公开(公告)号：EP1478652B1

公开(公告)日：2007-04-25

申请号：EP03742541.0

申请日：2003-02-19

申请人： novosom AG

发明人： DR. ESSLER, Frank ,  Dr. PANZNER, Steffen ,  ENDERT, Gerold

IPC分类号： C07F9/6506 ,  C07K5/062 ,  C07K5/078 ,  C07K5/09 ,  C07C229/16 ,  C07D233/64 ,  A61K9/127 ,  C12N15/88

CPC分类号： A61K9/127 ,  A61K9/1271 ,  A61K9/1272 ,  A61K31/495 ,  A61K31/5375 ,  A61K47/183 ,  A61K47/22 ,  A61K47/24 ,  C07C229/16 ,  C07C229/24 ,  C07D233/64 ,  C07D295/00 ,  C07F9/65067 ,  C07K5/06191 ,  C07K5/0827 ,  C12N15/88 ,  Y10T428/2991

摘要： The invention relates to amphoteric lipids. According to the invention, at least one amphoteric group having an isoelectric point between 4 and 9 is substituted on a membranous or membrane-forming amphiphile. The invention also relates to liposomes containing said compounds.