公开(公告)号：EP3582809A1

公开(公告)日：2019-12-25

申请号：EP18706464.7

申请日：2018-02-15

申请人： Université Grenoble Alpes ,  Centre Hospitalier Universitaire Grenoble Alpes ,  Etablissement Français du Sang

发明人： LE GOUELLEC, Audrey ,  TOUSSAINT, Bertrand ,  LENORMAND, Jean-Luc ,  LAURIN, David ,  MEYNET, Elodie

IPC分类号： A61K39/104 ,  C12N1/20 ,  C12N1/36 ,  C12N15/10 ,  C12N15/78

公开(公告)号：EP3363460A1

公开(公告)日：2018-08-22

申请号：EP17305173.1

申请日：2017-02-16

申请人： Université Grenoble Alpes ,  Centre Hospitalier Universitaire Grenoble ,  Etablissement Français du Sang

发明人： LE GOUELLEC, Audrey ,  TOUSSAINT, Bertrand ,  LENORMAND, Jean-Luc ,  LAURIN, David ,  MEYNET, Elodie

IPC分类号： A61K39/104 ,  C12N1/20 ,  C12N1/36 ,  C12N15/10 ,  C12N15/78

CPC分类号： A61K39/104 ,  A61K2039/522 ,  C12N1/20 ,  C12N1/36 ,  C12N15/78

摘要： The present invention is related to a live-attenuated strain of Pseudomonas for its use as a vaccine, and for use in a method for preventive immunizing and for treating Pseudomonas infection, in particular in patients suffering from cystic fibrosis. Preferably, the live-attenuated strain of Pseudomonas is furthermore treated to become 'killed but metabolically active'.