecting a skin sample/epithelial cell sample from the subject; detecting a level of one or more biomarkers selected from the group consisting of Myeloperoxidase and oxidized lipids in the epithelial cell sample/skin cell sample; diagnosing the subject as having oxidative stress and/or oxidative damage based on the level of a detected biomarker. Further, a noninvasive method for evaluating the efficacy of products for skin health.
摘要翻译： 用于诊断受试者皮肤健康的非侵入性方法，包括从受试者收集皮肤样品/上皮细胞样品; 检测在上皮细胞样品/皮肤细胞样品中选自由髓过氧化物酶和氧化脂质组成的组中的一种或多种生物标志物的水平; 基于检测到的生物标志物的水平将受试者诊断为具有氧化应激和/或氧化损伤。 此外，用于评估产品对皮肤健康的功效的非侵入性方法。
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公开(公告)号：EP4262729A1
公开(公告)日：2023-10-25
申请号：EP21840370.7
申请日：2021-12-15
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公开(公告)号：EP2972324B1
公开(公告)日：2020-04-22
申请号：EP14717367.8
申请日：2014-03-14
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