公开(公告)号：EP3933412A1

公开(公告)日：2022-01-05

申请号：EP20767115.7

申请日：2020-02-19

申请人： Toppan Printing Co., Ltd.

发明人： GOTO, Keisuke ,  MAKINO, Yoichi ,  SUZUKI, Yuta

IPC分类号： G01N37/00 ,  C12M1/00 ,  G01N35/08

摘要： A microfluidic device (1) including: a microwell array (30) having a plurality of microwells; and a cover member (20) facing the microwell array (30) with a gap therebetween, wherein a flow path is provided between the microwell array (30) and the cover member (20), and a surface (20a) of the cover member (20) facing the microwell array (30) has an arithmetic average roughness Ra of 70 nm or less, and a sample analysis method using the microfluidic device (1).

公开(公告)号：EP4235146A3

公开(公告)日：2023-09-20

申请号：EP23161319.1

申请日：2018-03-13

申请人： Toppan Printing Co., Ltd.

发明人： NAGAHARA, Misaki ,  MAKINO, Yoichi ,  HOSHINO, Akihiro ,  HIRASE, Takumi ,  KUNITOMI, Tomoko ,  GOTO, Keisuke ,  HORIUCHI, Yosuke

IPC分类号： G01N37/00 ,  G01N21/64 ,  B01L3/00 ,  G01N15/06 ,  G01N21/03 ,  G01N15/00

摘要： An analysis device is provided for detecting a biochemical reaction by using a detector. The device includes a well array in which a plurality of wells are formed. Each of the wells has an aspect ratio of 1 or more as calculated by the following Formula (1): Aspect ratio = Depth of each well / Diameter of largest circle among circles included in a region enclosed by a rim of each well... Formula (1)

公开(公告)号：EP3933411A1

公开(公告)日：2022-01-05

申请号：EP20763053.4

申请日：2020-02-19

申请人： Toppan Printing Co., Ltd.

发明人： GOTO, Keisuke ,  MAKINO, Yoichi

IPC分类号： G01N37/00 ,  C12M1/00 ,  C12M1/34 ,  G01N35/08 ,  G01N35/10

摘要： There is provided a microfluidic device (1) including a flow path (35), and one or more droplet holders (11) connected to the flow path (35). In the microfluidic device (1), the flow path (35) has a height of more than 0 µm and 30 µm or less. There is also provided a sample analysis method that uses the microfluidic device (1). The method includes introducing a sample-containing aqueous solution into the flow path and allowing the droplet holders to accommodate the aqueous solution, introducing a sealant into the flow path for replacement with the aqueous solution present in the flow path and encapsulating the aqueous solution in the droplet holders, causing a reaction in the droplet holders and generating signals for detection, and detecting the signals.

公开(公告)号：EP4235146A2

公开(公告)日：2023-08-30

申请号：EP23161319.1

申请日：2018-03-13

申请人： Toppan Printing Co., Ltd.

发明人： NAGAHARA, Misaki ,  MAKINO, Yoichi ,  HOSHINO, Akihiro ,  HIRASE, Takumi ,  KUNITOMI, Tomoko ,  GOTO, Keisuke ,  HORIUCHI, Yosuke

IPC分类号： G01N15/06

摘要： An analysis device is provided for detecting a biochemical reaction by using a detector. The device includes a well array in which a plurality of wells are formed. Each of the wells has an aspect ratio of 1 or more as calculated by the following Formula (1): Aspect ratio = Depth of each well / Diameter of largest circle among circles included in a region enclosed by a rim of each well... Formula (1)