专利检索 ap:("Ustav organicke chemie a biochemie AV CR, v.v.i." OR "Biotechnologicky Ustav AV CR, v.v.i.") AND inv:"KODEDOVA, Marie" 第 1 页

1.

发明公开
ANTIMICROBIAL PEPTIDES AND THEIR USE FOR THE TREATMENT OF TOPICAL INFECTIONS 有权
标题翻译：抗微生物肽及其用于治疗局部感染的用途

公开(公告)号：EP3280722A1

公开(公告)日：2018-02-14

申请号：EP16721001.2

申请日：2016-04-08

申请人： Ustav organicke chemie a biochemie AV CR, v.v.i. , Biotechnologicky Ustav AV CR, v.v.i.

发明人： CEROVSKY, Vaclav , NESUTA, Ondrej , DUDKOVA, Vlasta , SYCHROVA, Hana , KODEDOVA, Marie

IPC分类号： C07K7/08 , A61K38/04

CPC分类号： C07K7/08 , A61K38/00 , A61K38/04 , A61K38/10

摘要： Synthetic analogs of general formula (I-A), 5 a-Ile-b-c-d-e-f-Lys-Lys-g-h-i-j-Ile-k-Lys-NH2 (I-A) where a is Gly, Lys or β-Ala; b is Met, Leu, Nle, Ile, Trp, Val or Phe; c is Ser, Lys, Arg or Orn; d is Ser, Lys, Arg or Orn; e is Leu, Nle, Ile, Trp, Val or Phe; f is Met, Leu, Nle, Ile, Trp, Val or Phe; g is Leu, Nle, Ile orTrp; h is Lys, Arg, Orn or Ala; i is Lys, Arg, Orn or Ala; j is Ile, Leu, Nle or His; k is Lys, Arg, Orn or Ala; where amino acids in all positions may be in D-configuration, and their use for the treatment of topical infections caused by pathogenic bacteria or yeasts.

2.

发明授权
ANTIMICROBIAL PEPTIDES AND THEIR USE FOR THE TREATMENT OF TOPICAL INFECTIONS 有权

公开(公告)号：EP3280722B1

公开(公告)日：2019-05-15

申请号：EP16721001.2

申请日：2016-04-08

申请人： Ustav organicke chemie a biochemie AV CR, v.v.i. , Biotechnologicky Ustav AV CR, v.v.i.

发明人： CEROVSKY, Vaclav , NESUTA, Ondrej , DUDKOVA, Vlasta , SYCHROVA, Hana , KODEDOVA, Marie

IPC分类号： C07K7/08 , A61K38/04

CPC分类号： C07K7/08 , A61K38/00 , A61K38/04 , A61K38/10

摘要： Synthetic analogs of general formula (I-A), 5 a-Ile-b-c-d-e-f-Lys-Lys-g-h-i-j-Ile-k-Lys-NH2 (I-A) where a is Gly, Lys or β-Ala; b is Met, Leu, Nle, Ile, Trp, Val or Phe; c is Ser, Lys, Arg or Orn; d is Ser, Lys, Arg or Orn; e is Leu, Nle, Ile, Trp, Val or Phe; f is Met, Leu, Nle, Ile, Trp, Val or Phe; g is Leu, Nle, Ile orTrp; h is Lys, Arg, Orn or Ala; i is Lys, Arg, Orn or Ala; j is Ile, Leu, Nle or His; k is Lys, Arg, Orn or Ala; where amino acids in all positions may be in D-configuration, and their use for the treatment of topical infections caused by pathogenic bacteria or yeasts.

3.

发明授权
ANTIMICROBIAL PEPTIDES AND THEIR USE FOR THE TREATMENT OF TOPICAL INFECTIONS 有权

公开(公告)号：EP3280722B8

公开(公告)日：2019-06-26

申请号：EP16721001.2

申请日：2016-04-08

申请人： Ustav organicke chemie a biochemie AV CR, v.v.i. , Fyziologicky ustav AV CR, v.v.i.

发明人： CEROVSKY, Vaclav , NESUTA, Ondrej , DUDKOVA, Vlasta , SYCHROVA, Hana , KODEDOVA, Marie

IPC分类号： C07K7/08 , A61K38/04