摘要:
The invention relates to an atomic force microscopy probe (SM) including a micromechanical resonator (RMM) and a tip for atomic force microscopy (P1) protruding from said resonator, characterised in that it also comprises a means (EL1) for selectively exciting an oscillation mode of the volume of said resonator (RMM), and in that said tip for atomic force microscopy (P1, P1') protrudes from said resonator substantially in correspondence with a ventral point (PV1) of said volume oscillation mode. The invention also relates to an atomic force microscope including such a probe (SM'), and to an atomic force microscopy method involving the use of such a probe.
摘要:
The invention concerns a peptide selected among the group consisting of PF-4, fragments and fusion peptides derived from PF-4, and their analogues, having an angiogenesis-inhibiting activity, wherein the glutamine in position 56 in the native PF-4 is replaced by an arginine, a lysine or a histidine, preferably an arginine. The inventive peptide has an I50 less than the I50 of the same peptide not having a mutation in 56. The invention also concerns DNA or cDNA sequences coding for said peptides and the use of said sequences and/or said peptides for preparing a medicine inhibiting angiogenesis and/or proliferation of cells.
摘要:
The invention relates to an ultra-short laser source with rare earth ions, comprising a resonant cavity (1) having a first partially-reflective output face (2) and a second reflective face (3). The inventive source also comprises a first active material (4) which receives a pump light flux (6) that is emitted by a first solid laser pump source (7). According to the invention, the optical path length of the resonant cavity (1), which is travelled by the aforementioned pulses, is greater than 7.5 m, such that the energy EL per pulse is greater than 100 nJ, said optical path comprising at least one passage in the active material (4). In addition, the ultra-short laser source comprises means for lengthening the resonant cavity (1), which can be used to extend the optical path length travelled by the light pulses in the resonant cavity (1) of a compact laser source. Moreover, the propagation matrix ABCD of the resonant cavity (1) is similar to the unit matrix, such that the characteristics of the light beam travelling to and fro in the resonant cavity (1) are unchanged.
摘要:
L'objet de l'invention est un dispositif caractérisé en ce qu'il est constitué d'un générateur micro-ondes (2) et d'un applicateur micro-ondes (3) sous incidence de Brewster, comprenant un guide d'ondes à l'extrémité duquel est disposé un cache métallique de protection anti-fuites constitué de deux plaques (12,13) parallèles, reliées le long de l'un de leurs côtés par une plaque de liaison (14), l'écartement entre les deux plaques parallèles correspondant à l'épaisseur de la poutre de charpente à traiter et l'une (12) des deux plaques parallèles étant percée d'une ouverture (11) coïncidant avec l'orifice de sortie du guide d'ondes (3) et disposée sensiblement dans la partie centrale de la plaque (12) et avec son axe longitudinal perpendiculaire à ladite plaque de liaison (14), ladite plaque (12) formant avec l'axe (A) du guide d'ondes (3) un angle de l'ordre de 30°. Applications diverses, notamment désinsectisation de pièces de bois.
摘要:
The present invention relates to six-membered cyclic biscarbonates of formula:
wherein: - A is selected from the group consisting of -CH=CH- and -CH 2 CHR'-S-R-S-CHR"CH 2 -, wherein R is a linear or branched alkylene radical in C 2 -C 6 , optionally interrupted by one or more oxygen atoms, and wherein R' and R", identical or different, are selected from the group consisting of hydrogen atom and linear alkyl radicals in C 1 -C 10 ; and - A' and A", identical or different, are linear or branched alkylene radicals in C 1 -C 12 , on the proviso that, when A is -CH 2 CH 2 -S-R-S-CH 2 CH 2 -, A' and A" are in C 2 -C 12 , and their use for the preparation of polymers, such as poly(hydroxyurethane)s.
摘要:
The invention relates to spherical particles formed by polymer chains containing approximately from 30 to 10000 monomer units derived from monocyclic polycyclic alkene polymerisation, wherein at least one monomer unit is substituted by an R chain comprising ethylene polyoxide which is optionally covalently linked to said polymer units through a hydrolysable bridge and substituted by a reactive function, optionally engaged in a link with an active principle or a biological molecule such as protein, wherein said chain R is covalently linked to said monomer units. The use of the inventive spherical particles for preparing pharmaceutical and cosmetic compositions or surface coatings is also disclosed.