专利检索 ap:("Walter Reed Army Institute of Research") AND inv:"LANAR, David, E." 第 1 页

1.

发明授权
EXPRESSION, PURIFICATION AND USES OF A PLASMODIUM FALCIPARUM LIVER STAGE ANTIGEN 1 POLYPEPTIDE 有权
标题翻译：表达，清洁和肝恶性疟原虫相抗原-1多肽的使用

公开(公告)号：EP1569674B1

公开(公告)日：2014-12-24

申请号：EP03768878.5

申请日：2003-11-12

申请人： Walter Reed Army Institute of Research

发明人： LANAR, David, E. , HILLIER, Collette, J. , LYON, Jeffrey, A. , ANGOV, Evelina , KUMAR, Sanjai , ROGERS, William c/o Dept. of State , BARBOSA, Arnoldo

IPC分类号： C12N15/67 , C12N15/10 , C12N15/30 , C12N1/21 , G06F17/30 , G06F19/00 , A61K39/015 , A61P33/06

CPC分类号： A61K39/015 , A61K2039/55505 , A61K2039/55566 , C07K14/445 , C07K16/205 , C12N15/67 , C12P21/02 , G01N33/56905 , G01N2333/445 , Y02A50/412 , Y02A90/26

摘要： In this application is described the expression and purification of a recombinant Plasmodium falciparum (3D7) LSA-NRC polypeptide. The method of the present invention produces a highly purified polypeptide which is useful as a vaccine and as a diagnostic reagent.

2.

发明公开
RECOMBINANT P. VIVAX MEROZOITE PROTEIN-1 P42 VACCINE 审中-公开
标题翻译：重组间日疟原虫裂殖子蛋白-1 P-42疫苗

公开(公告)号：EP1370581A2

公开(公告)日：2003-12-17

申请号：EP02753657.2

申请日：2002-03-18

申请人： Walter Reed Army Institute of Research

发明人： LANAR, David, E. , DUTTA, Sheetij , WARE, Lisa, A.

IPC分类号： C07K14/445 , C12N15/12 , C12N15/85 , C12N5/10 , C07K16/20 , G01N33/569 , A61K39/015

CPC分类号： C07K14/445 , A61K39/00 , Y02A50/412

摘要： In this application is the expression and purification of a recombinant Plasmodium vivax (SalI) PvMSP-1 p42. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant PvMSP-1 p42 is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.

3.

发明公开
EXPRESSION, PURIFICATION AND USES OF A PLASMODIUM FALCIPARUM LIVER STAGE ANTIGEN 1 POLYPEPTIDE 有权
标题翻译：表达，清洁和肝恶性疟原虫相抗原-1多肽的使用

公开(公告)号：EP1569674A2

公开(公告)日：2005-09-07

申请号：EP03768878.5

申请日：2003-11-12

申请人： Walter Reed Army Institute of Research

发明人： LANAR, David, E. , HILLIER, Collette, J. , LYON, Jeffrey, A. , ANGOV, Evelina , KUMAR, Sanjai , ROGERS, William c/o Dept. of State , BARBOSA, Arnoldo

IPC分类号： A61K38/00 , A61K39/395 , C12N15/63

CPC分类号： A61K39/015 , A61K2039/55505 , A61K2039/55566 , C07K14/445 , C07K16/205 , C12N15/67 , C12P21/02 , G01N33/56905 , G01N2333/445 , Y02A50/412 , Y02A90/26

摘要： In this application is described the expression and purification of a recombinant Plasmodium falciparum (3D7) LSA-NRC polypeptide. The method of the present invention produces a highly purified polypeptide which is useful as a vaccine and as a diagnostic reagent.

4.

发明公开
PLASMODIUM FALCIPARUM AMA-1 PROTEIN AND USES THEREOF 审中-公开
标题翻译：蛋白AMA-1 OFF恶性疟原虫及其用途

公开(公告)号：EP1423405A2

公开(公告)日：2004-06-02

申请号：EP02753857.8

申请日：2002-03-25

申请人： Walter Reed Army Institute of Research

发明人： LANAR, David, E. , DUTTA, Sheetij , WARE, Lisa, A. , NAIR, Lalitha, P., V.

IPC分类号： C07H21/04 , C07H21/02 , C12P21/06 , C12P21/04 , C12N15/00

CPC分类号： C07K14/445 , A61K39/00 , Y02A50/412

摘要： In this application is described the expression and purification of a recombinant Plasmodium falciparum (3D7) AMA-1 ectodomain. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant AMA-1 is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.