公开(公告)号：EP0499613A1

公开(公告)日：1992-08-26

申请号：EP90916116.0

申请日：1990-10-24

申请人： NOVO NORDISK A/S

发明人： REX, J rgen

IPC分类号： A61J7 ,  A61M13 ,  A61M15 ,  B05B11

CPC分类号： B05B11/064 ,  A61M11/02 ,  A61M15/0025 ,  A61M15/0026 ,  A61M15/0028 ,  A61M15/0036 ,  A61M15/0045 ,  A61M15/0048 ,  A61M15/0073 ,  A61M2202/064 ,  A61M2205/073 ,  A61M2205/6081 ,  B05B11/062

摘要： L'invention se rapporte à un distributeur manuel pour le dosage de substances pulvérulentes, qui comprend un cylindre compresseur (2) contenant un piston axialement mobile (3). On génère une pression supérieure à la pression atmosphérique en déplaçant le piston vers l'intérieur dans le cylindre et le relâchement de cette pression se fait à travers une chambre (41) située dans un magasin (40), lequel comprend un certain nombre de chambres (41) contenant la substance pulvérulente. Les extrémités des chambres (41) sont couvertes par des membranes pénétrables et les chambres (41) peuvent être déplacées de façon à s'aligner successivement sur un organe de pénétration (30) et un conduit de sortie (46). Lorsque le piston (3) se trouve dans sa position la plus intérieure, l'organe de pénétration (30) et l'extrémité d'entrée du conduit de sortie (46) percent les membranes respectives situées aux extrémités de la chambre (41) et la pression subatmosphérique est relâchée à travers la chambre (41), dont le contenu est alors distribué à travers le conduit de sortie (46). Le magasin (40) est annulaire et comprend un certain nombre de chambres tubulaires (41) placées à équidistance entre elles et à une certaine distance parallèlement par rapport à l'axe du magasin (40). A chaque course entière du piston (3), le magasin (40) est mis en rotation de façon à placer une nouvelle chambre (41) en alignement par rapport à l'organe de pénétration (30) et au conduit de sortie (46).

公开(公告)号：EP1028815A4

公开(公告)日：2007-10-17

申请号：EP98958577

申请日：1998-11-13

申请人： LOVELACE RESPIRATORY RES INST

发明人： GERDE PER MAGNUS

IPC分类号： A61M15/00 ,  B05B7/00 ,  B05B7/14 ,  B05B11/06 ,  B05B7/26

CPC分类号： B05B11/064 ,  A61M15/00 ,  A61M15/003 ,  A61M15/0045 ,  A61M15/0065 ,  A61M2202/064 ,  A61M2205/07 ,  B05B7/0012 ,  B05B7/1486 ,  B05B11/062 ,  B05B11/065

摘要： An apparatus (10) and method for aerosolizing and dispensing powders utilizing the forces of pressurizing and depressurizing gas loaded into powder agglomerates. The major components of the apparatus (10) include pressure chamber (14), powder chamber (12), pressure conduit (18), ejecting conduit (20), nozzle (22), and valve (16). Methods include administering peptides, genes, vitamines, and polymers into the peripheral lung. The invention is further of powder supply apparatus (10) and method for single dose and repetitive applications.

公开(公告)号：EP1575845A1

公开(公告)日：2005-09-21

申请号：EP03778407.1

申请日：2003-10-20

申请人： Valois SAS

发明人： MILIAN, Alex

IPC分类号： B65D83/00 ,  B05B11/04 ,  A61M15/00 ,  A45D40/00 ,  B65D81/32

CPC分类号： B05B11/064 ,  A45D37/00 ,  A45D40/0087 ,  A61M11/02 ,  A61M15/0003 ,  A61M15/0028 ,  A61M2202/064 ,  A61M2205/075 ,  B05B11/0037 ,  B05B11/0081 ,  B05B11/06 ,  B05B11/068 ,  B65D75/30 ,  B65D81/3294 ,  B65D83/0055

摘要： The invention concerns a fluid product dispenser characterized in that it comprises: a gas reservoir (12) defining an actuating wall (120) to cause the reservoir volume to vary thereby driving the gas out of said reservoir; at least one fluid product reservoir (13) defining an actuating wall (130) to cause the reservoir volume to vary thereby driving the fluid product out of the reservoir; at least an outlet (141) common to the gas reservoir (12) and to a fluid product reservoir (13); a gas supply conduit (15) connecting the gas reservoir (12) to the common outlet (141); and at least a fluid product supply channel (16) connecting the fluid product reservoir (13) to the common outlet (141).

