公开(公告)号：EP2437737B1

公开(公告)日：2018-08-29

申请号：EP10724790.0

申请日：2010-06-07

申请人： Septeos

发明人： TESSE, Nicolas

IPC分类号： A61K31/015 ,  A61K31/045 ,  A61K31/08 ,  A61K31/11 ,  A61K31/22 ,  A61K31/352 ,  A61K31/37 ,  A61K45/06 ,  A61P31/04

CPC分类号： A61K9/0014 ,  A61K31/015 ,  A61K31/045 ,  A61K31/08 ,  A61K31/11 ,  A61K31/22 ,  A61K31/352 ,  A61K31/37 ,  A61K45/06 ,  A61L29/16 ,  A61L2300/216 ,  A61L2300/404 ,  A61L2300/45 ,  A61K2300/00

公开(公告)号：EP3360586A1

公开(公告)日：2018-08-15

申请号：EP18161363.9

申请日：2009-04-17

申请人： Micell Technologies, Inc.

发明人： MCCLAIN, James, B. ,  TAYLOR, Douglas

IPC分类号： A61L31/14 ,  A61L31/16 ,  A61F2/91

CPC分类号： A61L31/148 ,  A61F2/91 ,  A61F2210/0004 ,  A61F2250/0035 ,  A61F2250/0067 ,  A61L31/16 ,  A61L2300/216 ,  A61L2300/604 ,  A61L2300/606 ,  A61L2300/608 ,  A61L2300/63 ,  A61L2420/08

摘要： Provided herein is a device comprising: a. stent; b. a plurality of layers on said stent framework to form said device; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.

公开(公告)号：EP1937418B1

公开(公告)日：2018-07-25

申请号：EP06802188.0

申请日：2006-08-22

申请人： Quick-Med Technologies, Inc. ,  University of Florida Research Foundation, Inc.

发明人： TOREKI, William ,  LIESENFELD, Bernd ,  MOORE, David ,  LEANDER, Susan ,  BATICH, Christopher

IPC分类号： A01N33/12 ,  A61L15/46 ,  A61L2/232 ,  A61L2/18

CPC分类号： A01N33/12 ,  A01N37/12 ,  A61L2/18 ,  A61L2/232 ,  A61L15/46 ,  A61L2300/208 ,  A61L2300/216 ,  A61L2300/404 ,  A61L2300/80 ,  A01N25/10 ,  A01N25/24 ,  A01N25/34 ,  A01N2300/00

摘要： A method of bonding an antimicrobial cationic polyelectrolyte to the surface of a substrate is described, wherein the antimicrobial thus attached to the substrate provides the substrate with antimicrobial properties, and at least a portion of the bonded antimicrobial is substantially non-leachable during normal conditions of use and storage. A method of manufacturing an antimicrobial material is described which comprises exposure of the substrate to a solution of antimicrobial cationic polyelectrolyte, followed by drying the exposed substrate thoroughly to impart a non-leaching property to at least a portion of the antimicrobial cationic polyelectrolytes.

公开(公告)号：EP2271294B1

公开(公告)日：2018-03-28

申请号：EP09755571.8

申请日：2009-04-17

申请人： Micell Technologies, Inc.

发明人： MCCLAIN, James, B. ,  TAYLOR, Douglas

IPC分类号： A61L31/14 ,  A61L31/16 ,  A61L31/10

CPC分类号： A61L31/148 ,  A61F2/91 ,  A61F2210/0004 ,  A61F2250/0035 ,  A61F2250/0067 ,  A61L31/16 ,  A61L2300/216 ,  A61L2300/604 ,  A61L2300/606 ,  A61L2300/608 ,  A61L2300/63 ,  A61L2420/08

摘要： Provided herein is a device comprising: a. stent; b. a plurality of layers on said stent framework to form said device; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.

