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公开(公告)号：EP4081538A1
公开(公告)日：2022-11-02
申请号：EP21701052.9
申请日：2021-01-11
申请人： Universitat Autònoma de Barcelona , Nanoligent, S.L. , Consorcio Centro de Investigación Biomédica en Red , Fundacio Institut de Recerca de l'Hospital de la Santa Creu i sant Pau
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公开(公告)号：EP3911367A1
公开(公告)日：2021-11-24
申请号：EP20726707.1
申请日：2020-01-16
申请人： Universitat Autónoma De Barcelona (UAB) , Fundacio Institut de Recerca de l'Hospital de la Santa Creu i sant Pau , Consorcio Centro de Investigación Biomédica en Red M.P.
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3.发明授权METHODS AND REAGENTS FOR EFFICIENT AND TARGETED DELIVERY OF THERAPEUTIC MOLECULES TO CXCR4 CELLS 有权有效和有针对性地将治疗性分子递送至CXCR4细胞的方法和试剂
公开(公告)号：EP2663336B1
公开(公告)日：2017-08-09
申请号：EP12704711.6
申请日：2012-01-13
申请人： Universitat Autònoma de Barcelona , Fundacio Institut de Recerca de l'Hospital de la Santa Creu i sant Pau , Centro de Investigación Biomédica en Red
发明人： VILLAVERDE CORRALES, Antonio , VÁZQUEZ GÓMEZ, Esther , CÉSPEDES NAVARRO, María Virtudes , CASANOVA RIGAT, Isolda , FERRER MIRALLES, Neus , MANGUES BAFALLUY, Ramon , UNZUETA ELORZA, Ugutz
IPC分类号： A61K47/50 , C07K14/435 , C12N15/62
摘要： The invention relates to conjugates comprising a targeting moiety specific for the CXCR4 based on the polyphemusin-derived peptide and a therapeutic or imaging agent. The invention relates as well to the application of said conjugates for the therapy and diagnostics which require the specific targeting to CXCR4+ cells.
摘要翻译： 本发明涉及包含基于聚肌球蛋白衍生肽的CXCR4特异性靶向部分和治疗剂或成像剂的缀合物。 本发明还涉及所述缀合物用于需要对CXCR4 +细胞进行特异性靶向的治疗和诊断的应用。
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公开(公告)号：EP3953368A1
公开(公告)日：2022-02-16
申请号：EP20736248.4
申请日：2020-04-08
申请人： Universitat Autònoma de Barcelona , Institut Recerca Hospital de la Santa Creu I Sant Pau , Consorcio Centro de Investigación Biomédica en Red, M.P. (CIBER)
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5.发明公开METHODS AND REAGENTS FOR EFFICIENT AND TARGETED DELIVERY OF THERAPEUTIC MOLECULES TO CXCR4 CELLS 有权方法和试剂细胞CXCR4治疗性分子在高效，靶向给药
公开(公告)号：EP2663336A1
公开(公告)日：2013-11-20
申请号：EP12704711.6
申请日：2012-01-13
申请人： Universitat Autònoma De Barcelona , Institut Recerca Hospital de la Santa Creu i Sant Pau , Centro Investigación Biomédica en Red (Ciber BBN)
发明人： VILLAVERDE CORRALES, Antonio , VÁZQUEZ GÓMEZ, Esther , CÉSPEDES NAVARRO, María Virtudes , CASANOVA RIGAT, Isolda , FERRER MIRALLES, Neus , MANGUES BAFALLUY, Ramon , UNZUETA ELORZA, Ugutz
IPC分类号： A61K47/48 , C07K14/435 , C12N15/62
摘要： The invention relates to conjugates comprising a targeting moiety specific for the CXCR4 based on the polyphemusin-derived peptide and a therapeutic or imaging agent. The invention relates as well to the application of said conjugates for the therapy and diagnostics which require the specific targeting to CXCR4+ cells.
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公开(公告)号：EP3619226A2
公开(公告)日：2020-03-11
申请号：EP18726744.8
申请日：2018-05-07
申请人： Universitat Autònoma de Barcelona , Fundació Institut de recerca de l'Hospital de la Santa Creu i Sant Pau , Centro en Investigación Biomédica en Red
发明人： VILLAVERDE CORRALES, Antonio , VÁZQUEZ GÓMEZ, Esther , SERNA ROMERO, Naroa , SÁNCHEZ GARCÍA, Laura , UNZUETA ELORZA, Ugutz , MANGUES BAFALLUY, Ramón , CÉSPEDES NAVARRO, María Virtudes , CASANOVA RIGAT, Isolda
IPC分类号： C07K14/435 , A61K38/10 , C12N15/62
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