公开(公告)号：EP0749321A4

公开(公告)日：2001-04-25

申请号：EP95911683

申请日：1995-02-09

申请人： WILLMAR POULTRY CO INC ,  EMERY DARYLL A ,  STRAUB DARREN E ,  HUISINGA RICHARD ,  CARLSON BETH A

发明人： EMERY DARYLL A ,  STRAUB DARREN E ,  HUISINGA RICHARD ,  CARLSON BETH A

IPC分类号： A61K39/102 ,  A61P31/04 ,  G01N33/569 ,  A61K39/00 ,  A61K39/104 ,  A61K39/108 ,  A61K39/112 ,  A61K39/38 ,  A61K39/395 ,  A61K39/40 ,  C07K16/12

CPC分类号： C07K14/245 ,  A61K39/0258 ,  A61K39/0275 ,  A61K39/102 ,  G01N33/56911 ,  G01N33/56916 ,  Y10S424/823 ,  Y10S424/824 ,  Y10S424/825 ,  Y10S424/826 ,  Y10S530/825

摘要： The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a single strain or species of gram-negative bacteria or other organism, which are cross-reactive with siderophores produced by two or more strains, species or genera of gram-negative bacteria. The invention further provides a process for isolating and purifying the siderophore receptor proteins, and for preparing a vaccine containing the proteins. Also provided is a method for diagnosing gram-negative sepsis.

公开(公告)号：EP0804164A4

公开(公告)日：1998-08-05

申请号：EP95938205

申请日：1995-02-02

申请人： WILLMAR POULTRY CO INC

发明人： EMERY DARYLL A ,  STRAUB DARREN E ,  HUISINGA RICHARD

IPC分类号： A61K9/00 ,  A61K39/00 ,  A61P37/04 ,  A61K9/14 ,  A61K9/127

CPC分类号： A61K9/0024