公开(公告)号：EP3295910A1

公开(公告)日：2018-03-21

申请号：EP17189897.6

申请日：2012-03-23

申请人： Unicharm Corporation

发明人： Komatsu, Shimpei ,  Noda, Yuki ,  Wada, Mitsuhiro ,  Hashino, Akira ,  Kinoshita, Hideyuki ,  Nakashita, Masashi ,  Wada, Ichiro

IPC分类号： A61F13/15 ,  A61F13/472 ,  A61F13/511 ,  A61K8/00 ,  A61L15/00

CPC分类号： A61F13/51113 ,  A61L15/20 ,  A61L15/42 ,  A61L15/44 ,  A61L15/48 ,  A61L2300/216

摘要： An object of the present disclosure is to provide an absorbent article without a sticky feel on the top sheet and with a smooth top sheet, even after highly viscous menstrual blood has been absorbed. The absorbent article of the present disclosure is as follows.
An absorbent article comprising a liquid-permeable top sheet, a liquid-impermeable back sheet and an absorbent body between the liquid-permeable top sheet and liquid-impermeable back sheet, wherein the liquid-permeable top sheet comprises a blood modifying agent with an IOB of 0.00-0.60, a melting point of no higher than 45°C, a water solubility of 0.00-0.05 g in 100 g of water at 25°C, and a weight-average molecular weight of no greater than 1,000.

公开(公告)号：EP2391632B1

公开(公告)日：2017-11-15

申请号：EP10736287.3

申请日：2010-01-26

申请人： Teleflex Medical Incorporated

发明人： GUPTA, Nisha ,  STEINKE, Elaine ,  PETERS, Erin ,  ROSENBLATT, Joel

IPC分类号： C07G11/00 ,  C07H15/00 ,  C07H17/00

CPC分类号： A61K45/06 ,  A61K31/047 ,  A61K33/14 ,  A61L29/14 ,  A61L29/16 ,  A61L2300/216 ,  A61L2300/404 ,  A61L2300/42 ,  A61K2300/00

公开(公告)号：EP2983727B1

公开(公告)日：2017-08-23

申请号：EP14726766.0

申请日：2014-04-09

申请人： Association For The Advancement Of Tissue Engineering And Cell Based Technologies & Therapies (A4TEC)

发明人： PEREIRA DA SILVA, Lucília ,  TEIXEIRA CERQUEIRA, Mariana ,  ROMERO AMANDI DE SOUSA, Rui Pedro ,  PINTO MARQUES, Alexandra Margarida ,  CORRELO DA SILVA, Vítor Manuel ,  GONÇALVES DOS REIS, Rui Luís

IPC分类号： A61L27/20 ,  A61L27/38 ,  A61L27/52 ,  C08J3/075 ,  C08L5/00

CPC分类号： A61L27/20 ,  A61L27/12 ,  A61L27/26 ,  A61L27/38 ,  A61L27/3804 ,  A61L27/3834 ,  A61L27/52 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/112 ,  A61L2300/216 ,  A61L2300/252 ,  A61L2300/414 ,  A61L2300/428 ,  A61L2400/18 ,  A61L2430/02 ,  C08J3/075 ,  C08J3/12 ,  C08J2305/00 ,  C08J2305/08 ,  C08K3/32 ,  C08K7/14 ,  C08L5/08 ,  C08L5/00

公开(公告)号：EP3132810A1

公开(公告)日：2017-02-22

申请号：EP15779986.7

申请日：2015-04-17

申请人： Seoul National University R&DB Foundation ,  Baiksan Co., Ltd.

发明人： CHOI, Tae Hyun ,  LEE, Yan ,  PARK, Ji Ung ,  HAM, Ji Yeon ,  KIM, Hee Jin ,  KIM, Suk Wha ,  MIN, Hye Jeong

