公开(公告)号：EP3305811B1

公开(公告)日：2020-04-01

申请号：EP16802575.7

申请日：2016-06-02

申请人： Xiamen University

发明人： CHEN, Yixin ,  SHEN, Chenguang ,  CHEN, Junyu ,  WANG, Guosong ,  ZHANG, Mengya ,  XIA, Ningshao

IPC分类号： C07K16/10 ,  C12N15/13 ,  C12N15/63 ,  C12N5/20 ,  G01N33/577 ,  G01N33/569 ,  A61K39/42 ,  A61P31/16 ,  C12N7/00

公开(公告)号：EP3305811A1

公开(公告)日：2018-04-11

申请号：EP16802575.7

申请日：2016-06-02

申请人： Xiamen University

发明人： CHEN, Yixin ,  SHEN, Chenguang ,  CHEN, Junyu ,  WANG, Guosong ,  ZHANG, Mengya ,  XIA, Ningshao

IPC分类号： C07K16/10 ,  C12N15/13 ,  C12N15/63 ,  C12N5/20 ,  G01N33/577 ,  G01N33/569 ,  A61K39/42 ,  A61P31/16

摘要： Provided are a broad-spectrum monoclonal anti-Flu B antibody, cell strains generating the antibody, and a composition comprising the antibody; also provided are uses of the antibody for diagnosing, preventing and/or treating an infection of the Flu B and/or diseases caused by the infection.

摘要翻译： 提供广谱单克隆抗Flu B抗体，产生该抗体的细胞株和包含该抗体的组合物; 还提供了抗体用于诊断，预防和/或治疗流感B感染和/或感染引起的疾病的用途。

公开(公告)号：EP3699186A1

公开(公告)日：2020-08-26

申请号：EP18869363.4

申请日：2018-10-10

申请人： Xiamen University

发明人： CHEN, Yixin ,  SHEN, Chenguang ,  CHEN, Junyu ,  ZHANG, Mengya ,  ZHANG, Limin ,  XIA, Ningshao

IPC分类号： C07K14/11 ,  C12N15/44 ,  C12N15/09 ,  C12N7/00 ,  A61K39/145 ,  A61P31/16

摘要： The disclosure relates to a mutant of hemagglutinin protein of H3N2 subtype influenza virus and use thereof. In addition, the disclosure also relates to a pharmaceutical composition (e.g., a vaccine) comprising the mutant, a method for preparing the mutant, and a method of using the mutant for prevention and/or treatment of an infection of influenza virus and/or a disease (e.g., an influenza) caused by the infection.