DIAGNOSTIC COMPOSITION
    1.
    发明公开
    DIAGNOSTIC COMPOSITION 失效
    诊断组合物

    公开(公告)号:EP0896547A1

    公开(公告)日:1999-02-17

    申请号:EP97922232.0

    申请日:1997-04-18

    申请人: Diabact AB

    IPC分类号: A61K49 A61K51

    CPC分类号: A61K51/1206 A61K2123/00

    摘要: The present invention relates to a substantially water-free preparation for administering urea in a tablet form, a capsule form or some other solid form. The preparation dissolves very quickly in the stomach. The preparation is used to demonstrate the presence of ammonia in exhalation air, deriving from increased urease activity in the stomach in conjunction with an existing Helicobacter pylori infection.

    PREVENTION OF SUDDEN INFANT DEATH
    2.
    发明公开
    PREVENTION OF SUDDEN INFANT DEATH 失效
    防止本币突然SAUGLINGSTODE

    公开(公告)号:EP1019726A1

    公开(公告)日:2000-07-19

    申请号:EP96938587.1

    申请日:1996-11-06

    申请人: Diabact AB

    IPC分类号: G01N33/569 C12Q1/04 A61K45/00

    摘要: A method for identification of an infant being particularly susceptible to sudden infant death syndrome (SIDS) comprises the determination of an Helicobacter pylori infection in the infant's mother, particularly by detection of antibodies to H. pylori of the IgG type, in a blood sample drawn from the infant's mother or by determination of carbon dioxide formed from urea in the air exhaled from the infant's mother upon oral administration of a challenge dose of urea. Also disclosed is the use of an antibiotic effective against H. pylori for the manufacture of a medicament for administration to mothers and other persons infected by H. pylori and coming into close bodily contact with infants below two years of age, and a method for prevention of SIDS by administration of that antibiotic.

    METHOD AND MEANS FOR DETECTING INFLAMMATORY PROCESSES
    3.
    发明公开
    METHOD AND MEANS FOR DETECTING INFLAMMATORY PROCESSES 审中-公开
    的方法和手段检测抗经营状况

    公开(公告)号:EP1228369A1

    公开(公告)日:2002-08-07

    申请号:EP00975087.8

    申请日:2000-10-24

    申请人: Diabact AB

    摘要: A method of detecting inflammatory processes comprises (a) administering per-orally or per-rectally a composition comprising a diagnostically effective amount of L-[guanido-15N2]-arginine, L-[guanido-15N]-arginine, their mixtures and pharmaceutically acceptable salts thereof, and a pharmaceutically acceptable carrier; (b) collecting a sample of exhaled air, saliva or urine; (c) determining 15NO in the air sample or its transformation products 15N-nitrite and/or 15N-nitrate in the saliva sample or urine. Also disclosed is a corresponding diagnostic composition for use in diagnosing inflammatory processes and a method for its manufacture.

    Prevention of sudden infant death
    5.
    发明公开
    Prevention of sudden infant death 失效
    Vorbeugung desplötzlichenKindstod

    公开(公告)号:EP1121938A2

    公开(公告)日:2001-08-08

    申请号:EP01108549.5

    申请日:1996-11-06

    申请人: Diabact AB

    IPC分类号: A61K45/00 A61K45/06 A61P43/00

    摘要: A use of an antibiotic effective against H. pylori for the manufacture of a medicament for administration to mothers or other persons infected by H. pylori but lacking symptoms and coming into close bodily contact with infants below two years of age, for prevention of SIDS.

    摘要翻译: 使用对幽门螺杆菌有效的抗生素用于制造用于给予感染幽门螺杆菌的母亲或其他人但没有症状并与两岁以下的婴儿紧密身体接触的药物的药物,用于预防小儿免疫球蛋白。

    FENTANYL COMPOSITION FOR THE TREATMENT OF ACUTE PAIN
    6.
    发明公开
    FENTANYL COMPOSITION FOR THE TREATMENT OF ACUTE PAIN 有权
    FENTANYLZUSAMMENSETZUNG急性疼痛在治疗

    公开(公告)号:EP1115384A1

    公开(公告)日:2001-07-18

    申请号:EP99952868.0

    申请日:1999-09-24

    申请人: Diabact AB

    IPC分类号: A61K9/16 A61K31/445

    摘要: A pharmaceutical composition for the treatment of acute pain by sublingual administration is described. The composition comprises an essentially water-free, ordered mixture of fentanyl or a pharmaceutically acceptable salt thereof in the form of microparticles which are adhered to the surface of carrier particles which are substantially larger than the particles of fentanyl, and are essentially water-soluble. In a preferred embodiment, the composition also contains a bioadhesion and/or mucoadhesion promoting agent. The invention also relates to the preparation of the composition, and to the use of the composition for the treatment of acute pain.

    FENTANYL COMPOSITION FOR THE TREATMENT OF ACUTE PAIN
    8.
    发明授权
    FENTANYL COMPOSITION FOR THE TREATMENT OF ACUTE PAIN 有权
    FENTANYLZUSAMMENSETZUNG急性疼痛在治疗

    公开(公告)号:EP1115384B1

    公开(公告)日:2003-08-27

    申请号:EP99952868.0

    申请日:1999-09-24

    申请人: Diabact AB

    IPC分类号: A61K9/16 A61K31/445 A61P25/04

    摘要: A pharmaceutical composition for the treatment of acute pain by sublingual administration is described. The composition comprises an essentially water-free, ordered mixture of fentanyl or a pharmaceutically acceptable salt thereof in the form of microparticles which are adhered to the surface of carrier particles which are substantially larger than the particles of fentanyl, and are essentially water-soluble. In a preferred embodiment, the composition also contains a bioadhesion and/or mucoadhesion promoting agent. The invention also relates to the preparation of the composition, and to the use of the composition for the treatment of acute pain.

    DIAGNOSTIC COMPOSITION
    9.
    发明授权
    DIAGNOSTIC COMPOSITION 失效
    诊断组合物

    公开(公告)号:EP0896547B1

    公开(公告)日:2002-06-26

    申请号:EP97922232.0

    申请日:1997-04-18

    申请人: Diabact AB

    IPC分类号: A61K49/00

    CPC分类号: A61K51/1206 A61K2123/00

    摘要: The present invention relates to a substantially water-free preparation for administering urea in a tablet form, a capsule form or some other solid form. The preparation dissolves very quickly in the stomach. The preparation is used to demonstrate the presence of ammonia in exhalation air, deriving from increased urease activity in the stomach in conjunction with an existing Helicobacter pylori infection.