公开(公告)号：EP1145000B8

公开(公告)日：2005-09-14

申请号：EP00973899.8

申请日：2000-10-27

申请人： Therasense, Inc.

发明人： LIAMOS, Charles, T. ,  FELDMAN, Benjamin, J. ,  FUNDERBURK, Jeffery, V. ,  KRISHNAN, Rajesh ,  PLANTE, Phillip, J. ,  VIVOLO, Joseph, A. ,  JIN, Robert, Y. ,  CLOUD, Michael, S. ,  COLMAN, Fredric, C.

IPC分类号： G01N33/487 ,  G01N33/543 ,  G01N27/42

CPC分类号： G01N27/3272 ,  Y10S439/909

摘要： A small volume sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector. In one embodiment, the sensor determines the concentration of the analyte by discharging an amount of charge into the sample, determining the time needed to discharge the charge, and determining the current used to electrolyze a portion of the analyte using the amount of charge and the amount of time.

摘要翻译： 小体积传感器以及制造方法，用于使用诸如库仑法，电流分析法和电位滴定法之类的技术来测定诸如血液或血清的生物流体中诸如葡萄糖或乳酸盐的分析物的浓度。 传感器包括工作电极和反电极，并且可以包括插入监测迹线以确定传感器在连接器中的正确定位。 在一个实施例中，传感器通过将一定量的电荷释放到样品中来确定分析物的浓度，确定释放电荷所需的时间，并且使用电荷量来确定用于电解一部分分析物的电流，并且 多少时间。

公开(公告)号：EP1145000B1

公开(公告)日：2005-05-11

申请号：EP00973899.8

申请日：2000-10-27

申请人： Therasense, Inc.

发明人： LIAMOS, Charles, T. ,  FELDMAN, Benjamin, J. ,  FUNDERBURK, Jeffery, V. ,  KRISHNAN, Rajesh ,  PLANTE, Phillip, J. ,  VIVOLO, Joseph, A. ,  JIN, Robert, Y. ,  CLOUD, Michael, S. ,  COLMAN, Fredric, C.

IPC分类号： G01N33/487 ,  G01N33/543 ,  G01N27/42

CPC分类号： G01N27/3272 ,  Y10S439/909

摘要： A small volume sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector. In one embodiment, the sensor determines the concentration of the analyte by discharging an amount of charge into the sample, determining the time needed to discharge the charge, and determining the current used to electrolyze a portion of the analyte using the amount of charge and the amount of time.

公开(公告)号：EP1145000A1

公开(公告)日：2001-10-17

申请号：EP00973899.8

申请日：2000-10-27

申请人： Therasense, Inc.

发明人： LIAMOS, Charles, T. ,  FELDMAN, Benjamin, J. ,  FUNDERBURK, Jeffery, V. ,  KRISHNAN, Rajesh ,  PLANTE, Phillip, J. ,  VIVOLO, Joseph, A. ,  JIN, Robert, Y. ,  CLOUD, Michael, S. ,  COLMAN, Fredric, C.

IPC分类号： G01N33/487 ,  G01N33/543 ,  G01N27/42

CPC分类号： G01N27/3272 ,  Y10S439/909

摘要： A small volume sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector. In one embodiment, the sensor determines the concentration of the analyte by discharging an amount of charge into the sample, determining the time needed to discharge the charge, and determining the current used to electrolyze a portion of the analyte using the amount of charge and the amount of time.