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    INHALER DEVICES AND BESPOKE PHARMACEUTICAL COMPOSITIONS
    1.
    发明公开
    INHALER DEVICES AND BESPOKE PHARMACEUTICAL COMPOSITIONS 审中-公开
    麻省理工学院药剂师ZUSAMMENSETZUNGEN

    公开(公告)号：EP2086523A2

    公开(公告)日：2009-08-12

    申请号：EP07824886.1

    申请日：2007-11-05

    Applicant: Vectura Limited

    Inventor： MORTON, David

    IPC: A61K9/72 ,  A61M15/00

    CPC classification number: A61K9/0075 ,  A61M11/001 ,  A61M15/0021 ,  A61M15/0026 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/0045 ,  A61M15/0051 ,  A61M15/006 ,  A61M15/0078 ,  A61M15/0081

    Abstract: The present invention relates to inhaler devices and bespoke pharmaceutical dry powder composition to be dispensed using such inhaler devices for pulmonary administration. In particular, the present invention relates to the provision of passive inhaler devices and dry powder compositions which are specifically formulated and prepared to be efficiently dispensed by such devices to reproducibly achieve a high delivered dose of the pharmaceutically active agent.

    Abstract translation: 本发明涉及使用这种用于肺部给药的吸入器装置来分配的吸入器装置和定制的药物干粉组合物。 特别地，本发明涉及提供被特别配制和制备的被动式吸入器装置和干粉组合物，以通过这些装置有效地分配以可再现地实现高递送剂量的药物活性剂。

    INHALER
    2.
    发明授权
    INHALER 有权

    公开(公告)号：EP2846860B1

    公开(公告)日：2018-04-25

    申请号：EP13723923.2

    申请日：2013-05-16

    Applicant: Vectura Delivery Devices Limited

    Inventor： MELINIOTIS, Andreas ,  SOLLY, Andrew ,  CLARKE, Roger ,  MCGUINNESS, Liam

    IPC: A61M15/08 ,  A61M11/00 ,  A61M15/00

    CPC classification number: A61M15/0058 ,  A61M11/003 ,  A61M15/0021 ,  A61M15/0025 ,  A61M15/0026 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/0045 ,  A61M15/0051 ,  A61M15/0056 ,  A61M15/006 ,  A61M15/0081 ,  A61M15/08 ,  A61M2202/064 ,  A61M2205/19

    Abstract: An inhaler comprising a housing defining a chamber to receive a strip having a plurality of blisters each containing a dose of medicament for inhalation by a user is disclosed. It comprises an inhaler comprising a housing to receive a strip having a plurality of blisters, each blister having a puncturable lid and containing a dose of medicament for inhalation by a user, a mouthpiece mounted to the housing and through which a dose of medicament is inhaled by a user, a blister piercing member mounted for rotation about a first axis and an actuating mechanism including an actuating lever mounted for rotation about a second axis to sequentially move each blister into alignment with the blister piercing member, wherein the actuating lever cooperates with the blister piercing member so that the blister piercing member pivots about said first axis in response to rotation of the actuating member from an initial position about the second axis to puncture the lid of an aligned blister so an airflow through the blister is generated to entrain the dose contained therein and carry it, via the mouthpiece, into the user's airway when a user inhales through the mouthpiece. The inhaler comprises an actuating lever load control member to control the force that must be applied to the actuating lever to cause it to rotate from its initial position such that a biasing force is applied to the actuating lever throughout all, or at least a substantial portion of, the stroke of the actuating lever.

    INHALER
    8.
    发明公开
    INHALER 有权
    气雾

    公开(公告)号：EP2846860A1

    公开(公告)日：2015-03-18

    申请号：EP13723923.2

    申请日：2013-05-16

    Applicant: Vectura Delivery Devices Limited

    Inventor： MELINIOTIS, Andreas ,  SOLLY, Andrew ,  CLARKE, Roger ,  MCGUINNESS, Liam

    IPC: A61M15/00

    CPC classification number: A61M15/0058 ,  A61M11/003 ,  A61M15/0021 ,  A61M15/0025 ,  A61M15/0026 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/0045 ,  A61M15/0051 ,  A61M15/0056 ,  A61M15/006 ,  A61M15/0081 ,  A61M15/08 ,  A61M2202/064 ,  A61M2205/19

    Abstract: An inhaler comprising a housing defining a chamber to receive a strip having a plurality of blisters each containing a dose of medicament for inhalation by a user is disclosed. It comprises an inhaler comprising a housing to receive a strip having a plurality of blisters, each blister having a puncturable lid and containing a dose of medicament for inhalation by a user, a mouthpiece mounted to the housing and through which a dose of medicament is inhaled by a user, a blister piercing member mounted for rotation about a first axis and an actuating mechanism including an actuating lever mounted for rotation about a second axis to sequentially move each blister into alignment with the blister piercing member, wherein the actuating lever co-operates with the blister piercing member so that the blister piercing member pivots about said first axis in response to rotation of the actuating member from an initial position about the second axis to puncture the lid of an aligned blister so an airflow through the blister is generated to en-train the dose contained therein and carry it, via the mouth-piece, into the users airway when a user inhales through the mouthpiece. The inhaler comprises an actuating lever load control member to control the force that must be applied to the actuating lever to cause it to rotate from its initial position such that a biasing force is applied to the actuating lever throughout all, or at least a substantial portion of, the stroke of the actuating lever.

    Abstract translation: 一种吸入器，其包括限定腔室的壳体，以容纳具有多个泡罩的条带，每个泡罩包含一定剂量的用户吸入的药物。 它包括吸入器，该吸入器包括用于容纳具有多个泡罩的条带的壳体，每个泡罩具有可刺破的盖子，并且包含一定剂量的用户吸入的药物，安装到壳体上的吸口，吸入一定剂量的药物 由使用者安装的用于围绕第一轴线旋转的泡罩刺穿构件和包括安装成围绕第二轴线旋转的致动杆的致动机构，以顺序地移动每个泡罩与泡罩穿孔构件对准，其中所述致动杆协作 与泡罩刺穿构件一起使得泡罩刺穿构件响应于致动构件从关于第二轴线的初始位置的旋转而围绕所述第一轴线枢转，以刺穿对准的泡罩的盖子，从而产生通过泡罩的气流到en - 当使用者通过接口管吸入时，训练其中所含的剂量并将其通过口件运送到使用者的气道中。 吸入器包括致动杆负载控制构件，用于控制必须施加到致动杆的力以使其从其初始位置旋转，使得偏压力在整个或至少大部分中被施加到致动杆 的驱动杆的行程。

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