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    METHODS OF TREATING METABOLIC SYNDROME USING DOPAMINE RECEPTOR AGONISTS
    3.
    发明公开
    METHODS OF TREATING METABOLIC SYNDROME USING DOPAMINE RECEPTOR AGONISTS 审中-公开
    方法代谢综合征与多巴胺受体激动剂治疗

    公开(公告)号：EP2175853A4

    公开(公告)日：2010-11-17

    申请号：EP08742225

    申请日：2008-03-24

    申请人： VEROSCIENCE LLC

    发明人： CINCOTTA ANTHONY H

    IPC分类号： A61K31/44 ,  A61P3/10 ,  A61P9/10

    CPC分类号： A61K45/06 ,  A61K31/48

    摘要： The present invention is directed to a method of simultaneously treating hypertension, hypertriglyceridemia, a pro-inflammatory state, a pro-coagulative state, and insulin resistance (with or without treating obesity or endothelial dysfunction), associated with or independent from Metabolic Syndrome, as well as vascular disease such as cardiovascular, cerebrovascular, or peripheral vascular disease comprising the step of administering to a patient suffering from such disorders a therapeutically effective amount of a central acting dopamine agonist. In one embodiment, the central acting dopamine agonist is bromocriptine, optionally combined with a pharmaceutically acceptable carrier.

    摘要翻译： 本发明涉及的同时治疗高血压，高甘油三酯血症，促炎症状态，促凝血状态，和胰岛素抗性（有或没有治疗肥胖症或内皮功能障碍），有或独立于代谢综合征相关的方法，如 以及血管疾病：如心血管，脑血管或外周血管疾病包括从寻求治疗有效量的中央作用的多巴胺激动剂的疾病给予的患者的步骤。 在一个，作用多巴胺激动剂的中央实施方式是溴隐亭，任选与药学上可接受的载体组合。