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公开(公告)号:EP4414372A3
公开(公告)日:2024-10-02
申请号:EP24179515.2
申请日:2014-03-17
摘要: Substrates are provided that include compounds suitable for detecting the activity of an enzyme such as a lysosomal storage enzyme where the substrates include: a sugar moiety; a linker moiety allowing the conjugation of sugar moiety with the remaining structure of the substrate; and two or more fatty acid chains or derivatives thereof at least one of which is sufficiently structured to provide improved solubility in aqueous or organic solvent systems. Also provided are methods for using substrates for detecting enzymatic activity using the inventive substrates.
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公开(公告)号:EP3937995B1
公开(公告)日:2024-08-07
申请号:EP20770976.7
申请日:2020-03-13
IPC分类号: A61L29/06 , C09D133/26 , A61L29/08 , A61L29/14
CPC分类号: C09D133/26 , C08L2312/0620130101 , A61L29/06 , A61L29/141 , A61L29/085 , A61L29/145
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公开(公告)号:EP3620521B1
公开(公告)日:2024-05-29
申请号:EP19185730.9
申请日:2015-09-04
IPC分类号: C12N15/85 , C12N15/86 , A61K48/00 , C12N15/113 , C12N15/867 , C07K14/805 , C12N9/22 , A61P7/06
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公开(公告)号:EP3988631B1
公开(公告)日:2023-11-22
申请号:EP21203170.2
申请日:2017-06-13
发明人: CHIU, Daniel, T , YU, Jiangbo , RONG, Yu , WU, Changfeng
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公开(公告)号:EP3955242B1
公开(公告)日:2023-09-20
申请号:EP21200989.8
申请日:2015-08-26
IPC分类号: G10K11/34 , G10K11/30 , A61B17/225 , G10K15/00 , A61B17/22
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公开(公告)号:EP3337891B1
公开(公告)日:2023-06-07
申请号:EP16839809.7
申请日:2016-08-12
发明人: COHEN, Peter A. , GENDLER, Sandra J. , PATHANGEY, Latha B. , MCCURRY, Dustin B. , GORMAN, Jessica E. , DISIS, Mary L.
IPC分类号: C12N5/071 , C12N5/0783 , C07K16/28 , A61K39/00
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公开(公告)号:EP3044605B1
公开(公告)日:2022-11-16
申请号:EP14767140.8
申请日:2014-09-03
发明人: WANG, Jinnan , BOERNERT, Peter , YUAN, Chun
IPC分类号: G01R33/54 , G01R33/563
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