公开(公告)号：EP4381441A1

公开(公告)日：2024-06-12

申请号：EP22768999.9

申请日：2022-07-27

申请人： Nantstudios, LLC ,  Nant Holdings IP, LLC

发明人： SOON-SHIONG, Patrick ,  MARSHALL, Gary ,  HEINRICHS, Keaton ,  WIACEK, John ,  WITCHEY, Nicholas James

IPC分类号： G06Q10/06

CPC分类号： G06Q10/101

公开(公告)号：EP3542290B1

公开(公告)日：2024-01-03

申请号：EP17804385.7

申请日：2017-11-09

发明人： NIAZI, Kayvan ,  RABIZADEH, Shahrooz ,  WITCHEY, Nicholas J.

IPC分类号： G16B5/00 ,  G16B5/20 ,  G16H50/50

公开(公告)号：EP3614277B1

公开(公告)日：2022-08-03

申请号：EP19203605.1

申请日：2013-05-24

发明人： Soon-Shiong, Patrick

IPC分类号： G06F17/00

公开(公告)号：EP3735984A1

公开(公告)日：2020-11-11

申请号：EP20179172.0

申请日：2017-05-26

申请人： Etubics Corporation ,  Nant Holdings IP, LLC ,  NantCell, Inc.

发明人： JONES, Frank R ,  RICE, Adrian ,  SOON-SHIONG, Patrick ,  RABIZADEH, Shahrooz ,  NIAZI, Kayvan

IPC分类号： A61K39/00 ,  C12N15/86 ,  C07K14/705 ,  C07K14/54 ,  C07K14/715

摘要： In certain embodiments, methods and compositions are provided for generating immune responses against tumor neo-antigens or neo-epitopes. In particular embodiments there may be provided methods for constructing and producing recombinant adenovirus-based vector vaccines containing nucleic acid sequences encoding tumor neo-antigens and neo-epitopes that allow for vaccinations in individuals with preexisting immunity to adenovirus. In additional embodiments, methods and compositions are provided for the treatment of cancer using immunotherapy based on recombinant adenovirus-based vectors combined with engineered natural killer cells. In some embodiments, the methods and compositions further comprises a nucleic acid encoding for an immunological fusion partner.

公开(公告)号：EP2856335B1

公开(公告)日：2020-03-11

申请号：EP13794602.6

申请日：2013-05-24

申请人： Nant Holdings IP, LLC

发明人： SOON-SHIONG, Patrick

IPC分类号： G06F16/00

公开(公告)号：EP3579885A1

公开(公告)日：2019-12-18

申请号：EP18751027.6

申请日：2018-02-08

申请人： Nantcell, Inc. ,  Nant Holdings IP, LLC

发明人： RABIZADEH, Shahrooz ,  NIAZI, Kayvan ,  SOON-SHIONG, Patrick

IPC分类号： A61K48/00 ,  A61K31/7068 ,  A61K31/675 ,  A61K31/513 ,  A61P35/00

公开(公告)号：EP3516829A1

公开(公告)日：2019-07-31

申请号：EP17854121.5

申请日：2017-09-26

申请人： Nant Holdings IP, LLC ,  Packetfabric, LLC

发明人： CHARNOCK, William ,  TURKBERGEN, Richard ,  SOON-SHIONG, Patrick

IPC分类号： H04L12/46 ,  H04L29/08 ,  H04L29/06

公开(公告)号：EP3493836A1

公开(公告)日：2019-06-12

申请号：EP17837603.4

申请日：2017-08-02

申请人： Nantcell, Inc. ,  Nant Holdings IP, LLC

发明人： SOON-SHIONG, Patrick ,  NIAZI, Kayvan

IPC分类号： A61K39/00 ,  A61K48/00

公开(公告)号：EP3277678A1

公开(公告)日：2018-02-07

申请号：EP16774366.5

申请日：2016-04-01

申请人： NantBioScience, Inc. ,  Nantomics, LLC ,  Nant Holdings IP, LLC

发明人： RABIZADEH, Shahrooz ,  KAYVAN, Niazi ,  BUZKO, Sasha ,  WEINGARTEN, Paul ,  MCFARLANE, Heather ,  JUNCKER-JENSEN, Anna ,  GOLOVATO, Justin ,  SOON-SHIONG, Patrick ,  TAO, Chunlin ,  HO, David

IPC分类号： C07D417/12 ,  C07D417/14 ,  A61K31/427 ,  A61K31/4725 ,  A61P35/00

摘要： Compounds and compositions are presented that inhibit K-ras, and especially mutant K-ras. Certain compounds preferentially or even selectively inhibit specific forms of mutant K-Ras, and particularly the G12D mutant form.

公开(公告)号：EP3195167A4

公开(公告)日：2017-11-29

申请号：EP14856039

申请日：2014-09-26

申请人： NANT HOLDINGS IP LLC

发明人： SOON-SHIONG PATRICK

IPC分类号： G06F19/28 ,  G06F19/00

CPC分类号： G06F19/3425 ,  G06F19/28 ,  G06F19/345 ,  G16H50/20 ,  G16H80/00

摘要： The inventive subject matter provides apparatus, systems, and methods that improve on the pace of discovering new practical information based on large amounts of datasets collected. In most cases, anomalies from the datasets are automatically identified, flagged, and validated by a cross-validation engine. Only validated anomalies are then associated with a subject matter expert who is qualified to take action on the anomaly. In other words, the inventive subject matter bridges the gap between the overwhelming amount of scientific data which can now be harvested and the comparatively limited amount analytical resources available to extract practical information from the data. Practical information can be in the form of trends, patterns, maps, hypotheses, or predictions, for example, and such practical information has implications in medicine, in environmental sciences, entertainment, travel, shopping, social interactions, or other areas.