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19 条记录 (耗时 0.009 秒)

    STIRRING DEVICE AND METHOD
    1.
    发明公开
    STIRRING DEVICE AND METHOD 审中-公开
    UMRÜHRRORRICHTUNG全面展开

    公开(公告)号：EP2939734A1

    公开(公告)日：2015-11-04

    申请号：EP12891151.8

    申请日：2012-12-25

    申请人： M Technique Co., Ltd.

    发明人： ENOMURA Masakazu

    IPC分类号： B01F7/16

    CPC分类号： B01F5/0661 ,  B01F3/0807 ,  B01F7/0085 ,  B01F7/1635 ,  B01F7/166

    摘要： The present invention has an object to provide a stirring processing apparatus and a processing method to realize excellent processing of a fluid regardless of the properties of the fluid. The stirring processing apparatus is provided with the stirring blade 22 and the stirring chamber 18 provided with the screen 23, wherein the apparatus performs, under a state in which the stirring chamber 18 is disposed in a fluid to be processed, a process of applying a shear force to the fluid by a relative rotation between the screen 23 and the stirring blade 22. The stirring chamber 18 is provided with the suction opening 24 to suck the fluid from outside to inside and the ejecting opening 25 to eject the fluid from inside to outside; these openings being disposed above and below. The suppressing body 31 to control a flow of the fluid is disposed between the suction opening 24 and the ejecting opening 25. The suppressing body 31 is, for example, in the form of a cylinder, and is interposed between the suction flow 26 and the ejecting flow 27, thereby suppressing interference between the two flows.

    摘要翻译： 本发明的目的是提供一种搅拌处理装置和处理方法，其与流体的性质无关地实现流体的优异的加工。 搅拌处理装置设置有搅拌叶片22和设置有筛网23的搅拌室18，其中该装置在将搅拌室18设置在待处理流体中的状态下进行施加 通过筛网23和搅拌叶片22之间的相对旋转对流体施加剪切力。搅拌室18设置有吸入口24以从外部到内部吸入流体，并且喷射口25将流体从内部喷射到 外; 这些开口设置在上下。 用于控制流体流动的抑制体31设置在吸入口24和排出口25之间。抑制体31例如为气缸形式，并且设置在吸入流26和排出口25之间。 喷射流27，从而抑制两个流之间的干扰。

    SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF
    4.
    发明公开
    SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF 有权
    FESTE DISPERSIONEN AUSUNLÖSLICHENARZNEIMITTELN UND HERSTELLUNGSVERFAHRENDAFÜR

    公开(公告)号：EP2917188A1

    公开(公告)日：2015-09-16

    申请号：EP13854140.4

    申请日：2013-11-07

    申请人： SK Biopharmaceuticals Co., LTD

    发明人： BAEK, Myoung Ki ,  PEGAN, Augustin

    IPC分类号： C07D261/08 ,  A61K31/42 ,  A61P25/00

    CPC分类号： A61K31/42 ,  A61K9/0053 ,  A61K9/10 ,  A61K9/146 ,  A61K9/2027 ,  A61K9/2031 ,  A61K47/32 ,  B01F3/186 ,  B01F3/2276 ,  B01F7/0085 ,  B01F15/06 ,  B01F2015/062 ,  B01F2215/0032 ,  C07D261/08

    摘要： The present invention relates to a solid dispersion characterized in that it comprises carbamic acid 3-(4-benzyloxy-phenyl)-isoxazol-5-ylmethyl ester as an active ingredient and a water-soluble polymer having a glass transition temperature lower than the melting point of the active ingredient as a carrier, and it is prepared via melt extrusion. The solid dispersion of the present invention remarkably increases the solubility and dissolution rate of the active ingredient which is an insoluble drug to efficiently improve the bioavailability when it is orally administered.

    摘要翻译： 本发明涉及一种固体分散体，其特征在于它包括氨基甲酸3-（4-苄氧基 - 苯基） - 异恶唑-5-基甲酯作为活性成分和玻璃化转变温度低于熔点的水溶性聚合物 作为载体的活性成分，通过熔融挤出制备。 本发明的固体分散体显着增加作为不溶性药物的活性成分的溶解度和溶解速度，以有效地提高口服给药时的生物利用度。

    STIRRING DEVICE AND METHOD
    6.
    发明公开
    STIRRING DEVICE AND METHOD 审中-公开
    搅拌和程序

