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公开(公告)号：EP4235146A2
公开(公告)日：2023-08-30
申请号：EP23161319.1
申请日：2018-03-13
Applicant: Toppan Printing Co., Ltd.
Inventor： NAGAHARA, Misaki , MAKINO, Yoichi , HOSHINO, Akihiro , HIRASE, Takumi , KUNITOMI, Tomoko , GOTO, Keisuke , HORIUCHI, Yosuke
IPC: G01N15/06
Abstract: An analysis device is provided for detecting a biochemical reaction by using a detector. The device includes a well array in which a plurality of wells are formed. Each of the wells has an aspect ratio of 1 or more as calculated by the following Formula (1): Aspect ratio = Depth of each well / Diameter of largest circle among circles included in a region enclosed by a rim of each well... Formula (1)
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Patent Agency Ranking
公开(公告)号：EP2873976A1
公开(公告)日：2015-05-20
申请号：EP13814000.9
申请日：2013-07-02
Applicant: Toppan Printing Co., Ltd. , Tokyo Institute of Technology
Inventor： HIRASE, Takumi , NAKAYAMA, Masato , HANDA, Hiroshi , SAKAMOTO, Satoshi , NAITO, Yasuyuki
IPC: G01N33/543 , G01N21/64
CPC classification number: G01N33/54326 , G01N21/6428 , G01N21/645
Abstract: A detection system of a test substance (10), includes: a magnetic body (2) that is modified by a first substance (3) capable of being bound to the test substance (10) at a first binding site of the test substance; a marker (4) that is modified by a second substance (3) capable of being bound to the test substance (10) at a second binding site of the test substance (10), the second binding site being a different site from the first binding site; a development medium (20) that has a flow passage (24) into which liquid, in which the magnetic body (2) and the marker (4) is dispersed, flows by a capillary phenomenon, the development medium having a detection position for detecting the marker (4) in a portion of the flow passage (24), the development medium having light transparency at least in the detection position; and a magnetic force generating portion (30) that is equipped in the development medium (20) in order to hold the magnetic body (2) in a portion of the flow passage (24).
Abstract translation: 测试物质（10）的检测系统包括：被测物质的第一结合位点被能够与测试物质（10）结合的第一物质（3）改性的磁体（2）; 由能够在被检物质（10）的第二结合位点与被检物质（10）结合的第二物质（3）修饰的标记物（4），所述第二结合位点是与所述第一物质 结合位点; 具有流路（24）的显影介质（20），其中分散有磁性体（2）和标记物（4）的液体通过毛细管现象流动，所述显影介质具有检测位置 在所述流路（24）的一部分中的所述标记（4），所述显影介质至少在所述检测位置具有透光性; 以及设置在显影介质（20）中以将磁体（2）保持在流路（24）的一部分中的磁力产生部分（30）。
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公开(公告)号：EP4235146A3
公开(公告)日：2023-09-20
申请号：EP23161319.1
申请日：2018-03-13
Applicant: Toppan Printing Co., Ltd.
Inventor： NAGAHARA, Misaki , MAKINO, Yoichi , HOSHINO, Akihiro , HIRASE, Takumi , KUNITOMI, Tomoko , GOTO, Keisuke , HORIUCHI, Yosuke
Abstract: An analysis device is provided for detecting a biochemical reaction by using a detector. The device includes a well array in which a plurality of wells are formed. Each of the wells has an aspect ratio of 1 or more as calculated by the following Formula (1): Aspect ratio = Depth of each well / Diameter of largest circle among circles included in a region enclosed by a rim of each well... Formula (1)
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公开(公告)号：EP3460474A1
公开(公告)日：2019-03-27
申请号：EP17799494.4
申请日：2017-05-19
Applicant: Toppan Printing Co., Ltd.
Inventor： MAKINO, Yoichi , HIRASE, Takumi , ARAI, Noriaki , NOJI, Hiroyuki
IPC: G01N33/543 , C12Q1/68 , G01N33/58
Abstract: A method for detecting a target molecule includes a step of preparing a plurality of types of specific binding substances that are labeled with a plurality of nucleic acid fragments each having a labeling substance that generates a fluorescence signal of a different fluorescence wavelength, and that each recognize a different epitope, and preparing a plurality of types of first target molecules; a step of binding the plurality of types of specific binding substances to the plurality of types of first target molecules; a step of respectively detecting the plurality of types of specific binding substances; and a step of determining the plurality of types of first target molecules by a plurality of the fluorescence signals corresponding to the plurality of types of specific binding substances.
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公开(公告)号：EP4047368A1
公开(公告)日：2022-08-24
申请号：EP22160097.6
申请日：2017-05-19
Applicant: Toppan Printing Co., Ltd.
Inventor： MAKINO, Yoichi , HIRASE, Takumi , ARAI, Noriaki , NOJI, Hiroyuki
IPC: G01N33/543 , C12Q1/68 , G01N33/58
Abstract: A method for detecting a target molecule includes a step of preparing a plurality of types of specific binding substances that are labeled with a plurality of nucleic acid fragments each having a labeling substance that generates a fluorescence signal of a different fluorescence wavelength, and that each recognize a different epitope, and preparing a plurality of types of first target molecules; a step of binding the plurality of types of specific binding substances to the plurality of types of first target molecules; a step of respectively detecting the plurality of types of specific binding substances; and a step of determining the plurality of types of first target molecules by a plurality of the fluorescence signals corresponding to the plurality of types of specific binding substances.
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公开(公告)号：EP3712275A1
公开(公告)日：2020-09-23
申请号：EP18879365.7
申请日：2018-11-15
Applicant: Toppan Printing Co., Ltd.
Inventor： HIRASE, Takumi , MAKINO, Yoichi , HORIUCHI, Yosuke
Abstract: A method for detecting a target molecule includes the steps of: providing a fluid device having a substrate and a well array disposed on the substrate; supplying a dispersion liquid of a structure including a target molecule into the well array of the fluid device, and introducing the structure into wells of the well array; supplying a sealing solution into the well array, forming a layer of the sealing solution on the dispersion liquid introduced in the wells, and sealing the dispersion liquid in the wells; extracting the target molecule from the structure; and detecting the target molecule.
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