专利检索 ap:("UWM Research Foundation, Inc." OR "The Trustees of Columbia University in the City of New York") AND inv:"EMALA, Charles, W." 第 1 页

1.

发明公开
GABA(A) RECEPTOR MODULATORS AND METHODS TO CONTROL AIRWAY HYPERRESPONSIVENESS AND INFLAMMATION IN ASTHMA 审中-公开

公开(公告)号：EP3500573A1

公开(公告)日：2019-06-26

申请号：EP17758373.9

申请日：2017-08-16

申请人： UWM Research Foundation, Inc. , The Trustees of Columbia University in the City of New York

发明人： ARNOLD, Alexander, E. , STAFFORD, Douglas, C. , COOK, James, M. , EMALA, Charles, W. , FORKUO, Gloria , JAHAN, Rajwana , KODALI, Revathi , LI, Guanguan , STEPHEN, Michael, Rajesh

IPC分类号： C07D487/04 , C07D487/14 , A61K31/5517 , A61P11/00

2.

发明公开
NOVEL GABAA AGONISTS AND METHODS OF USING TO CONTROL AIRWAY HYPERRESPONSIVENESS AND INFLAMMATION IN ASTHMA 审中-公开
标题翻译：新型GABA促进剂和方法用于防治气道高反应和炎症哮喘

公开(公告)号：EP2897963A1

公开(公告)日：2015-07-29

申请号：EP13838190.0

申请日：2013-09-20

申请人： UWM Research Foundation, Inc. , The Trustees of Columbia University in the City of New York

发明人： STAFFORD, Douglas, C. , COOK, James, M. , ARNOLD, Alexander, E. , EMALA, Charles, W. , GALLOS, George , STEPHEN, Michael, Rajesh

IPC分类号： C07D487/14 , A61K31/5517 , A61P11/06 , A61P29/00

CPC分类号： C07D487/22 , C07D487/14

摘要： Novel methods of treating inflammation and airway constriction using GABAergic compounds with reduced benzo-diazepine-like CNS activity are provided. Novel compounds which selectively target alpha-4 and alpha-5 GABAA receptors and methods of using those compounds to treat bronchoconstriction and inflammation are provided herein.