IMPROVED CONTAINER
    1.
    发明公开
    IMPROVED CONTAINER 有权
    改进的容器

    公开(公告)号:EP2670674A1

    公开(公告)日:2013-12-11

    申请号:EP12701771.3

    申请日:2012-01-26

    摘要: A container (100), comprising a thread (120) arranged around an opening (110) for engaging a corresponding thread (120) of a closure (400), more than four retention members (140) arranged around the opening (110), each retention member (140) having an end-face for abutting a member (510) on an interior surface of the closure (400) to impede unthreading of the closure (400), the retention members (140) being arranged such that a tangent (170) to each end-face of the retention members (140) intersects a plane (160, 350) bisecting the container (100) at an obtuse angle (171), wherein the retention members (140) are arranged in first and second groups, the first group (141, 410) comprising one retention member (140) having an end-face substantially parallel to the plane bisecting the container (100), and the second group (142, 420) comprising two or more retention members (140), the first and second groups being arranged on one side of the plane (160, 350), each in a respective quadrant of the container (100), the teeth of the second group (142, 420) have a first inter-tooth spacing, and a second inter-tooth spacing is provided between an end-face of the retention member of the first group (141, 410) and a first retention member of the second group (142, 420), and the second inter-tooth spacing is larger than the first inter-tooth spacing.

    A CHILD RESISTANT CONTAINER
    8.
    发明公开
    A CHILD RESISTANT CONTAINER 有权
    KINDERSICHERERBEHÄLTER

    公开(公告)号:EP2393723A1

    公开(公告)日:2011-12-14

    申请号:EP10706309.1

    申请日:2010-02-04

    IPC分类号: B65D25/10 B65D43/16 B65D50/04

    摘要: A child resistant container (10) has a container cavity (20) for the receipt of one or more items to be stored therein. The container cavity (20) is defined by a pair of lids (14, 16) which are hingedly connected to one another. Primary lock means (50) includes a first lock assembly on one lid (14, 16) which engages with a second lock assembly on the other lid (14, 16). A primary lock actuation includes an externally open topped pocket (60) formed in the body of said one lid (14, 16). The pocket (60) has a pocket side wall (62) which is resiliently deflectable from a lock position to an unlock position. The pocket (60) is shaped and sized to permit a finger of an operative to enter the pocket (60) to effect deflection of the pocket side wall (62) to its unlock position.

    摘要翻译: 防儿童容器(10)具有用于接收要存储在其中的一个或多个物品的容器腔(20)。 容器空腔(20)由一对盖子(14,16)限定,它们彼此铰接地连接。 主锁定装置(50)包括在一个盖(14,16)上的第一锁定组件,其与另一个盖子(14,16)上的第二锁定组件接合。 主锁定致动包括形成在所述一个盖(14,16)的主体中的外部打开的顶部凹口(60)。 口袋(60)具有可从锁定位置弹性偏转到解锁位置的袋侧壁(62)。 口袋(60)的形状和尺寸被设计成允许操作的手指进入口袋(60)以使口袋侧壁(62)偏转到其解锁位置。

    COMPOSITIONS FOR THE ORAL DELIVERY OF CORTICOSTEROIDS
    9.
    发明公开
    COMPOSITIONS FOR THE ORAL DELIVERY OF CORTICOSTEROIDS 有权
    组合物技术糖皮质激素口服给药

    公开(公告)号:EP2278958A1

    公开(公告)日:2011-02-02

    申请号:EP09746033.1

    申请日:2009-05-07

    IPC分类号: A61K9/48 A61K9/50

    摘要: The present invention provides an oral drug delivery composition comprising a sustained release component which comprises a corticosteroid drug and which is contained within a capsule that has been treated so that the sustained release component is predominately released from the capsule in the intestine following oral administration. The present invention also provides a drug delivery composition for delivering a corticosteroid drug to the intestine comprising: (a) a sustained release component comprising a corticosteroid drug, an alkali- containing ethyicellulose material and an acid; and (b) a delayed release component which substantially prevents release of the sustained release component until the composition reaches the intestine following oral administration. The compositions of the invention are useful for treating inflammatory diseases of the gastrointestinal tract such as Crohn's disease and ulcerative colitis and for treating glomerulonephritis.

    INTRANASAL COMPOSITIONS
    10.
    发明公开
    INTRANASAL COMPOSITIONS 有权
    内源性组合物

    公开(公告)号:EP2214640A1

    公开(公告)日:2010-08-11

    申请号:EP08847366.5

    申请日:2008-11-10

    摘要: The present invention provides a liquid aqueous formulation for the intranasal administration of apomorphine, which comprises: (a) at least about 15 mg/ml of apomorphine; and (b) a solubilising agent selected from (i) at least one polyoxyethylene-polyoxypropylene copolymer (poloxamer); (ii) at least one cyclodextrin; and (iii) at least one cyclodextrin together with chitosan. The formulations of the invention can be used in the treatment/management of Parkinson's disease.

    摘要翻译: 本发明提供了用于鼻内施用阿朴吗啡的液体含水制剂,其包含:(a)至少约15mg / ml的阿扑吗啡; 和(b)选自以下的增溶剂:(i)至少一种聚氧乙烯 - 聚氧丙烯共聚物(泊洛沙姆); (ii)至少一种环糊精; 和(iii)至少一种环糊精与脱乙酰壳多糖一起。 本发明的制剂可用于帕金森病的治疗/管理。