公开(公告)号：EP2688876A1

公开(公告)日：2014-01-29

申请号：EP12710793.6

申请日：2012-03-08

申请人： ZOETIS LLC

发明人： VAILLANCOURT, Valerie A. ,  WENDT, John A. ,  KYNE, Graham ,  MENON, Sanjay

IPC分类号： C07D261/04 ,  C07D413/10 ,  A01N43/80 ,  A01P7/02 ,  A01P7/04

CPC分类号： A61K31/422 ,  A01N43/80 ,  A01N55/00 ,  A61K31/42 ,  A61K45/06 ,  C07D261/04 ,  C07D413/10

摘要： This invention recites isoxazoline substituted derivatives of Formula (1) stereoisomers thereof, geometric isomers thereof, veterinarily acceptable salts 5 thereof, compositions thereof, and their use as a parasiticide in animals. The variables A, W, R 1a, R 1b, R 1c, R 2, R 3, R 5, and n are as described herein.

公开(公告)号：EP2892902A1

公开(公告)日：2015-07-15

申请号：EP13762671.9

申请日：2013-09-04

申请人： Zoetis LLC

发明人： SHEEHAN, Susan M. K. ,  VAILLANCOURT, Valerie A.

IPC分类号： C07D491/10 ,  A61K31/397 ,  A61P33/00

CPC分类号： C07D491/107

摘要： The invention recites spirocyclic derivatives of Formula (V.1) or (V.2), stereoisomers thereof, veterinary acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide for an animal. The variables A, B, V, Z, Y, W
1 , W
2, W
3 , R
1a , R
1b , R
1c , R
2 , R
3 , R
4 , n, and "---" are as described herein.

公开(公告)号：EP2892901A1

公开(公告)日：2015-07-15

申请号：EP13762669.3

申请日：2013-09-04

申请人： Zoetis LLC

发明人： MENON, Sanjay ,  SHEEHAN, Susan M.K. ,  VAILLANCOURT, Valerie A.

IPC分类号： C07D491/10 ,  A61K31/397 ,  A61P33/00 ,  C07D491/20 ,  C07D495/10

CPC分类号： A01N43/90 ,  C07D491/20 ,  C07D495/10

摘要： The invention recites spirocyclic isoxazoline derivatives of Formula (1) stereoisomers thereof, veterinary or pharmaceutical acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide in an animal. The variables W
1 , W
2 , W
3 , W, X, R
1a , R
1b , R
1c , R
2 , R
3 , R
4 , and n are as described herein.

公开(公告)号：EP2683723A1

公开(公告)日：2014-01-15

申请号：EP12709376.3

申请日：2012-02-23

申请人： Zoetis LLC

发明人： BILLEN, Denis ,  CHUBB, Nathan Anthony Logan ,  CURTIS, Michael ,  GREENWOOD, Sean DW ,  MENON, Sanjay ,  STUK, Timothy ,  VAILLANCOURT, Valerie A.

IPC分类号： C07D491/10 ,  A01N43/80

CPC分类号： C07D491/10 ,  A01N43/90

摘要： The invention recites spirocyclic isoxazoline derivatives of Formula (V.1), Formula (V.2), Formula (V.1.1), and Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide in an animal. The variables A, V, Z, W
1 , W
2 , W
3 , W, Y, X, R
1a , R
1b , R
1c , R
2 , R
3 , R
4 , n, and --- are as described herein.