专利检索 ap:("University of Washington") AND inv:"HAUSCHKA, Stephen D." 第 1 页

1.

发明公开
ARTIFICIAL REGULATORY CASSETTES FOR MUSCLE-SPECIFIC GENE EXPRESSION 审中-公开

公开(公告)号：EP4319874A2

公开(公告)日：2024-02-14

申请号：EP22785484.1

申请日：2022-04-07

申请人： University of Washington

发明人： CHAMBERLAIN, Jeffrey S. , HAUSCHKA, Stephen D.

IPC分类号： A61P21/00 , C12N15/66 , C12N15/67 , C12N15/85 , C12N15/861

2.

发明公开
NOVEL MICRO-DYSTROPHINS AND RELATED METHODS OF USE 审中-公开
标题翻译：新型微型营养因子及相关使用方法

公开(公告)号：EP3245291A2

公开(公告)日：2017-11-22

申请号：EP16738022.9

申请日：2016-01-15

申请人： University of Washington

发明人： CHAMBERLAIN, Jeffrey S. , RAMOS, Julian , HAUSCHKA, Stephen D.

IPC分类号： C12N15/12 , C07K14/47 , A61K48/00

CPC分类号： C07K14/4708 , A61K38/00 , A61K48/0058 , A61P21/00 , C07H21/04 , C07K14/4707 , C07K14/4716 , C07K2319/30 , C12N15/85 , C12N2750/14143 , C12N2830/008

摘要： Nucleotide sequences including a micro-dystrophin gene are provided. The micro-dystrophin genes may be operatively linked to a regulatory cassette. Methods of treating a subject having, or at risk of developing, muscular dystrophy, sarcopenia, heart disease, or cachexia are also provided. The methods may include administering a pharmaceutical composition including the micro-dystrophin gene and a delivery vehicle to a subject. Further, the methods may include administering the pharmaceutical composition a subject having Duchenne muscular dystrophy or Becker muscular dystrophy.