摘要翻译： 流体产品分配器技术领域本发明涉及一种流体产品分配器，其特征在于包括：气体储存器（12），其限定致动壁（120）以使储存体积改变，从而将气体驱出所述储存器; 至少一个流体产品贮存器（13），其限定致动壁（130）以引起贮存器体积改变从而将流体产品驱出所述贮存器; 至少一个气体贮存器（12）和流体产品贮存器（13）共用的出口（141）; 将气体储存器（12）连接到公共出口（141）的气体供应管道（15）; 以及至少一个将流体产品储存器（13）连接到公共出口（141）的流体产品供应通道（16）。

公开(公告)号：EP0499613B1

公开(公告)日：1994-08-10

申请号：EP90916116.8

申请日：1990-10-24

申请人： NOVO NORDISK A/S

发明人： REX, Jorgen

IPC分类号： A61M15/00

CPC分类号： B05B11/064 ,  A61M11/02 ,  A61M15/0025 ,  A61M15/0026 ,  A61M15/0028 ,  A61M15/0036 ,  A61M15/0045 ,  A61M15/0048 ,  A61M15/0073 ,  A61M2202/064 ,  A61M2205/073 ,  A61M2205/6081 ,  B05B11/062

摘要： A manually operated dispenser for dispensing a predetermined amount of powdered substance comprises a pressure cylinder (2) with an axially displaceable piston (3). A superatmospheric pressure is generated by displacing the piston inwardly in the cylinder and is releaved through a chamber (41) in a magazine (40) comprising a number of chambers (41) containing powdered substance. The ends of the chambers (41) are covered by penetrable membranes, and the chambers (41) may be moved to successively being in alignment with a penetrator (30) and an outlet pipe (46). When the piston (3) is in its innermost position the penetrator (30) and the inlet end of the outlet pipe (46) are forced through the respective membranes at the ends of the chamber (41), and the subatmospheric pressure is releaved through the chamber (41) to dispense its content through the outlet pipe (46). The magazine (40) is annular and comprises a number of tubular chambers (41) placed equidistantly at some distance from and parallel with the axis of the magazine (40). At each full displacement of the piston (3) the magazine (40) is rotated to bring a new chamber (41) in alignment with the penetrator (30) and the outlet pipe (46).

公开(公告)号：EP2833950A1

公开(公告)日：2015-02-11

申请号：EP13716254.1

申请日：2013-04-05

申请人： RPC Formatec GmbH

发明人： KRIEGER, Johannes

IPC分类号： A61M11/06 ,  B05B7/00 ,  B05B7/14 ,  B05B11/06 ,  A61M15/00

CPC分类号： B05B11/061 ,  A61M11/007 ,  A61M11/06 ,  A61M15/0015 ,  A61M15/002 ,  A61M15/0045 ,  A61M2205/073 ,  B05B7/0012 ,  B05B7/1486 ,  B05B11/064 ,  B05B11/067

摘要： The invention relates first of all to a dispenser (1) for discharging an in particular granular or powdery substance (2) by blow-out, with a blow-out duct, and with a suction line (5) opening into the blow-out duct (4) for sucking the substance (2) into the blow-out duct (4). In order to provide a dispenser of this kind that permits such a use in a reliable way and by simple means, particularly in manual operation, it is proposed that a positive air pressure can be built up in a duct section (7) arranged upstream of the blow-out duct (4) and closed in the direction of the blow-out duct (4) by a valve (6) opening in a pressure-dependent manner, for pressure-controlled formation of a blow-out stream in the blow-out duct (4). The invention also relates to a method for emptying a substance reservoir having a freeze-dried substance. In order to provide a method of this kind that permits such a use in a reliable way and by simple means, it is proposed that the substance is sucked out of the substance reservoir, by means of a suction air stream opening into a blowing stream, and discharged. The invention further relates to a use of a sucking/blowing dispenser for emptying a substance reservoir having a freeze-dried substance.

