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    DIGITAL PHASE LOCKED LOOP DEVICE AND METHOD IN WIRELESS COMMUNICATION SYSTEM
    3.
    发明公开
    DIGITAL PHASE LOCKED LOOP DEVICE AND METHOD IN WIRELESS COMMUNICATION SYSTEM 有权
    数字设备和方法，一个无线通信系统的锁相环

    公开(公告)号：EP2608413A2

    公开(公告)日：2013-06-26

    申请号：EP11818426.6

    申请日：2011-08-19

    申请人： Samsung Electronics Co., Ltd ,  Konkuk University Industrial Cooperation Corp.

    发明人： LEE, Kang-Yoon ,  PU, Young-Gun ,  PARK, An-Soo ,  PARK, Joon-Sung ,  LEE, Jae-Sup

    IPC分类号： H03L7/089

    CPC分类号： H03L7/089 ,  H03L7/085 ,  H03L7/18 ,  H03L2207/50

    摘要： A digital Phase Locked Loop (PLL) in a wireless communication system is provided. The PLL includes a Digitally Controlled Oscillator (DCO), a divider, a Phase Frequency Detector (PFD), a Time to Digital Converter (TDC), a delay comparator, and a level scaler. The DCO generates a frequency signal depending on an input Digital Tuning Word (DTW). The divider divides the frequency signal at an integer ratio. The PFD generates a signal representing a phase difference between a divided frequency signal and a reference signal. The TDC measures a time interval of the phase difference using the signal representing the phase difference. The delay comparator calculates a time interval in the case where rising edges coincide from values measured by the TDC. The level scaler generates a DTW that operates the DCO using a digital code representing the time interval.

    USE OF HADES AS TUMOR SUPPRESSOR TARGET
    4.
    发明公开
    USE OF HADES AS TUMOR SUPPRESSOR TARGET 审中-公开
    VERFAHRENFÜRHADES ALSTUMORUNTERDRÜCKUNGSZIEL

    公开(公告)号：EP2561885A2

    公开(公告)日：2013-02-27

    申请号：EP11772243.9

    申请日：2011-04-21

    申请人： Konkuk University Industrial Cooperation Corp.

    发明人： AN, Sungkwan ,  JUNG, Jin Hyuk ,  LEE, Jae Ho ,  BAE, Seunghee

    IPC分类号： A61K38/16 ,  A61K38/10 ,  A61K39/395 ,  A61P35/00

    CPC分类号： A61K38/17 ,  A61K38/53 ,  C07K16/18

    摘要： The present invention relates to a new use of Hades as a tumor suppressor target, more particularly to a composition for suppressing tumor comprising an expression or action inhibitor of Hades protein having an amino acid sequence of SEQ ID NO: 2 as an effective ingredient.
    The present inventors have found that the overexpressed Hades protein interacts with p53 to inhibit the exonuclear mechanism of p53 and the knowdown of Hades induces increase in the expression of p53, demonstrating that Hades is a negative regulator to p53. Therefore, it would be understood that the inhibition of Hades overexpressed in tumor cells contributes to tumor-supressive effects of p53. The drug candidates capable of modulating the expression of the Hades protein, inhibiting the actions of the Hades protein or inhibiting interecation between Hades and p53 are considered a promising anticancer drug.

    摘要翻译： 本发明涉及Hades作为肿瘤抑制靶的新用途，更具体地涉及包含具有SEQ ID NO：2的氨基酸序列的Hades蛋白的表达或作用抑制剂作为有效成分的抑制肿瘤的组合物。 本发明人已经发现，过表达的Hades蛋白与p53相互作用以抑制p53的外核机制，并且Hades的知识诱导p53表达增加，表明Hades是p53的负调节因子。 因此，可以理解，在肿瘤细胞中过表达的Hades的抑制有助于p53的肿瘤抑制作用。 能够调节Hades蛋白表达，抑制Hades蛋白的作用或抑制Hades和p53之间的相互作用的候选药物被认为是有希望的抗癌药物。

    SYSTEM FOR CONTROLLING THE FORCE REBALANCE USING AUTOMATIC GAIN CONTROLLING LOOP AND METHOD FOR THE SAME
    6.
    发明公开
    SYSTEM FOR CONTROLLING THE FORCE REBALANCE USING AUTOMATIC GAIN CONTROLLING LOOP AND METHOD FOR THE SAME 审中-公开
    系统对于使用自动增益控制环路及其方法控KRAFTNEUAUSGLEICHS

    公开(公告)号：EP2235476A2

    公开(公告)日：2010-10-06

    申请号：EP08712196.8

    申请日：2008-01-25

    申请人： Konkuk University Industrial Cooperation Corp.

    发明人： SUNG, Sang-Kyung ,  SUNG, Woon-Tahk

    IPC分类号： G01C19/56

    CPC分类号： G01C19/56

    摘要： The present invention relates to a force rebalance control system and method using an automatic gain control loop, which are configured to perform the force rebalance feedback control of a vibratory gyroscope using the automatic gain control loop for controlling the velocity signal of a mass body. Accordingly, the present invention is advantageous in that a conventional digital circuit, which is complicated and sensitive to noise, can be implemented using a simple analog circuit, and the present invention can be extended and applied to general-purpose vibratory gyroscopes or various sensor fields, such as those of an inertial sensor, a pressure sensor, and a temperature sensor, as well as micro-gyroscopes. Further, a force rebalance control system using an automatic gain control loop according to the present invention is applied to various sensors, thus improving performance, such as the dynamic range, bandwidth, and linearity of the sensors.