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公开(公告)号：EP3228348A1
公开(公告)日：2017-10-11
申请号：EP17165029.4
申请日：2017-04-05
申请人： Covidien LP
发明人： McPeak, Thomas
CPC分类号： A61B8/0841 , A61B8/481 , A61B90/39 , A61B2090/3925 , A61K49/223 , A61L29/145 , A61L29/146 , A61L29/148 , A61M25/0108 , A61M25/10 , A61M2025/1031 , A61M2025/1075 , A61M2025/1088 , A61M2025/1093 , A61M2202/0225
摘要： A medical device includes a structural element comprising an outer surface and a material on the outer surface of the structural element. The material defines void spaces containing a gas entrained within the void spaces. The material, upon contact with physiological fluid, is configured to release the gas in an amount sufficient for the gas to be imaged by ultrasound.
摘要翻译： 医疗装置包括结构元件，该结构元件包括外表面和结构元件的外表面上的材料。 该材料限定了包含在空隙空间内夹带的气体的空隙空间。 一旦与生理流体接触，该材料被构造成释放足以使气体通过超声成像的量的气体。
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公开(公告)号：EP3164166A1
公开(公告)日：2017-05-10
申请号：EP15733452.5
申请日：2015-07-01
申请人： Wellinq Medical B.V.
CPC分类号： A61L29/145 , A61L29/06 , A61L29/085 , A61L29/106 , A61L2400/10 , A61L2400/12 , A61L2420/02 , A61L2420/08 , C08L39/06
摘要： A method for providing a hydrogel coating on a polymeric substrate of a medical device involves a priming step in which the polymeric substrate is contacted with a priming solution, and a grafting step following the priming step in which the polymeric substrate is contacted with a grafting solution, thereby providing a polymeric substrate of a medical device having a hydrogel coating.
摘要翻译： 本发明涉及一种用于在医疗器械的聚合物基材上提供水凝胶涂层的方法，其包括：引发步骤，其中使聚合物基材与包含1至30wt％的平均分子量为1至30的聚乙二醇二丙烯酸酯 重量为300至750 Da; 在引发步骤之后的接枝步骤，其中聚合物基材与接枝溶液接触，由此提供具有水凝胶涂层的医疗装置的聚合物基材。
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3.发明授权HYDROPHILIC COATING THAT REDUCES PARTICLE DEVELOPMENT ON ESTER-LINKED POLY(ESTER-BLOCK-AMIDE) 有权HYDROPHILE BESCHICHTUNG ZUR REDUZIERUNG DER TEILCHENENTWICKLUNG AUF ESTER-VERKNÜPFTEMPOLY（ESTER-BLOCK-AMID）
公开(公告)号：EP2398522B1
公开(公告)日：2017-01-11
申请号：EP10705042.9
申请日：2010-02-11
CPC分类号： A61L29/085 , A61L29/14 , A61L29/145 , Y10T428/265 , Y10T428/31786
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4.发明公开MEDICAL DEVICE HYBRID POLYMERIC STRUCTURES AND COATINGS WITH IMPROVED LUBRICITY AND DURABILITY 审中-公开杂化聚合物结构的医疗器械和改进了油容量和稳定性涂料
公开(公告)号：EP3096805A1
公开(公告)日：2016-11-30
申请号：EP15704876.0
申请日：2015-01-20
发明人： ADENUSI, Adegbola , ROHL, James P. , WULFMAN, David R. , DELANEY, JR, Joseph T. , AREMU, Adeniyi
IPC分类号： A61L29/06 , A61L29/08 , A61L29/14 , A61L31/06 , A61L31/10 , A61L31/14 , A61L29/04 , A61L31/04 , A61N1/36
CPC分类号： A61M39/08 , A61L29/041 , A61L29/06 , A61L29/085 , A61L29/145 , A61L29/146 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/145 , A61L31/146 , A61M39/00 , A61N1/0541 , A61N1/056 , B32B1/08 , B32B5/02 , B32B5/022 , B32B27/08 , B32B27/12 , B32B2262/0238 , B32B2535/00 , D01D5/0023 , D01D5/0076 , D01D5/0084 , D01D5/0985 , Y10T428/1372 , C08L71/02 , C08L39/06 , C08L75/04 , C08L83/04
摘要： A method for making a tubular medical device having a hybrid polymeric structure includes forming a first layer comprising a non-woven fibrous matrix made of a first polymeric material and forming a second layer comprising a second polymeric material about the first layer such that at least a portion of the second polymeric material of the second layer embeds into at least a portion of the first polymeric material of the first layer.
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公开(公告)号：EP2709711B1
公开(公告)日：2016-11-23
申请号：EP12785593.0
申请日：2012-05-17
申请人： Vatrix Medical, Inc.
IPC分类号： A61L29/06 , A61L29/08 , A61L29/14 , A61L29/16 , A61M25/10 , A61K31/11 , A61K31/70 , A61K47/32
CPC分类号： A61K47/32 , A61K31/11 , A61K31/7024 , A61L29/06 , A61L29/085 , A61L29/145 , A61L29/16 , A61L2300/102 , A61M25/1011 , A61M25/104 , A61M2025/105 , A61M2025/1052 , A61M2025/1075 , A61M2025/1086 , A61M2025/1097 , F04C2270/0421 , A61K2300/00 , C08L75/04 , C08L29/04
摘要： A coated balloon device for stabilizing a section of a blood vessel in a living subject is disclosed. The coating layer of the coated balloon comprises a phenolic compound having a plurality of phenolic groups connected to form a hydrophobic core with peripheral phenolic hydroxyl groups. The coating layer of the coated balloon may contain a hydrophilic polymer to facilitate the release of the phenolic compound. The balloon in general is made of a compliant polymer for atraumatic contact with the blood vessel. In some embodiments, the coating of the coated balloon device further comprises a hydrophilic undercoat layer between the balloon and the coating layer. In some embodiments, the coated balloon device further comprises a sacrificial top coating that dissolves upon delivery into the section of the blood vessel and comprises a hydrophilic composition including sugar, sugar derivatives, or a combination thereof.