    公开(公告)号：EP2939734A4

    公开(公告)日：2016-08-24

    申请号：EP12891151

    申请日：2012-12-25

    申请人： M TECH CO LTD

    发明人： ENOMURA MASAKAZU

    IPC分类号： B01F7/16 ,  B01F3/08 ,  B01F5/06 ,  B01F7/00

    CPC分类号： B01F5/0661 ,  B01F3/0807 ,  B01F7/0085 ,  B01F7/1635 ,  B01F7/166

    摘要： The present invention has an object to provide a stirring processing apparatus and a processing method to realize excellent processing of a fluid regardless of the properties of the fluid. The stirring processing apparatus is provided with the stirring blade 22 and the stirring chamber 18 provided with the screen 23, wherein the apparatus performs, under a state in which the stirring chamber 18 is disposed in a fluid to be processed, a process of applying a shear force to the fluid by a relative rotation between the screen 23 and the stirring blade 22. The stirring chamber 18 is provided with the suction opening 24 to suck the fluid from outside to inside and the ejecting opening 25 to eject the fluid from inside to outside; these openings being disposed above and below. The suppressing body 31 to control a flow of the fluid is disposed between the suction opening 24 and the ejecting opening 25. The suppressing body 31 is, for example, in the form of a cylinder, and is interposed between the suction flow 26 and the ejecting flow 27, thereby suppressing interference between the two flows.

    Rotating stirring device with substantially narrow distribution of energy dissipation rate
    8.
    发明公开
    Rotating stirring device with substantially narrow distribution of energy dissipation rate 审中-公开
    旋转搅拌装置的能量耗散率分布范围很窄

    公开(公告)号：EP1504809A1

    公开(公告)日：2005-02-09

    申请号：EP03019330.4

    申请日：2003-08-27

    申请人： ETH Zürich

    发明人： Morbidelli, Massimo ,  Soos, Miroslav ,  Wu, Hua

    IPC分类号： B01F7/28 ,  B01F7/00 ,  B01F15/06 ,  B01J19/18 ,  B01J10/02

    CPC分类号： B01F7/008 ,  B01F7/0085 ,  B01F7/28 ,  B01F15/00909 ,  B01F15/065 ,  B01F15/068 ,  B01F2215/0431 ,  B01F2215/0463 ,  B01F2215/0481 ,  B01J10/02 ,  B01J19/1887 ,  B01J2219/00094

    摘要： A rotating stirring device for generating substantially narrow distribution of energy dissipation rate and avoiding presence of Taylor vortices is disclosed. The device comprises an outer cylinder (1) with cross-section of circular shape and an inner cylinder (2) with cross-section of equilateral or inequilateral polygon shape of curved cusps. The inner cylinder is concentrically placed within the outer cylinder and rotates. Such device is particularly advantageous as a reactor or mixer for processes where chemical and physical properties are sensitive to the variations in the shear rate and for processes that involve fragile components. The device can be also used to replace Taylor Couette device for the purposes of improving mass transfer and of avoiding separation of components in the gap in the case of presence of differences in density among components.

    摘要翻译： 公开了一种旋转搅拌装置，用于产生能量耗散率的基本上较窄的分布并避免泰勒旋涡的存在。 该装置包括具有圆形横截面的外圆柱体（1）和具有弯曲的尖角的等边或不等边多边形形状的横截面的内圆柱体（2）。 内筒同心地放置在外筒内并旋转。 这样的装置对于化学和物理性质对剪切速率的变化敏感的工艺以及涉及易碎组分的工艺的反应器或混合器特别有利。 该装置也可以用来代替Taylor Couette装置，以便在组件间密度不同的情况下，改善传质并避免间隙中组分的分离。

    WERKZEUG ZUR RHEOLOGIEMESSUNG
    10.
    发明公开
    WERKZEUG ZUR RHEOLOGIEMESSUNG 审中-公开
    工具流变测量

    公开(公告)号：EP3182093A1

    公开(公告)日：2017-06-21

    申请号：EP16201110

    申请日：2016-11-29

    申请人： KNIELE BAUMASCHINEN GMBH ,  UNIVERSITÄT STUTTGART

    发明人： KNIELE HARALD ,  KNIELE ALEXANDER ,  BAUMERT CHRISTIAN ,  GARRECHT HARALD

    IPC分类号： G01N11/14 ,  B01F7/00

    CPC分类号： G01N11/14 ,  B01F7/00416 ,  B01F7/007 ,  B01F7/0085

    摘要： Die vorliegende Erfindung bezieht sich auf ein Werkzeug (1), welches eine Rheologiemessung unterstuützt. Das Werkzeug (1) weist ein im Wesentlichen innen hohles zylinderförmiges Element (2) auf, in dessen Hohlraum ein inneres Werkzeugs zur Rheologiemessung (7) angeordnet werden kann. Das Werkzeug (1) weist Mischelemente (2) sowie Aussparungen in der Mantelfläche des zylinderförmigen Bauteils (2) auf und ist durch einen Antrieb (7) bewegbar bzw. rotierbar. Somit kann das zu vermessende Medium vor der Rheologiemessung durchmischt werden, so dass die Eigenschaften einer homogenen Mischung bestimmt werden können.