公开(公告)号：EP0652784B1

公开(公告)日：1999-03-17

申请号：EP93900033.7

申请日：1992-12-11

申请人： BOEHRINGER INGELHEIM INTERNATIONAL GmbH ,  Boehringer Ingelheim Pharma KG

发明人： ZIERENBERG, Bernd ,  HOCHRAINER, Dieter

IPC分类号： A61M15/00 ,  B05B11/06 ,  B05B11/00

CPC分类号： B05B11/3091 ,  A61M15/0045 ,  A61M15/0048 ,  A61M2205/073 ,  B05B11/062 ,  B05B11/064

摘要： The invention concerns an inhaler for medication in powder form, the inhaler having flat carriers (1) with regular surface microfeatures (3) between which the inhalation powder is incorporated.

公开(公告)号：EP0530625B1

公开(公告)日：1996-09-25

申请号：EP92114370.7

申请日：1992-08-22

申请人： Ing. Erich Pfeiffer GmbH

发明人： Güntert, Bernhard ,  Wolter, Michael ,  Ritsche, Stefan ,  Jäger-Waldau, Reinhold ,  Fuchs, Karl-Heinz

IPC分类号： B05B7/14 ,  A61M13/00

CPC分类号： B05B11/064 ,  A61M13/00 ,  A61M15/0028 ,  A61M15/0035 ,  A61M15/0045 ,  A61M15/0065 ,  A61M2202/064 ,  A61M2205/073 ,  B05B11/062

公开(公告)号：EP0957962B1

公开(公告)日：2004-03-31

申请号：EP98905326.9

申请日：1998-01-21

申请人： Ing. Erich Pfeiffer GmbH

发明人： KÄFER, Stefan

IPC分类号： A61M15/00

CPC分类号： B05B11/064 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/0045 ,  A61M15/0048 ,  A61M2202/064 ,  B05B11/062

摘要： In order to dispense a medium, such as a powder, a foil seal (16) of a storage chamber (24) is pierced by a tool (40) in a first axial movement, whereupon the medium is suctioned out of the chamber (24) via an outlet (9) by feeding a conveyor flow through channels (55). After carrying out a return stroke and after rotating the tool (40) in relation to the storage device (6), an additional chamber (24) can be emptied in similar fashion. This enables, for instance, a pharmaceutical active substance to be administered in two individual doses as required for nasal treatment.

公开(公告)号：EP0957962A1

公开(公告)日：1999-11-24

申请号：EP98905326.0

申请日：1998-01-21

申请人： Ing. Erich Pfeiffer GmbH

发明人： KÄFER, Stefan

IPC分类号： A61M15 ,  B05B11

CPC分类号： B05B11/064 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/0045 ,  A61M15/0048 ,  A61M2202/064 ,  B05B11/062

摘要： In order to dispense a medium, such as a powder, a foil seal (16) of a storage chamber (24) is pierced by a tool (40) in a first axial movement, whereupon the medium is suctioned out of the chamber (24) via an outlet (9) by feeding a conveyor flow through channels (55). After carrying out a return stroke and after rotating the tool (40) in relation to the storage device (6), an additional chamber (24) can be emptied in similar fashion. This enables, for instance, a pharmaceutical active substance to be administered in two individual doses as required for nasal treatment.

公开(公告)号：EP0652784A1

公开(公告)日：1995-05-17

申请号：EP93900033.0

申请日：1992-12-11

申请人： BOEHRINGER INGELHEIM INTERNATIONAL GmbH

发明人： ZIERENBERG, Bernd ,  HOCHRAINER, Dieter

IPC分类号： A61M13 ,  A61M15 ,  B05B11

CPC分类号： B05B11/3091 ,  A61M15/0045 ,  A61M15/0048 ,  A61M2205/073 ,  B05B11/062 ,  B05B11/064

摘要： The invention concerns an inhaler for medication in powder form, the inhaler having flat carriers (1) with regular surface microfeatures (3) between which the inhalation powder is incorporated.