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公开(公告)号：EP3488893B1
公开(公告)日：2020-07-15
申请号：EP19151719.2
申请日：2012-10-05
发明人： BACINO, John, E. , CAMPBELL, Carey, V. , CULLY, Edward, H. , DUNCAN, Jeffrey, B. , PAGET, Douglas, S. , SHAW, Edward, E. , SQUERI, John, M. , TRAPP, Benjamin, M. , VONESH, Michael, J.
IPC分类号： A61M25/10 , A61B17/3207
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公开(公告)号：EP3178501A1
公开(公告)日：2017-06-14
申请号：EP16198801.9
申请日：2012-03-02
发明人： CAMPBELL, Carey, V. , CLEEK, Robert, L. , HOLLAND, Theresa, A. , KRANZLER, Thane, L. , LI, Mei , TRAPP, Benjamin, M.
CPC分类号： A61M25/104 , A61F2/82 , A61F2250/0023 , A61F2250/0035 , A61F2250/0067 , A61L29/085 , A61L29/146 , A61L29/16 , A61L2300/416 , A61L2300/606 , A61M2025/09125 , A61M2025/1031 , A61M2025/105 , A61M2025/1075 , A61M2025/1081
摘要： The invention is directed to eluting medical devices that enable consistent "on-demand" delivery of therapeutic agents to a vessel. The medical device of the current invention comprises an expandable member, a hydrophilic coating comprising at least one therapeutic agent about the expandable member or structural layer and an outer sheath with a variably permeable microstructure. The design and methods disclosed herein ensures that therapeutic agent delivery occurs essentially only during expansion of the expandable member, minimizing coating and/or therapeutic agent loss to the bloodstream and providing controlled delivery to the treatment site.
摘要翻译： 本发明涉及洗脱能够使治疗剂一致“按需”递送至脉管的医疗装置。 本发明的医疗装置包括可膨胀构件，亲水性涂层，其包含围绕可膨胀构件或结构层的至少一种治疗剂和具有可变渗透性微结构的外护套。 本文公开的设计和方法确保治疗剂递送基本上仅在可扩张构件扩张期间发生，使涂层和/或治疗剂损失到血流最小化并向治疗部位提供受控递送。
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公开(公告)号：EP2768426A2
公开(公告)日：2014-08-27
申请号：EP12780974.7
申请日：2012-10-11
发明人： BRUCHMAN, William, C. , CULLY, Edward, H. , HARTMAN, Cody, L. , LOVEKAMP, Joshua, J. , TRAPP, Benjamin, M.
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2210/0014 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/008 , A61F2250/0023
摘要： According to one aspect of the disclosure, an embolic protection device is provided comprising an elongate element having a deflector at its distal end. The embolic protection device is generally configured to redirect and/or funnel embolic debris and permit at least a portion of the blood, no longer containing the redirected and/or funneled embolic debris, to perfuse the surrounding vasculature and/or tissue.
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公开(公告)号：EP4218883A1
公开(公告)日：2023-08-02
申请号：EP23165255.3
申请日：2011-12-16
IPC分类号： A61M25/00
摘要： Apparatus and methods for an endovascular catheter that can be inserted within tortuous body anatomies and then selectively stiffened and fixed in place. In a particular embodiment, this stiffness is reversible. The stiffness or a comparable mechanical characteristic of the catheter assembly may be adjusted to a relatively low value during insertion (so that it easily navigates a guide wire or the like), and then subsequently adjusted to a relatively high value in situ to keep the catheter assembly substantially fixed in place (i.e., during delivery of an interventional device).
