公开(公告)号：EP3253424A1

公开(公告)日：2017-12-13

申请号：EP16711333.1

申请日：2016-02-03

申请人： Matoke Holdings Limited

发明人： PATTON, Thomas ,  BRENNAN, James ,  STAPLES, Ian ,  ELDER, Iain ,  CALLAGHAN, Annette ,  DRYDEN, Matthew ,  BARRETT, John, Reginald ,  KERSHAW, David ,  SALIB, Rami

IPC分类号： A61L15/24 ,  A61L15/26 ,  A61L15/40 ,  A61L15/42 ,  A61L15/46

CPC分类号： D01F4/00 ,  A01N25/34 ,  A01N63/00 ,  A61K9/70 ,  A61K38/443 ,  A61K47/46 ,  A61L15/24 ,  A61L15/26 ,  A61L15/38 ,  A61L15/40 ,  A61L15/425 ,  A61L15/44 ,  A61L15/46 ,  A61L2300/11 ,  A61L2300/232 ,  A61L2300/254 ,  A61L2300/404 ,  A61L2400/12 ,  C12Y101/03004 ,  D01F9/00 ,  D10B2509/022 ,  C08L29/04 ,  C08L39/04 ,  C08L71/02

摘要： Fibers for generating antimicrobial activity are described. The fibers comprise an enzyme that is able to convert a substrate to release hydrogen peroxide, and an unrefined natural substance that includes a substrate for the enzyme, wherein the enzyme is additional to any enzyme activity able to convert the substrate to release hydrogen peroxide that may be present in the unrefined natural substance. In the presence of sufficient free water, the enzyme converts the substrate to release hydrogen peroxide, which is effective against a wide range of microbes. Wound dressings and compositions comprising the fibers are also described, as is use of the fibers, wound dressings and compositions, particularly for wound healing.

公开(公告)号：EP1799276B1

公开(公告)日：2017-05-03

申请号：EP05792097

申请日：2005-10-07

申请人： NGEN PHARMACEUTICALS N V

发明人： LEKHRAM CHANGOER ,  VAN DEN BOSCH WILLEM FREDERIK ,  MEIJERINK HENDRIK JAN CORNELIS

IPC分类号： A61L26/00

CPC分类号： A61L26/0004 ,  A61L15/18 ,  A61L15/44 ,  A61L26/0076 ,  A61L2300/11 ,  A61L2300/412

公开(公告)号：EP1874244B1

公开(公告)日：2016-08-24

申请号：EP05825727.0

申请日：2005-11-14

申请人： Opremcak, E. Mitchel

发明人： Opremcak, E. Mitchel

IPC分类号： A61F13/00 ,  A61F13/02 ,  A61L15/16

CPC分类号： A61K33/40 ,  A61F13/0203 ,  A61K31/327 ,  A61L15/44 ,  A61L2300/11

公开(公告)号：EP2890406A4

公开(公告)日：2016-04-13

申请号：EP13832398

申请日：2013-08-30

申请人： GORE & ASS

发明人： BROWN TIFFANY J ,  LAFLEUR ADAM S ,  MAZICH KENNETH ,  TOWLER JEFFREY C ,  ZHANG JI

IPC分类号： A61L27/18 ,  A61K31/593 ,  A61K31/715 ,  A61L15/26 ,  A61L15/44 ,  A61L15/64 ,  A61L27/54 ,  A61L27/58

CPC分类号： A61K31/765 ,  A61K31/593 ,  A61K31/715 ,  A61L15/26 ,  A61L15/44 ,  A61L15/64 ,  A61L27/18 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/11 ,  A61L2300/114 ,  A61L2300/404 ,  Y10T428/2982 ,  A61K2300/00 ,  C08L67/04

摘要： Materials capable of delivering stabilized free radicals to targeted treatment sites. The materials comprise semi-crystalline, hydrolytically degradable polymers that are subjected to ionizing radiation to create stabilized free radicals therein. Upon exposure to oxygen containing aqueous media, the materials generate reactive oxidative species which are useful in biological processes.

摘要翻译： 材质能够提供稳定的自由基，有针对性的治疗点。 所述材料包括半结晶，可水解降解的聚合物并经受电离辐射以在其中产生稳定的自由基。 在暴露于含氧的水介质中，材料产生反应性氧化性物质哪些是在生物过程中是有用的。

公开(公告)号：EP2528630B1

公开(公告)日：2016-03-30

申请号：EP11701493.6

申请日：2011-01-20

申请人： BASF SE

发明人： BRAIG, Volker ,  DANIEL, Thomas

IPC分类号： A61L15/18 ,  A61L15/46

CPC分类号： A61L15/18 ,  A61L15/46 ,  A61L2300/102 ,  A61L2300/11

公开(公告)号：EP2398508A4

公开(公告)日：2014-03-19

申请号：EP10744319

申请日：2010-02-18

申请人： QUICK MED TECHNOLOGIES INC

发明人： TOREKI WILLIAM ,  LEANDER SUSAN ,  OLDERMAN GERALD M

IPC分类号： A61L15/60 ,  A61L15/46

CPC分类号： C08F8/00 ,  A01N37/02 ,  A01N59/00 ,  A61K33/40 ,  A61K47/58 ,  A61K2800/56 ,  A61L15/24 ,  A61L15/44 ,  A61L15/46 ,  A61L15/60 ,  A61L2300/11 ,  A61L2300/404 ,  A61L2300/802 ,  C08L33/08 ,  C08L33/10 ,  Y10T428/1324

摘要： This invention pertains to a polymeric composition and an antimicrobial composition, each comprising a superabsorbent polymer (SAP), such as used in diapers and sanitary napkins, and peroxide. The superabsorbent material can be made by the process of treating a preformed SAP, such as a crosslinked polyacrylate salt, with a treatment solution comprising hydrogen peroxide dissolved in water, followed by drying. The resulting superabsorbent material has strong antimicrobial activity. Optionally, the treatment solution may also contain a metal salt, including those of zinc, zirconium, and magnesium.

