摘要:
An apparatus comprising a housing, a reservoir comprising a fluid and having an openable end, an applicator having a first major surface comprising a microneedle array, a pathway communicable between the openable end and the microneedle array, the housing supporting independently the applicator and the reservoir, a first stored energy device actuatable for applying force to the applicator to accelerate the applicator in a direction generally normal to the first major surface, and a second stored energy device actuatable for automatically opening the openable end, such that the openable end and the pathway are in fluid communication, and wherein the actuated second stored energy device forces the fluid through the openable end, the pathway, and the microneedle array, and wherein the first and second stored energy devices are comprised of at least one stored energy device from a group consisting of spring devices, gaseous propellants, chemicals, electrical devices, and combinations thereof.
摘要:
The invention relates to an actuating device for administering a bolus, comprising an actuating element (12), which can be slid from an upper position to a lower position in order to actuate a closing mechanism, which opens a segment (18) of a hose in the lower position of the actuating element (12) and closes the hose segment (18) in the upper position of the actuating element (12), wherein the hose segment (18) can be connected to a fluid source by means of an inflow line (20) and to a patient by means of an outflow line (22), comprising a movable element (14), which can be slid from an upper position to a lower position independently of the actuating element (12), comprising a blocking means (15), which locks the movable element (14) in the upper position and which can be released by the actuating element (12) by sliding the actuating element in the direction of the lower position, comprising an elastic element (16), which pushes the actuating element (12) and the movable element (14) apart, comprising a first actuation blocking means (24), which locks the actuating element (12) in the lower position of the actuating element and can be released by the movable element (14) in the lower position of the movable element, comprising a bolus reservoir (26) for holding a bolus amount of a fluid, wherein the volume of the bolus reservoir (26) can be reduced by sliding the movable element (14) in the direction of the lower position of the movable element, and comprising a second actuation blocking means (28), which locks the actuating element (12) in the upper position of the actuating element and can be released by the movable element (14) in the upper position of the movable element.
摘要:
Systems and methods for infusion of fluids using stored potential energy and a variable flow resistor (60) . In one aspect of the present disclosure, there is provided an infusion device (10) that includes a plunger (24) situated within a vessel (11) so as to define a chamber (26) within which a volume of fluid (40) can be accommodated between a downstream surface of the plunger and the vessel. The infusion device further includes an outflow path (13) through which the fluid in the chamber can be dispensed upon displacement of the plunger by a force acting thereon. A variable flow resistor is situated within the outflow path and is configured to allow a substantially constant fluid flow rate from the vessel to be maintained as the force acting on the plunger decreases.
摘要:
An assembly is provided which includes an infusion device coupled to a standard medication syringe. The medication syringe may be coupled to a stopcock valve having multiple ports and to which syringes, vial adapters, infusion tubing, and multiple other items may be coupled. The infusion device includes a source of power based on a resistance force such as vacuum, spring or gas power. The infusion device converts the resistance based force to usable work in the form of a force applicator. The force applicator includes a driver section on one section of a reciprocating arm and an attachment to the power source on another section of the arm. The driver is pulled outward (excursion) to increase the size of the chamber, creating a force that tends to return the driver back inward, causing incursion. The driver can be attached removably to the syringe plunger to induce the infusion process.
摘要:
A medicament delivery device comprising a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further comprising a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber. The first stopper is connected to the second stopper by a tensile member such that axially forwardly movement of the first stopper causes axially forwardly movement of the second stopper due to tensioning of the tensile member. The first stopper is driveable in an axially forwardly direction, the first chamber is configured to contain medicament for delivery through the delivery outlet as the first stopper moves axially forwards, the third chamber contains a viscous fluid that enters the venting chamber via the vent outlet as the second stopper moves axially forwards, and the fourth chamber has a pressure that is substantially equal to or greater than the pressure of the venting chamber. As the first stopper is driven axially forwardly, the tensile member is tensioned and causes the second stopper to move axially forwardly and the venting of viscous fluid into the venting chamber via the vent outlet retards the axially forward movement of the second stopper and the first stopper.