专利检索 ap:("Wyeth") AND inv:"KIM, Ji-ln" 第 1 页

1.

发明公开
AMINO-5-[SUBSTITUTED-4-(DIFLUOROMETHOXY)PHENYL]-5- PHENYLIMIDAZOLONE COMPOUNDS AS ß-SECRETASE INHIBITORS 审中-公开
标题翻译：氨基-5- [取代的] -4-（二氟甲氧基）苯基] -5- PHENYLIMIDAZOLON化合物作为β-分泌缝边

公开(公告)号：EP2137161A1

公开(公告)日：2009-12-30

申请号：EP08727031.0

申请日：2008-03-20

申请人： Wyeth

发明人： MALAMAS, Michael Sotirios , ROBICHAUD, Albert Jean , PORTE, Alexander Michael , SOLVIBILE, William Ronald , MORRIS, Koi Michele , ANTANE, Schuyler Adam , KIM, Ji-ln , MCDEVITT, Robert Emmett

IPC分类号： C07D233/88

CPC分类号： C07D233/88

摘要： The present invention provides a 2-amino-5-[substituted-4-(difluoromethoxy)phenyl]-5-phenylimidazolone compound of formula (I) The present invention also provides methods for the use thereof to inhibit ß-secretase (BACE) and treat ß-amyloid deposits and neurofibrillary tangles.