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公开(公告)号：EP2063791B1
公开(公告)日：2016-12-21
申请号：EP07811013.7
申请日：2007-08-01
CPC分类号： A61B17/320725 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B17/12172 , A61B17/221 , A61B2017/12127 , A61B2017/320716 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0065 , A61F2230/0069 , A61F2230/0071 , A61F2230/0078
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公开(公告)号：EP2696931B1
公开(公告)日：2015-06-03
申请号：EP12718506.4
申请日：2012-04-14
IPC分类号： A61M25/10
CPC分类号： A61F2/958 , A61F2/82 , A61F2210/0061 , A61F2250/0067 , A61F2250/0069 , A61M25/10 , A61M25/1018 , A61M2025/1068 , A61M2025/1084
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公开(公告)号：EP3789073A1
公开(公告)日：2021-03-10
申请号：EP20185756.2
申请日：2012-10-05
发明人： BACINO, John, E. , CAMPBELL, Carey, V. , CULLY, Edward, H. , DUNCAN, Jeffrey, B. , PAGET, Douglas, S. , SHAW, Edward, E. , SQUERI, John, M. , TRAPP, Benjamin, M. , VONESH, Michael, J.
IPC分类号： A61M25/10 , A61B17/3207
摘要： Various embodiments provide a device comprising a balloon disposed at least partially along a template, the template including an aperture, wherein the template has a substantially cylindrical portion that resists deformation in a radial direction, wherein the balloon expands radially during inflation, wherein a portion of the balloon at least partially protrudes about the aperture. Other embodiments are directed toward balloons having textured surfaces.
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公开(公告)号：EP3488893A1
公开(公告)日：2019-05-29
申请号：EP19151719.2
申请日：2012-10-05
发明人： BACINO, John, E. , CAMPBELL, Carey, V. , CULLY, Edward, H. , DUNCAN, Jeffrey, B. , PAGET, Douglas, S. , SHAW, Edward, E. , SQUERI, John, M. , TRAPP, Benjamin, M. , VONESH, Michael, J.
IPC分类号： A61M25/10 , A61B17/3207
摘要： Various embodiments provide a device comprising a balloon (200) disposed at least partially along a template (220), the template including at least one aperture (221), wherein the template has a substantially cylindrical portion that resists deformation in a radial direction, wherein the balloon expands radially during inflation, wherein a portion of the balloon at least partially protrudes about the at least one aperture.
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公开(公告)号：EP2613842B1
公开(公告)日：2017-07-05
申请号：EP11758062.1
申请日：2011-09-09
发明人： CULLY, Edward, H. , DUNCAN, Jeffrey, B. , MAULDING, Matthew, E. , TRAPP, Benjamin, M. , SCHONHOLZ, Claudio
CPC分类号： A61M25/005 , A61M25/0013 , A61M25/0026 , A61M25/0045 , A61M25/0068 , A61M25/0082 , A61M25/04 , A61M2025/0004 , A61M2025/0019 , A61M2025/0024 , A61M2025/0031 , A61M2025/0034 , A61M2025/0036 , A61M2025/004 , A61M2025/0057 , A61M2025/006 , A61M2025/0073 , A61M2025/0076 , A61M2025/0175 , A61M2025/1047 , A61M2202/0283 , A61M2202/04
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公开(公告)号：EP2780050A1
公开(公告)日：2014-09-24
申请号：EP12769525.2
申请日：2012-09-05
发明人： CAMPBELL, Carey, V. , CLEEK, Robert, L. , CRANDALL, Daniel, L. , DAVIDSON, James, F. , DRUMHELLER, Paul, D. , HARTMAN, Cody, L. , HOLLAND, Theresa, A. , KRANZLER, Thane, L. , LI, Mei , LOSTRACCO, Gregory , STEINHAUS, Bruce, M. , TRAPP, Benjamin, M. , TRIEBES, Thomas, G.
CPC分类号： A61M25/10 , A61L29/085 , A61L29/16 , A61L2300/602 , A61M2025/105 , A61M2025/1081 , F04C2270/0421
摘要： The invention is directed to eluting medical devices that enable consistent "on-demand" delivery of therapeutic agents to a vessel. The medical device of the current invention comprises an expandable member, a hydrophilic coating comprising at least one therapeutic agent about the expandable member or structural layer and an outer sheath with a variably permeable microstructure. The design and methods disclosed herein ensures that therapeutic agent delivery occurs essentially only during expansion of the expandable member, minimizing coating and/or therapeutic agent loss to the bloodstream and providing controlled delivery to the treatment site.
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