公开(公告)号：EP1345743B1

公开(公告)日：2008-07-23

申请号：EP01995191.2

申请日：2001-11-16

申请人： Virginia Commonwealth University Intellectual Property Foundation

发明人： SIMPSON, David, G. ,  BOWLIN, Gary, L. ,  WNEK, Gary, E. ,  STEVENS, Peter, J. ,  CARR, Marcus, E., Jr. ,  MATTHEWS, Jamil, A. ,  RAJENDRAN, Saravanamoorthy

IPC分类号： B29C41/00 ,  C07K14/78 ,  A61L15/32

CPC分类号： C12N5/0068 ,  A61K2035/126 ,  A61L15/32 ,  A61L27/24 ,  A61L27/26 ,  A61L27/38 ,  A61L31/041 ,  A61L2400/04 ,  B29C41/006 ,  B29C67/0007 ,  C07K14/78 ,  C12N5/0012 ,  C12N2533/40 ,  C12N2533/54 ,  D01D5/0038 ,  D01F1/10 ,  D01F4/00 ,  C08L89/06

摘要： The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.

公开(公告)号：EP1333808B1

公开(公告)日：2012-07-25

申请号：EP01987661.4

申请日：2001-10-18

申请人： Virginia Commonwealth University Intellectual Property Foundation

发明人： SIMPSON, David, G. ,  BOWLIN, Gary, L. ,  WNEK, Gary, E.

IPC分类号： A61L15/32 ,  A61L27/22 ,  A61L27/24 ,  A61L27/26 ,  A61L27/38 ,  C07K14/78 ,  C12N5/00 ,  A61L31/04 ,  C08L89/00 ,  B29C67/00 ,  B29C41/00 ,  C07K14/75

CPC分类号： C12N5/0068 ,  A61K2035/126 ,  A61L15/32 ,  A61L27/225 ,  A61L27/24 ,  A61L27/26 ,  A61L27/38 ,  A61L27/3847 ,  A61L31/041 ,  A61L2400/04 ,  B29C41/006 ,  B29C67/0007 ,  C07K14/75 ,  C07K14/78 ,  C12N5/0012 ,  C12N2533/40 ,  C12N2533/54 ,  C12N2533/56 ,  D01D5/0007 ,  D01F1/10 ,  C08L89/00

摘要： The invention is directed to novel compositions comprising an electroprocessed material and a substance, their formation and use. The electroprocessed material can, for example, be one or more natural materials, one or more synthetic materials, or a combination thereof. The substance can be one or more therapeutic or cosmetic substances or other compounds, molecules, cells, vesicles. The compositions can be used in substance delivery, including drug delivery within an organism by, for example, releasing substances or containing cells that release substances. The compositions can be used for other purposes, such as prostheses or similar implants.