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6.发明授权MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME. 有权多臂大分子单体的聚合材料和隐形眼镜SO
公开(公告)号：EP2443483B1
公开(公告)日：2016-03-23
申请号：EP10724980.7
申请日：2010-06-14
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公开(公告)号：EP2968684A1
公开(公告)日：2016-01-20
申请号：EP13716524.7
申请日：2013-03-15
发明人： STANKUS, John , TROLLSAS, Mikael , HOSSAINY, Syed
CPC分类号： A61L29/085 , A61L29/145 , A61L29/16 , C08L67/04 , C08L5/08 , C08L5/04
摘要： The present invention relates to systems for and corresponding methods of delivering a therapeutic agent to a vessel wall of a body lumen by providing a compound capable of being crosslinked after intraluminal release onto a vessel wall so that the therapeutic agent is temporarily retained at the site of delivery by the crosslinked compound.
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8.发明授权CHITOSAN HYDROGEL DERIVATIVES AS A COATING AGENT WITH BROAD SPECTRUM OF ANTIMICROBIAL ACTIVITIES 有权具有广谱抗菌CHITOSANHYDROGELDERVIATE AS种衣剂
公开(公告)号：EP2454286B1
公开(公告)日：2015-12-16
申请号：EP09847352.3
申请日：2009-07-13
CPC分类号： A61L27/34 , A61K8/042 , A61K8/736 , A61L27/20 , A61L27/52 , A61L27/54 , A61L29/043 , A61L29/085 , A61L29/145 , A61L31/042 , A61L31/10 , A61L31/145 , A61L31/16 , A61L2300/232 , A61L2300/404 , A61Q19/00 , C08B37/003 , C08F290/10 , C08G81/00 , C08J3/075 , C08J3/24 , C08J3/28 , C08J2305/08 , G02B1/043 , C08L1/00 , C08F220/28 , C08L5/08
摘要： The present invention relates to water soluble quaternized chitosan derivatives which form hydrogel matrix with broad antimicrobial properties for the protection and coating of medical device. Hydrogel is attractive as an antimicrobial coating since its hydrophilicity intrinsically prevents the reversible nonspecific attachment of microbes. In order to achieve hydrogel formation, quaternized chitosan can be grafted with polymerizable groups, especially photocrosslinkable groups, such as methacrylates, PEG derivatives and be converted into hydrogels through a thermal or UV polymerization process. Hydrogels are hydrated cross-linked polymeric systems that contain water in an equilibrium state forming cushion water shield. The present invention is widely used in many medical devices. This invention describes the formation of novel hydrogels based on quaternized ammonium chitosan derivatives which has been grafted with photocrosslinkable groups, hence providing hydrogels as antimicrobial water shield coating agent.
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公开(公告)号：EP2407479B1
公开(公告)日：2014-04-16
申请号：EP10750643.8
申请日：2010-02-12
发明人： NAGAI, Yusuke , YOKOI, Hidenori , UESUGI, Koji , NARUSE, Keiji
CPC分类号： C07K7/08 , A61K8/64 , A61K9/0048 , A61K9/06 , A61K38/10 , A61K47/42 , A61L15/60 , A61L27/227 , A61L27/52 , A61L29/145 , A61L31/10 , A61L31/145 , A61Q5/00 , A61Q19/00 , B01J20/28047 , C10M173/02 , C12N5/0068 , C12N5/0656 , C12N5/0658 , C12N2533/50
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公开(公告)号：EP2407479A9
公开(公告)日：2012-06-13
申请号：EP10750643.8
申请日：2010-02-12
发明人： NAGAI, Yusuke , YOKOI, Hidenori , UESUGI, Koji , NARUSE, Keiji
CPC分类号： C07K7/08 , A61K8/64 , A61K9/0048 , A61K9/06 , A61K38/10 , A61K47/42 , A61L15/60 , A61L27/227 , A61L27/52 , A61L29/145 , A61L31/10 , A61L31/145 , A61Q5/00 , A61Q19/00 , B01J20/28047 , C10M173/02 , C12N5/0068 , C12N5/0656 , C12N5/0658 , C12N2533/50
摘要： Provided are a peptide gel with practically sufficient mechanical strength and a self-assembling peptide capable of forming the peptide gel. The self-assembling peptide is formed of the following amino acid sequence: a 1 b 1 c 1 b 2 a 2 b 3 db 4 a 3 b 5 c 2 b 6 a 4 where: a 1 to a 4 each represent a basic amino acid residue; b 1 to b 6 each represent an uncharged polar amino acid residue and/or a hydrophobic amino acid residue, provided that at least five thereof each represent a hydrophobic amino acid residue; c 1 and c 2 each represent an acidic amino acid residue; and d represents a hydrophobic amino acid residue.
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