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公开(公告)号:EP2986644A4
公开(公告)日:2016-11-23
申请号:EP14785790
申请日:2014-04-15
发明人: HAYNES BARTON F , LIAO HUA-XIN , DANISHEFSKY SAMUEL , PARK PETER , SODROSKI JOSEPH , AUSSEDAT BAPTISTE , VOHRA YUSUF
CPC分类号: A61K39/12 , A61K2039/545 , A61K2039/55566 , C07K14/001 , C07K14/005 , C07K14/162 , C12N2740/16034 , C12N2740/16134 , G01N33/56988 , G01N2333/16
摘要: The present invention relates, in general, to human immunodeficiency virus (HIV), and, in particular, to a vaccine for HIV-1, comprising synthetic V3 glycopeptides, and to methods of making and using same.
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公开(公告)号:EP2912055A4
公开(公告)日:2016-06-08
申请号:EP13848800
申请日:2013-10-28
发明人: HAYNES BARTON F , LIAO HUA-XIN , ALAM S MUNIR , DANISHEFSKY SAMUEL , AUSSEDAT BAPTISTE , PARK PETER K , VOHRA YUSUF , SODROSKI JOSEPH
IPC分类号: C07K14/155 , A61K39/12 , A61K39/21 , C07K14/005 , C07K16/10 , C12N7/00
CPC分类号: A61K39/21 , A61K39/12 , C07K14/005 , C07K16/1063 , C07K2317/34 , C07K2317/76 , C12N7/00 , C12N2740/16122 , C12N2740/16134
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公开(公告)号:EP2136835A4
公开(公告)日:2011-06-08
申请号:EP08742681
申请日:2008-04-10
发明人: HAYNES BARTON F , LIAO HUA-XIN , MA BEN-JIANG , SODROSKI JOSEPH
IPC分类号: A61K39/00
CPC分类号: A61K39/21 , A61K39/12 , C12N2740/16034
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公开(公告)号:EP2788026A4
公开(公告)日:2015-08-05
申请号:EP12854613
申请日:2012-12-05
申请人: UNIV DUKE , US GOVERNMENT , UNIV NEW YORK
CPC分类号: C07K14/005 , A61K39/12 , A61K39/21 , C07K14/162 , C07K16/1063 , C07K2317/34 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C12N2710/24043 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134
摘要: The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same.
摘要翻译: 本发明一般涉及人类免疫缺陷病毒(HIV),特别涉及用于HIV-1的疫苗及其制备和使用方法。
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公开(公告)号:EP2694542A4
公开(公告)日:2014-10-08
申请号:EP12768353
申请日:2012-04-09
申请人: UNIV DUKE , US GOVERNMENT
发明人: HAYNES BARTON F , LIAO HUA-XIN , MOODY M ANTHONY , TOMARAS GEORGIA D , KIM JEROME , MICHAEL NELSON
CPC分类号: C07K16/087
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公开(公告)号:EP2331133A4
公开(公告)日:2012-09-12
申请号:EP09811854
申请日:2009-09-08
申请人: UNIV DUKE
发明人: HAYNES BARTON F , MOODY M ANTHONY , LIAO HUA-XIN
IPC分类号: A61K39/395 , A61P31/18 , C07K16/28 , C07K16/44
CPC分类号: C07K16/44 , C07K16/28 , C07K2317/21 , C07K2317/76
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7.METHOD OF INDUCING THE PRODUCTION OF PROTECTIVE ANTI-HIV-1 ANTIBODIES 审中-公开
标题翻译: 方法对于确保保护性抗体对HIV-1的生产公开(公告)号:EP2539365A4
公开(公告)日:2015-03-25
申请号:EP11747821
申请日:2011-02-25
申请人: UNIV DUKE
发明人: HAYNES BARTON F , LIAO HUA-XIN , TOMARAS GEORGIA , KEPLER THOMAS B , HWANG KWAN-KI , ALAM S MUNIR , LIU YANG , HOLL T MATT , YANG GUANG , KELSOE GARNETT , BONSIGNORI MATTIA
CPC分类号: A61K39/21 , A61K39/0005 , A61K39/0258 , A61K2039/53 , A61K2039/58 , C07K16/1063 , C12N2740/16034 , C12N2740/16134
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8.A BROADLY NEUTRALIZING HUMAN ANTIBODY THAT RECOGNIZES THE RECEPTOR-BINDING POCKET OF INFLUENZA HEMAGGLUTININ 有权
标题翻译: 与受体的识别与流感血凝素口袋宽的人抗体公开(公告)号:EP2739312A4
公开(公告)日:2014-12-31
申请号:EP12819608
申请日:2012-08-03
发明人: WHITTLE JAMES , HARRISON STEPHEN C , HAYNES BARTON F , LIAO HUA-XIN , MOODY M ANTHONY , KEPLER THOMAS B , SCHMIDT AARON G
CPC分类号: C07K16/1018 , A61K31/713 , A61K38/02 , A61K47/6841 , A61K51/1006 , C07K2299/00 , C07K2317/33 , C07K2317/55 , C07K2317/565 , C07K2317/76
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9.METHOD OF INDUCING NEUTRALIZING ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS 审中-公开
标题翻译: 诱导抗HIV中和抗体的方法公开(公告)号:EP2139516A4
公开(公告)日:2011-06-29
申请号:EP08742782
申请日:2008-04-11
申请人: UNIV DUKE
发明人: HAYNES BARTON F , ALAM S MUNIR , LIAO HUA-XIN
IPC分类号: A61K39/21 , A61K39/385
CPC分类号: A61K39/21 , A61K39/12 , A61K39/385 , A61K47/6911 , A61K2039/545 , A61K2039/55555 , A61K2039/55561 , A61K2039/55566 , A61K2039/55572 , A61K2039/575 , A61K2039/6018 , A61K2039/62 , A61K2039/625 , A61K2039/627 , A61K2039/64 , C07K14/005 , C07K16/1063 , C07K2317/21 , C07K2317/34 , C07K2317/76 , C12N7/00 , C12N2740/15022 , C12N2740/16122 , C12N2740/16134
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10.METHOD OF INDUCING NEUTRALIZING ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS 审中-公开
标题翻译: VERFAHREN ZUR INDUKTION VON NEUTRALISIERENDENANTIKÖRPERNGEGEN DAS HIV-VIRUS公开(公告)号:EP1868651A4
公开(公告)日:2010-10-06
申请号:EP06740904
申请日:2006-04-12
申请人: UNIV DUKE
发明人: LIAO HUA-XIN , ALAM MUNIR S , HAYNES BARTON F
CPC分类号: A61K39/21 , A61K9/127 , A61K39/0005 , A61K39/12 , A61K39/385 , A61K2039/55505 , A61K2039/55555 , A61K2039/55561 , A61K2039/55566 , A61K2039/57 , A61K2039/6018 , C07K14/005 , C07K16/1063 , C07K16/18 , C07K2317/76 , C07K2319/00 , C12N2740/16011 , C12N2740/16111 , C12N2740/16122 , C12N2740/16134
摘要: The present invention relates to a method of inducing the production of anti-HIV antibodies. The method comprises administering at least one liposome-peptide conjugate, wherein the peptide comprises a membrane proximal external region (MPER) epitope.
摘要翻译: 本发明一般涉及人类免疫缺陷病毒(HIV),特别是涉及诱导HIV中和抗体的方法以及适用于这种方法的化合物和组合物。
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