专利检索 ap:("UWM Research Foundation, Inc." OR "The Trustees of Columbia University in the City of New York") AND inv:"COOK, James, M." 第 1 页

1.

发明公开
GABA(A) RECEPTOR MODULATORS AND METHODS TO CONTROL AIRWAY HYPERRESPONSIVENESS AND INFLAMMATION IN ASTHMA 审中-公开

公开(公告)号：EP3500573A1

公开(公告)日：2019-06-26

申请号：EP17758373.9

申请日：2017-08-16

申请人： UWM Research Foundation, Inc. , The Trustees of Columbia University in the City of New York

发明人： ARNOLD, Alexander, E. , STAFFORD, Douglas, C. , COOK, James, M. , EMALA, Charles, W. , FORKUO, Gloria , JAHAN, Rajwana , KODALI, Revathi , LI, Guanguan , STEPHEN, Michael, Rajesh

IPC分类号： C07D487/04 , C07D487/14 , A61K31/5517 , A61P11/00

2.

发明公开
NOVEL GABAA AGONISTS AND METHODS OF USING TO CONTROL AIRWAY HYPERRESPONSIVENESS AND INFLAMMATION IN ASTHMA 审中-公开
标题翻译：新型GABA促进剂和方法用于防治气道高反应和炎症哮喘

公开(公告)号：EP2897963A1

公开(公告)日：2015-07-29

申请号：EP13838190.0

申请日：2013-09-20

申请人： UWM Research Foundation, Inc. , The Trustees of Columbia University in the City of New York

发明人： STAFFORD, Douglas, C. , COOK, James, M. , ARNOLD, Alexander, E. , EMALA, Charles, W. , GALLOS, George , STEPHEN, Michael, Rajesh

IPC分类号： C07D487/14 , A61K31/5517 , A61P11/06 , A61P29/00

CPC分类号： C07D487/22 , C07D487/14

摘要： Novel methods of treating inflammation and airway constriction using GABAergic compounds with reduced benzo-diazepine-like CNS activity are provided. Novel compounds which selectively target alpha-4 and alpha-5 GABAA receptors and methods of using those compounds to treat bronchoconstriction and inflammation are provided herein.

3.

发明公开
IMIDAZOBENZODIAZEPINES FOR TREATMENT OF COGNITIVE AND MOOD SYMPTOMS 审中-实审

公开(公告)号：EP4399211A1

公开(公告)日：2024-07-17

申请号：EP22778167.1

申请日：2022-09-08

申请人： UWM Research Foundation, Inc. , Centre For Addiction And Mental Health

发明人： PREVOT, Thomas, Damien , MARCOTTE, Michael, Jeffrey , SIBILLE, Etienne, Laurent , COOK, James, M. , LI, Guangan , MONDAL, Prithu , MIAN, Md, Yeunus , RASHID, Farjana

IPC分类号： C07D487/04 , A61P25/00 , A61K31/5517

CPC分类号： C07D487/04 , A61P25/00

4.

发明公开
AZA-BETA-CARBOLINES AND METHODS OF USING SAME 审中-公开
标题翻译： AZA-β-LINE卡博和申请流程。

公开(公告)号：EP2307410A1

公开(公告)日：2011-04-13

申请号：EP09751673.6

申请日：2009-05-22

申请人： The UWM Research Foundation, Inc

发明人： COOK, James, M. , VAN LINN, Michael, L. , YIN, Wenyuan

IPC分类号： C07D471/04 , A61K31/437 , A61P25/32

CPC分类号： C07D471/04

摘要： Provided are compounds having the general structure according to Formula (I). Further provided are pharmaceutical compositions comprising these compounds. The invention still further provides methods of treating alcoholism, methods of reducing alcohol intake, methods of treating anhedonia, and methods of treating anxiety using theses compounds or the compositions containing them.