公开(公告)号：EP2252333A4

公开(公告)日：2013-07-10

申请号：EP09709900

申请日：2009-02-13

申请人： OXYGEN BIOTHERAPEUTICS INC ,  UNIV VIRGINIA COMMONWEALTH

发明人： WARD KEVIN R ,  DIEGELMANN ROBERT ,  SPIESS BRUCE ,  HUVARD GARY S ,  SANDHU GURBHAGAT S ,  BOWLIN GARY ,  STERN CHRIS

IPC分类号： A61L15/00

CPC分类号： A61L15/20 ,  A61F13/00063 ,  A61F13/069 ,  A61F2013/00153 ,  A61F2013/00157 ,  A61F2013/0017 ,  A61F2013/00246 ,  A61F2013/00285 ,  A61F2013/00468 ,  A61F2013/00519 ,  A61F2013/00646 ,  A61F2013/00906 ,  A61F2013/00919 ,  A61K9/1271 ,  A61K33/00 ,  A61L15/44 ,  A61L2300/11 ,  A61L2300/114 ,  A61L2300/608

公开(公告)号：EP2252333A2

公开(公告)日：2010-11-24

申请号：EP09709900.6

申请日：2009-02-13

申请人： Oxygen Biotherapeutics, Inc. ,  Virginia Commonwealth University

发明人： WARD, Kevin, R. ,  DIEGELMANN, Robert ,  SPIESS, Bruce ,  HUVARD, Gary, S. ,  SANDHU, Gurbhagat, S. ,  BOWLIN, Gary ,  STERN, Chris

IPC分类号： A61L15/00

CPC分类号： A61L15/20 ,  A61F13/00063 ,  A61F13/069 ,  A61F2013/00153 ,  A61F2013/00157 ,  A61F2013/0017 ,  A61F2013/00246 ,  A61F2013/00285 ,  A61F2013/00468 ,  A61F2013/00519 ,  A61F2013/00646 ,  A61F2013/00906 ,  A61F2013/00919 ,  A61K9/1271 ,  A61K33/00 ,  A61L15/44 ,  A61L2300/11 ,  A61L2300/114 ,  A61L2300/608

摘要： This invention provides articles of manufacture and bandages comprising compartments and layers comprising oxygen and other therapeutic gas storage forms and perfluorocarbons. This invention also provides for methods of delivering oxygen and other therapeutic gases to a tissue in a subject comprising a administering to the tissue a composition comprising a perf luorocarbon and a oxygen or therapeutic gas storage form, so as to thereby deliver oxygen or the therapeutic gas to the tissue.

公开(公告)号：EP1893187A2

公开(公告)日：2008-03-05

申请号：EP06741316.1

申请日：2006-06-13

申请人： Flen Pharma N.V.

发明人： VAN DEN PLAS, Dave ,  DE SMET, Kris ,  SOLLIE, Philippe

IPC分类号： A61K31/055 ,  A61K38/44 ,  A61K31/05 ,  A61L26/00 ,  C11D3/00 ,  C11D3/386 ,  A01N63/00

CPC分类号： A61L26/008 ,  A01N31/16 ,  A01N35/04 ,  A01N37/40 ,  A61K31/05 ,  A61K33/40 ,  A61K38/44 ,  A61K38/443 ,  A61L26/0066 ,  A61L2300/11 ,  A61L2300/216 ,  A61L2300/254 ,  A61L2300/45 ,  A61L2300/802 ,  C12Y101/03004 ,  C12Y111/01007 ,  A01N37/46 ,  A01N59/00 ,  A01N59/16 ,  A01N61/00 ,  A01N2300/00 ,  A61K2300/00

摘要： The present invention discloses a class of compounds which have an enhancing effect on peroxidase based antimicrobial compositions. The invention relates to pharmaceutical compositions for prolonged topical use comprising enhancing agents such as methoxyphenols and substituted benzylaldehydes. Examples hereof are respectively guaiacol and vanillin.

公开(公告)号：EP1244476A2

公开(公告)日：2002-10-02

申请号：EP00990393.1

申请日：2000-12-29

申请人： Acrymed

发明人： GIBBINS, Bruce, L. ,  HOPMAN, Lance, D.

IPC分类号： A61L15/44 ,  A61L15/46 ,  A61L15/38 ,  A61L15/22 ,  A61L26/00

CPC分类号： A61K33/00 ,  A61K9/7007 ,  A61K33/08 ,  A61K33/10 ,  A61K33/40 ,  A61L15/225 ,  A61L15/38 ,  A61L15/425 ,  A61L15/44 ,  A61L15/46 ,  A61L26/0052 ,  A61L26/0066 ,  A61L26/0071 ,  A61L26/0085 ,  A61L2300/11 ,  C08L5/12 ,  C08L33/26 ,  C08L5/14

摘要： The present invention comprises methods and compositions for delivery devices. More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide having oxygen and optionally active agents incorporated therein. The matrix may be formed into any desired shape for treatment of compromised tissue or for delivery of oxygen to a localized environment.