IPC分类号： A61L27/34 ,  A61L27/32 ,  A61F2/12

CPC分类号： A61F2/12 ,  A61F2/0059 ,  A61L27/32 ,  A61L27/34 ,  A61L2300/216 ,  A61L2400/18 ,  A61L2430/04 ,  B05D1/02

摘要： The present invention relates to a coating composition for an in-vivo implantable prosthesis including a photoinitiator, a crosslinking agent, and a phosphorylcholine (PC) monomer having an acrylate group, a method of coating an in-vivo implantable prosthesis using the coating composition, and a cosmetic prosthesis coated with the crosslinked polyphosphorylcholine.
An in-vivo implantable prosthesis coated with crosslinked polyphosphorylcholine may be manufactured by a simple method of applying a coating composition including a photoinitiator, a crosslinking agent, and a phosphorylcholine (PC) monomer having an acrylate group according to the present invention, and then irradiating UV rays. The crosslinked polyphosphorylcholine coating may provide hydrophilicity for the surface and may also remarkably reduce adsorption of proteins and fibroblasts, which may cause side effects such as capsular contracture. Further, the coating has strong enough not to peel off even under stimulation, and therefore, it is maintained under vigorous activity after implantation, thereby being usefully applied to the manufacture of an in-vivo implantable prosthesis with reduced side effects, such as breast prosthesis for cosmetic surgery.

摘要翻译： 本发明涉及一种用于体内可植入假体的涂料组合物，其包括光引发剂，交联剂和具有丙烯酸酯基团的磷酸胆碱（PC）单体，使用该涂料组合物涂覆体内可植入假体的方法， 以及涂覆有交联的聚磷酰胆碱的化妆品假体。 涂布有交联聚磷酰胆碱的体内可植入假体可以通过施加包含光引发剂，交联剂和具有本发明的具有丙烯酸酯基团的磷酸胆碱（PC）单体的涂料组合物的简单方法制造，然后照射 紫外线。 交联的聚磷酰胆碱涂层可以为表面提供亲水性，并且还可以显着降低蛋白质和成纤维细胞的吸附，这可能引起副作用如荚膜挛缩。 此外，涂层即使在刺激下也足够坚固，不会剥离，因此在植入后保持活跃的活性，从而可用于制造具有减少的副作用的体内可植入假体，例如乳房假体 用于整容手术。

公开(公告)号：EP3030273A1

公开(公告)日：2016-06-15

申请号：EP14765985.8

申请日：2014-08-08

申请人： Locate Therapeutics Limited

发明人： QUIRK, Robin Andrew ,  COX, Helen Celia ,  SHAKESHEFF, Kevin Morris

IPC分类号： A61L27/50

CPC分类号： A61L27/18 ,  A61L27/50 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/216 ,  A61L2300/602 ,  A61L2400/06

摘要： An injectable agent delivery system comprising a composition that comprises: an agent for sustained delivery located within discrete particles; and an injectable scaffold material comprising discrete particles which are capable of interacting to form a scaffold, and uses thereof.

公开(公告)号：EP2815754B1

公开(公告)日：2016-06-08

申请号：EP14182618.0

申请日：2006-11-18

申请人： Glanbia Nutritionals (Ireland) Limited

发明人： Wolcott, Randall

IPC分类号： A61K35/20 ,  A61K33/38 ,  A61P17/02 ,  A61K31/7004 ,  A61K38/40 ,  A61P17/10 ,  A61K33/26 ,  A61K31/047 ,  A61L15/32 ,  A61L15/42 ,  A61L26/00 ,  A61K31/05 ,  A61K9/00 ,  A61K45/06 ,  A61K9/06 ,  A61K47/42 ,  A61L15/44 ,  A61K9/12 ,  A61K9/70

CPC分类号： A61K35/20 ,  A61K9/0014 ,  A61K9/06 ,  A61K9/122 ,  A61K9/7007 ,  A61K31/047 ,  A61K31/05 ,  A61K31/7004 ,  A61K33/26 ,  A61K38/40 ,  A61K45/06 ,  A61K47/26 ,  A61K47/42 ,  A61L15/32 ,  A61L15/425 ,  A61L15/44 ,  A61L26/0047 ,  A61L26/008 ,  A61L26/0085 ,  A61L2300/104 ,  A61L2300/216 ,  A61L2300/252 ,  A61L2300/45 ,  A61K2300/00