公开(公告)号：EP2668164A1

公开(公告)日：2013-12-04

申请号：EP12706636.3

申请日：2012-01-27

申请人： Université Claude Bernard Lyon I ,  Hospices Civils de Lyon ,  Centre National de la Recherche Scientifique (CNRS) ,  Université Joseph Fourier

发明人： DOLEANS-JORDHEIM, Anne ,  FRENEY, Jean ,  DUMONTET, Charles ,  BOUMENDJEL, Ahcène ,  VERON, Jean-Baptiste ,  WONG, Yung-Sing

IPC分类号： C07D215/06 ,  A61K31/404

CPC分类号： A61K31/4704 ,  A61K31/395 ,  A61K31/431 ,  A61K31/4709 ,  A61K31/473 ,  A61K31/496 ,  A61K31/5383 ,  A61K31/65 ,  A61K31/7048 ,  A61K38/14 ,  A61K45/06 ,  C07D215/06 ,  C07D215/58 ,  C07D401/04 ,  C07D409/04 ,  C12Q1/025 ,  A61K2300/00

摘要： The present invention relates to compounds of formula (I), where R1 and R2, identical or different, are each independently a hydrogen atom or a non-substituted or substituted (C1-C12) alkyl group; R3 is a hydrogen atom or a non-substituted or substituted (C1-C6) alkyl group; R4 is a non-substituted or substituted (C1-C12) alkyl group or an aryl or heteroaryl group, said aryl and heteroaryl groups being non-substituted or substituted; and R5 is a non-substituted or substituted (C1-C12) alkyl group; or R4 and R5 are bonded to one another by a saturated hydrocarbon chain having 3 or 4 carbon atoms, optionally in hydrated form or in the form of a salt that is acceptable for being administered to animals or plants, for the use thereof as a potentiator of the effect of an antimicrobial agent or for the use thereof as an antimicrobial agent.