摘要:
A catheter shaft (32) carries a coaxial cable (76) which has an inner conductor (120), an inner insulator (122), an outer conductor (124), and an outer insulator (126). The outer conductor (124) is connected to a midpoint (146) of a helical wire coil (140) at a terminal end of the coaxial cable (76) so as to form a dipole antenna (74) having a proximal helical element (144) and a distal helical element (142). A series capacitance (128) is connected between the inner conductor (120) of the coaxial cable (76) and a point (148) on the proximal helical element (144) where a resistive component of the antenna's impedance matches a characteristic impedance of the coaxial cable (76).
摘要:
A method and apparatus for reducing restenosis of a stenotic region of a blood vessel after performing dilation angioplasty treatment is disclosed. The method includes radiating microwave energy from a microwave antenna (52) to kill a medial tissue layer of the blood vessel in the stenotic region. The radiation is applied during or after inflation of dilatation balloon (18) to permanently dilate the stenotic region. When radiation is applied during dilatation of the stenotic region, the dilatation balloon (18) forms a seal against the inner wall surface of the blood vessel to exclude blood in the vessel from contacting the stenotic region. The method preferably further includes cooling the blood circulating in the blood vessel about a shaft of the catheter with cooling fluid circulating within cooling lumens (70, 72) of the catheter and cooling an inner wall surface of the blood vessel in the stenotic region during the application of radiation to the medial cell layer. Finally, the method also preferably includes perfusing blood in the vessel through the catheter (250) across the stenotic region during dilatation of the stenotic region to maintain circulation of blood through the blood vessel during the dilatation of the stenotic region.
摘要:
A thermal therapy catheter (28) includes a catheter shaft (32) having an outer surface (52) that is insertable into a body lumen. The catheter shaft (32) carries an energy-emitting element (74). A multi-lobe balloon (71) is positioned around the outer surface (52) of the catheter shaft (32) adjacent to the energy-emitting element (74), with opposing ends of the multi-lobe balloon (71) being sealingly connected to the catheter shaft (32) to form a chamber between the multi-lobe balloon (71) and the outer surface (52) of the catheter shaft (32). A fluid is circulated between the outer surface (52) of the catheter shaft (32) and the multi-lobe balloon (71) in a defined fluid flow path to firmly contact the wall of the body lumen and thereby conductively cool the body lumen tissue while thermally treating targeted tissue at a depth from the body lumen wall.
摘要:
A thermal therapy method includes inserting a microwave antenna containing applicator (27) into a body cavity such as a urethra (10) adjacent a targeted tissue region such as a prostate (14), energizing the microwave antenna (30), circulating coolant between the microwave antenna, and a wall of the body cavity. The therapy is controlled by decreasing a temperature of the coolant, and continually adjusting coolant temperature based on other parameters. The applicator is maintained at a predetermined temperature set point by adjusting a power level provided to the microwave antenna. In one embodiment involving treatment of the prostate, rectal temperature is monitored, and upon sensing a rectal temperature that exceeds a predetermined threshold, the temperature of the coolant is increased to force a reduction in power provided to the microwave antenna to maintain the applicator at the predetermined temperature set point.
摘要:
A thermal therapy catheter (28) includes a catheter shaft (32) having an outer surface (52) that is insertable into a body lumen. The catheter shaft (32) carries an energy-emitting element (74). A multi-lobe balloon (71) is positioned around the outer surface (52) of the catheter shaft (32) adjacent to the energy-emitting element (74), with opposing ends of the multi-lobe balloon (71) being sealingly connected to the catheter shaft (32) to form a chamber between the multi-lobe balloon (71) and the outer surface (52) of the catheter shaft (32). A fluid is circulated between the outer surface (52) of the catheter shaft (32) and the multi-lobe balloon (71) in a defined fluid flow path to firmly contact the wall of the body lumen and thereby conductively cool the body lumen tissue while thermally treating targeted tissue at a depth from the body lumen wall.
摘要:
A device (28) for prostate treatment is inserted into a prostatic portion (10A) of an urethra (10) and connected to an energy source (37). Energy is delivered to the prostate (14) from the device (28). The amount of energy emitted to prostatic tissue adjacent to a bladder (12) is greater than that emitted to prostatic tissue distant from the bladder (12).
摘要:
A method for treating an individual with diseased prostatic tissue, such as benign prostatic hyperplasia, includes inserting a catheter (28) into a urethra (10) to position a microwave antenna (74) located within the catheter (28) adjacent a prostatic region of the urethra (10). A microwave antenna (74) is then driven within a power range for applying microwave energy substantially continuously to prostatic tissue (96) to heat the prostatic tissue (96) surrounding the microwave antenna (74) at a temperature and for a time period sufficient to cause necrosis of the prostatic tissue (96).