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公开(公告)号：EP2523595B1
公开(公告)日：2018-08-22
申请号：EP11700172.7
申请日：2011-01-12
申请人： Université de Bordeaux 1 , Centre National de la Recherche Scientifique (CNRS) , Université Bordeaux Segalen , Institut Polytechnique de Bordeaux
发明人： LANG, Jochen , CATARGI, Bogdan , RENAUD, Sylvie , RAOUX, Matthieu , CHARPENTIER, Gilles , BORNAT, Yannick
CPC分类号： A61B5/14532 , A61B5/425 , A61B5/6848 , A61B5/685 , A61B2562/0209 , A61B2562/028 , A61B2562/125 , A61M5/14244 , A61M5/14276 , A61M5/1723 , A61M2005/1726 , A61M2230/201
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2.发明公开CAPTEUR POUR LA MESURE DE L'ACTIVITÉ DES CELLULES BETA-PANCRÉATIQUES OU DES ÎLOTS DE LANGERHANS, FABRICATION ET UTILISATION D'UN TEL CAPTEUR 审中-公开传感器用于测量β细胞胰腺或朗格汉斯群岛，生产和这种传感器的使用活动
公开(公告)号：EP2523595A1
公开(公告)日：2012-11-21
申请号：EP11700172.7
申请日：2011-01-12
申请人： UNIVERSITE DE BORDEAUX I , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , Université Bordeaux Segalen , Institut Polytechnique De Bordeaux
发明人： LANG, Jochen , CATARGI, Bogdan , RENAUD, Sylvie , RAOUX, Matthieu , CHARPENTIER, Gilles , BORNAT, Yannick
CPC分类号： A61B5/14532 , A61B5/425 , A61B5/6848 , A61B5/685 , A61B2562/0209 , A61B2562/028 , A61B2562/125 , A61M5/14244 , A61M5/14276 , A61M5/1723 , A61M2005/1726 , A61M2230/201
摘要： The invention relates to a sensor (2) including: a microelectrode assembly (21); and β-pancreatic cells (23) or islets (230) of Langerhans in culture on the microelectrode assembly (21); characterized in that the microelectrode assembly (21) is designed to measure dynamically, continuously and in real time, electrical signals (V) produced by the β-pancreatic cells (23) or the islets of Langerhans (230) upon physiological activation. The invention also relates to the field of devices that can be implantable in in the body of a patient, and including an insulin dispenser for dispensing an amount of insulin. The invention also relates to a method for manufacturing such a sensor and to such a device and a use of such a sensor.
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