公开(公告)号：EP2323680A2

公开(公告)日：2011-05-25

申请号：EP09800676.0

申请日：2009-07-23

申请人： Viral Genetics, Inc. ,  The Regents of the University of Colorado

发明人： KELEDJIAN, Haig ,  AGADJANYAN, Michael ,  NEWELL, Martha, Karen ,  NEWELL, Evan

IPC分类号： A61K38/08 ,  A61K35/26 ,  A61K39/39 ,  A61P31/18 ,  A61P25/28 ,  A61P35/00 ,  G01N33/68

CPC分类号： A61K35/26 ,  A61K38/08 ,  A61K38/10 ,  C07K14/47 ,  G01N33/56988 ,  G01N2333/5759 ,  Y02A50/401 ,  Y02A50/57

摘要： The present invention describes compositions of thymus derived peptides and uses therefore in diagnostic methods and for the treatment of diseases associated with reduced T helper cell counts, diseases such as infection, e.g., HIV infection and other viral infections, parasitic, and bacterial infection, AIDS, ARC, multiple sclerosis, chronic fatigue syndrome, rheumatoid arthritis, Alzheimer's disease, asthma, allergy, dermatitis, type 1 diabetes mellitus, colitis, inflammatory bowel disease/irritable bowel syndrome, Crohn's disease, Psoriasis, Chronic obstructive pulmonary disease, Systemic lupus erythematosus, transplant rejection and cancer.

公开(公告)号：EP2323679A2

公开(公告)日：2011-05-25

申请号：EP09800699.2

申请日：2009-07-23

申请人： The Regents of the University of Colorado ,  Viral Genetics, Inc.

发明人： NEWELL, Martha, Karen ,  NEWELL, Evan ,  KELEDJIAN, Haig ,  AGADJANYAN, Michael

IPC分类号： A61K38/08 ,  A61K33/06 ,  A61P31/18 ,  A61P1/16 ,  A61P37/08 ,  A61P33/06

CPC分类号： A61K45/06 ,  A61K38/08 ,  Y02A50/401 ,  Y02A50/409 ,  Y02A50/411 ,  Y02A50/465 ,  Y02A50/471 ,  Y02A50/475 ,  Y02A50/57 ,  A61K2300/00

摘要： The invention relates to methods for modulating the immune function through targeting of CLIP molecules. The result is wide range of new therapeutic regimens for treating, inhibiting the development of, or otherwise dealing with, a multitude of illnesses and conditions, including autoimmune disease, allergic disease transplant and cell graft rejection, cancer, bacterial infection, HIV infection, and AIDS.

公开(公告)号：EP2089420A2

公开(公告)日：2009-08-19

申请号：EP07867230.0

申请日：2007-10-15

申请人： Viral Genetics, Inc.

发明人： AGADJANYAN, Michael ,  KELEDJIAN, Haig

IPC分类号： C07K14/00 ,  A61K39/00 ,  A61K39/12

CPC分类号： A61K38/57 ,  Y02A50/471 ,  A61K2300/00

摘要： The present invention describes a composition comprised on cystatin A and at least one histone used in diagnostic tools and for the treatment of diseases associated with reduced T helper cell counts such as HIV-1 infection, AIDS, ARC, multiple sclerosis, chronic fatigue syndrome, heumatoid arthritis, Alzheimer's disease, dermatitis, type 1 diabetes mellitus, colitis, inflammatory bowel disease / irritable bowel syndrome, Crohn's disease, Psoriasis, Chronic obstructive pulmonary disease, System lupus erythematosus, transplant rejection and cancer.