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1.
公开(公告)号:EP2991655A4
公开(公告)日:2017-01-04
申请号:EP14791101
申请日:2014-04-29
发明人: PATEL DINSHAW J , TUSCHL THOMAS , ASCANO MANUEL , WU YANG , LIU YIZHOU , BARCHET WINFRIED , HARTMANN GUNTHER , ZILLINGER THOMAS , JONES ROGER , GAFFNEY BARBARA L , GAO PU
IPC分类号: A61K31/708 , A61K31/7076 , A61K31/7084 , C07F9/6574 , C07H21/00 , C12Q1/48 , G06F19/16 , G06F19/18 , G06K9/00 , G06K9/46
CPC分类号: C07H21/00 , A61K31/522 , A61K47/55 , C07F9/65746 , C12Q1/485 , C12Y207/07 , G01N2500/04 , G01N2500/10 , G06F19/16 , G06F19/18 , G06K9/00147 , G06K9/46
摘要: The invention relates to compositions, methods, kits, and assays related to the use and/or exploitation of isomers of cGAMP as well as the structure of the enzyme cGAS.
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公开(公告)号:EP1883709A4
公开(公告)日:2010-10-13
申请号:EP06752071
申请日:2006-05-01
申请人: UNIV ROCKEFELLER
发明人: LANDGRAF PABLO , TUSCHL THOMAS
IPC分类号: C07H21/02 , A61K48/00 , C07H21/04 , C12N15/113
CPC分类号: C12N15/113 , C12N2310/14 , C12N2330/10
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公开(公告)号:EP3027227A4
公开(公告)日:2018-05-23
申请号:EP14832592
申请日:2014-07-31
发明人: PATEL DINSHAW J , TUSCHL THOMAS , JONES ROGER , HARTMANN GUNTHER , BARCHET WINFRIED , ZILLINGER THOMAS , DENG LIANG , ASCANO MANUEL JR , WANG WEIYI , GAO PU
IPC分类号: A61K48/00
CPC分类号: G06F19/16 , A61K31/352 , A61K31/473 , A61K31/7084 , C07K14/705 , C07K14/7156 , C07K2299/00 , G01N33/68 , G01N2333/52 , G01N2400/00 , G01N2500/04 , G06F19/12
摘要: The present invention provides STING crystals. The present invention also provides STING modulators that interact with sites present in and/or defined by such crystals. The present invention also provides methods of making and using such crystals and modulators. Other aspects and/or features of the present invention will be apparent to those skilled in the art, reading the present specification.
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