专利检索 ap:("Troponwerke GmbH & Co. KG" OR "BAYER AG") AND inv:"VAN DER STAAY, Franz-Josef" 第 1 页

1.

发明公开
USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION 失效
标题翻译：膦酸酯的用于治疗脑断电和抑郁症

公开(公告)号：EP0896540A1

公开(公告)日：1999-02-17

申请号：EP97920431.0

申请日：1997-04-17

申请人： Troponwerke GmbH & Co. KG , BAYER AG

发明人： MAURER, Fritz , SCHMIDT, Bernard , LENSKY, Stephan , VAN DER STAAY, Franz-Josef , FANELLI, Richard, Joseph , BRITELLI, David, Ross

IPC分类号： A61K31 , A61P25 , C07F9

CPC分类号： C07F9/4006

摘要： The present invention relates to the use of phosphonic acid esters for the treatment and prevention of functional disorders of the brain and depression.

2.

发明公开
NEUE 2-AMINOCARBONYL-5(2H)-ISOXAZOLONE ALS LIGANDEN EINER DFP-BINDUNGSSTELLE ZUR BEHANDLUNG VON ZNS-KRANKHEITEN 审中-公开
标题翻译： NEW 2-氨基羰基 - 5（2H） - 异恶唑酮作为配体甲DFP结合位点CNS疾病治疗的

公开(公告)号：EP1087950A1

公开(公告)日：2001-04-04

申请号：EP99929179.2

申请日：1999-06-11

申请人： BAYER AG

发明人： LENSKY, Stephan , RIEDL, Bernd , FÜRSTNER, Chantal , ERGÜDEN, Jens , BÖSS, Frank , SCHMIDT, Bernard , VAN DER STAAY, Franz-Josef , SCHRÖDER, Werner , SCHUHMACHER, Joachim , SCHMIDT, Delf

IPC分类号： C07D261/12 , C07D413/06 , A61K31/42

CPC分类号： C07D413/06 , C07D261/12

摘要： The invention relates to new 2-aminocarbonyl-5(2H)-isoxazolones used as selective ligands of a high-affinity binding site of diisopropyl-fluorophosphate (DFP) on brain membranes, for prophylaxis and treatment of diseases of the central nervous system, especially cognitive disorders, depression, schizophrenia and anxiety.