公开(公告)号：EP3612189A1

公开(公告)日：2020-02-26

申请号：EP18734873.5

申请日：2018-05-31

申请人： The University Of Leeds ,  The University of York

发明人： LEONOV, German ,  WHITE, Simon ,  STOCKLEY, Peter ,  PATEL, Nikesh ,  WROBLEWSKI, Emma ,  MASKELL, Dan ,  TWAROCK, Reidun ,  BINGHAM, Richard ,  WEISS, Eva ,  DYKEMAN, Eric

IPC分类号： A61K31/7088 ,  C12N15/113

公开(公告)号：EP1560928A2

公开(公告)日：2005-08-10

申请号：EP03778490.7

申请日：2003-11-05

申请人： THE UNIVERSITY OF LEEDS

发明人： STOCKLEY, Peter ,  ADAMS, Christopher ,  BUNKA, David ,  RAMBARAN, Roma ,  PHILLIPS, Simon ,  RADFORD, Sheena

IPC分类号： C12Q1/68

CPC分类号： C12N15/115 ,  C12N2310/16 ,  C12N2310/3517

摘要： The present invention relates to novel nucleic acid molecules or ligands or aptamers with affinities for specific target molecules, and uses of such molecules. The target molecules are fibrillar proteins in all forms of the protein that is to say its monomeric, pre-fibrillar, protofibrillar and mature fibrillar forms. The molecules of the present invention are therefore useful as diagnostic or therapeutic or screening agents, or as potential lead compounds for rationalised drug design.

公开(公告)号：EP3041480A1

公开(公告)日：2016-07-13

申请号：EP14772171.6

申请日：2014-09-05

申请人： The University of York ,  University of Leeds ,  University Of Helsinki

发明人： TWAROCK, Reidun ,  DYKEMAN, Eric ,  STOCKLEY, Peter ,  WHITE, Simon ,  BARKER, Amy ,  PATEL, Nikesh ,  BUTCHER, Sarah ,  SHAKEEL, Shabih ,  HARRIS, Mark ,  STEWART, Hazel

IPC分类号： A61K31/7088 ,  C12N15/115

CPC分类号： C12N15/115 ,  A01N57/16 ,  A61K31/7088 ,  A61K31/7105 ,  C12N15/1048 ,  C12N15/1131 ,  C12N15/8283 ,  C12N2310/13 ,  C12N2310/16 ,  C12N2310/531 ,  C12N2320/31 ,  C12N2330/31 ,  C12Q2600/136 ,  G01N33/5308

摘要： The disclosure relates to anti-viral agents that mimic or inhibit packaging singles of RNA viruses that function in viral capsid formation and their use in the control of viral infection.

摘要翻译： 本公开涉及模拟或抑制在病毒衣壳形成中起作用的RNA病毒包装单体的抗病毒剂及其在控制病毒感染中的用途。