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    Mammalian cytokine-like polypeptide-10
    1.
    发明公开
    Mammalian cytokine-like polypeptide-10 审中-公开
    哺乳动物细胞因子样多肽-10

    公开(公告)号：EP1424393A2

    公开(公告)日：2004-06-02

    申请号：EP04002769.0

    申请日：1998-11-25

    申请人： Zymogenetics Inc

    发明人： Conklin, Darrell C. ,  Haldeman, Betty A. ,  Grossmann, Angelika

    IPC分类号： C12N15/12 ,  C07K14/52 ,  C07K16/24 ,  A61K38/19 ,  G01N33/53

    CPC分类号： C07K14/54 ,  A01K67/027 ,  A01K2217/05 ,  A61K38/00 ,  A61K48/00 ,  C07K14/52 ,  C12N2799/021

    摘要： Use of a mammalian cytokine-like polypeptide, called Zcyto10, and polynucleotides encoding the same, for the manufacture of a medicament for the prevention or treatment of an autoimmune disease or condition. In a preferred embodiment, said use is for treating a disease or condition selected from the group consisting of immune dependent diabetes mellitus (IDDM), multiple sclerosis, rheumatoid arthritis, cancer cell growth or proliferation, asthma, bronchitis, thrombocytopenia in cancer patients due to chemotherapy or radiation therapy, psoriasis, eczema, and dry skin conditions.

    摘要翻译： 称为Zcyto10的哺乳动物细胞因子样多肽和编码它的多核苷酸用于制备用于预防或治疗自身免疫疾病或病症的药物的用途。 在一个优选的实施方案中，所述用途是用于治疗癌症患者中选自由免疫依赖性糖尿病（IDDM），多发性硬化症，类风湿性关节炎，癌细胞生长或增殖，哮喘，支气管炎，血小板减少症组成的组的疾病或病症， 化疗或放疗，牛皮癣，湿疹和皮肤干燥症。

    Mammalian cytokine-like polypeptide-10
    2.
    发明公开
    Mammalian cytokine-like polypeptide-10 审中-公开
    哺乳动物细胞因子样多肽-10

    公开(公告)号：EP1719780A3

    公开(公告)日：2006-12-20

    申请号：EP06006241.1

    申请日：1998-11-25

    申请人： ZymoGenetics, Inc.

    发明人： Conklin, Darrell C. ,  Haldeman, Betty A. ,  Grossmann, Angelika

    IPC分类号： C07K16/24 ,  A61K38/00 ,  A61P37/00

    CPC分类号： C07K14/54 ,  A01K67/027 ,  A01K2217/05 ,  A61K38/00 ,  A61K48/00 ,  C07K14/52 ,  C12N2799/021

    摘要： There is provided the use of an antibody, antibody fragment or single chain antibody that selectively binds to a polypeptide comprising an amino acid sequence having at least 80% identity to an IL-20 polypeptide selected from the group consisting of SEQ ID NOs: 2, 4, 12, 13, 19, 20, 25, 26, 34 and 35 for the manufacture of a medicament for the prevention or treatment of an autoimmune disease or condition, or for the prevention or treatment of conditions characterised by improper cell proliferation, cell differentiation or cytokine production.

    摘要翻译： 提供选择性结合多肽的抗体，抗体片段或单链抗体的用途，所述多肽包含与选自SEQ ID NO：2，SEQ ID NO：2，SEQ ID NO： 4,12,13,19,20,25,26,34和35的化合物在制备用于预防或治疗自身免疫性疾病或病症，或用于预防或治疗以不正常细胞增殖为特征的病症的药物中的应用，细胞 分化或细胞因子产生。

    Mammalian cytokine-like polypeptide-10
    5.
    发明公开
    Mammalian cytokine-like polypeptide-10 审中-公开
    CytokinähnlichesPolypeptid-10 ausSäugetieren

    公开(公告)号：EP1719780A2

    公开(公告)日：2006-11-08

    申请号：EP06006241.1

    申请日：1998-11-25

    申请人： ZymoGenetics, Inc.

    发明人： Conklin, Darrell C. ,  Haldeman, Betty A. ,  Grossmann, Angelika

    IPC分类号： C07K16/24 ,  A61K38/00 ,  A61P37/00

    CPC分类号： C07K14/54 ,  A01K67/027 ,  A01K2217/05 ,  A61K38/00 ,  A61K48/00 ,  C07K14/52 ,  C12N2799/021

    摘要： There is provided the use of an antibody, antibody fragment or single chain antibody that selectively binds to a polypeptide comprising an amino acid sequence having at least 80% identity to an IL-20 polypeptide selected from the group consisting of SEQ ID NOs: 2, 4, 12, 13, 19, 20, 25, 26, 34 and 35 for the manufacture of a medicament for the prevention or treatment of an autoimmune disease or condition, or for the prevention or treatment of conditions characterised by improper cell proliferation, cell differentiation or cytokine production.

    摘要翻译： 提供了选择性结合包含与IL-20多肽具有至少80％同一性的氨基酸序列的多肽的抗体，抗体片段或单链抗体的用途，所述IL-20多肽选自SEQ ID NO：2， 4,12,13,19,20,25,26,34和35，用于制备用于预防或治疗自身免疫疾病或病症的药物，或用于预防或治疗以细胞增殖不良为特征的病症 分化或细胞因子产生。