-
1.发明公开High penetration prodrug compositions of peptides and peptide-related compounds 审中-公开前体药物 - 佐佐门en en her her her her en en en en en en en en en en en en en
公开(公告)号：EP2660247A3
公开(公告)日：2014-09-03
申请号：EP13170316.7
申请日：2010-05-10
发明人： Yu, Chongxi , Xu, Lina , Chen, Yuhua , Yan, Binbing , Tu, Shiqian
IPC分类号： C07K7/06 , C07K7/08 , C07K14/00 , C07K1/04 , A61K38/08 , A61K38/10 , A61K38/16 , A61P17/00 , A61P25/00 , A61K47/48
CPC分类号： A61K31/145 , A61K9/0014 , A61K31/222 , A61K31/40 , A61K31/4184 , A61K38/00 , A61K47/42 , A61K47/54 , A61K47/64 , A61K47/645 , C07D403/12 , C07D403/14 , C07K1/04 , C07K5/06026 , C07K5/06078 , C07K5/1013 , C07K5/1016 , C07K5/1019 , C07K7/06 , C07K7/56
摘要： Provided is a high penetration composition or high penetration prodrugs of peptide or peptide-related compound comprising functional unit, linker, and transportational unit. The functional unit is covalently linked to the transportational unit via the linker, and comprises a moiety of the peptide or the peptide-related compound. The transportational unit comprises protonatable amine group. The linker comprises chemical bond that is capable of being cleaved after the composition penetrates across a biological barrier.
摘要翻译： 提供了包含功能单元，接头和运输单元的肽或肽相关化合物的高渗透组合物或高渗透前药。 功能单元通过接头与运输单元共价连接，并且包含肽或肽相关化合物的部分。 运输单元包括可质子胺基团。 连接体包括能够在组合物渗透生物屏障之后被切割的化学键。
-
2.发明公开High penetration prodrug compositions of peptides and peptide-related compounds 审中-公开具有肽和肽的化合物的高渗透的前药的组合物
公开(公告)号：EP2660247A2
公开(公告)日：2013-11-06
申请号：EP13170316.7
申请日：2010-05-10
发明人： Yu, Chongxi , Xu, Lina , Chen, Yuhua , Yan, Binbing , Tu, Shiqian
IPC分类号： C07K7/06 , C07K7/08 , C07K14/00 , C07K1/04 , A61K38/08 , A61K38/10 , A61K38/16 , A61P17/00 , A61P25/00 , A61K47/48
CPC分类号： A61K31/145 , A61K9/0014 , A61K31/222 , A61K31/40 , A61K31/4184 , A61K38/00 , A61K47/42 , A61K47/54 , A61K47/64 , A61K47/645 , C07D403/12 , C07D403/14 , C07K1/04 , C07K5/06026 , C07K5/06078 , C07K5/1013 , C07K5/1016 , C07K5/1019 , C07K7/06 , C07K7/56
摘要： Provided is a high penetration composition or high penetration prodrugs of peptide or peptide-related compound comprising functional unit, linker, and transportational unit. The functional unit is covalently linked to the transportational unit via the linker, and comprises a moiety of the peptide or the peptide-related compound. The transportational unit comprises protonatable amine group. The linker comprises chemical bond that is capable of being cleaved after the composition penetrates across a biological barrier.
-
搜索结果
2 条记录 (耗时 0.01 秒)
