-
1.发明公开Heterotricyclic compounds, processes for their production and pharmaceutical compositions containing them 失效三环杂化合物，它们的制备方法和含有它们的药物组合物。
公开(公告)号：EP0006283A1
公开(公告)日：1980-01-09
申请号：EP79300617.2
申请日：1979-04-12
IPC分类号： C07D307/93 , C07D311/94 , C07D333/50 , C07D333/78 , C07D335/04 , A61K31/34 , A61K31/35 , A61K31/38
CPC分类号： C07D333/50 , C07D307/93 , C07D311/02 , C07D333/78 , C07D335/04 , C07D337/00
摘要： A compound of the formula:
wherein A, is a single bond or a C 1 -C 5 alkylene group bonding at the 2- or 3-position, A 2 is a C 1 -C 4 alkylene group, A 3 is a single bond or a C 1 -C 3 alkylene group, X-Y is -O-CH 2 - -O-CO- or -SO n -CH 2 - and B is a carboxy group, a C 2 -C 5 alkoxycarbonyl group, a cyano group, a hydroxy group, a C 2 -C 5 acyloxy group, a halogen group, a carbamoyl group of the formula:
or an amino group of the formula:
The compounds of the invention are useful as antiviral agents against, for example, influenza virus and herpes simplex virus.摘要翻译： 式的化合物：A1 worin
是一个单键或在2-，2'-或3位上的C1-C5，亚烷基键合，A2是C1-C3亚烷基基团，A3是C1 C4亚烷基基团，X为-O-或-SOn-和B为羧基，C2-C5烷氧羰基，氰基至氨基酸式基团： 或下式的氨基甲酰基：< IMAGE>所有这是因为与没有副作用抗病毒剂是有用的。 -
公开(公告)号：EP2301927B1
公开(公告)日：2016-01-27
申请号：EP10175215.2
申请日：2006-03-30
IPC分类号： C07D313/00 , C11B9/00
CPC分类号： C07D313/00 , C07C45/69 , C07C49/427 , C07D337/00 , C11B9/0038 , C11B9/0049 , C11B9/0084 , C11B9/0092
-
公开(公告)号：EP2301927A1
公开(公告)日：2011-03-30
申请号：EP10175215.2
申请日：2006-03-30
IPC分类号： C07D313/00 , C11B9/00
CPC分类号： C07D313/00 , C07C45/69 , C07C49/427 , C07D337/00 , C11B9/0038 , C11B9/0049 , C11B9/0084 , C11B9/0092
摘要： The present invention is directed to a cyclopropanated macrocyclic lactone compound of the formula
and the use of this compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products.摘要翻译： 本发明涉及下式的环丙烷化大环内酯化合物，以及该化合物在制备香料中的用途，以及香料，古龙水和个人护理产品中的香料。
-
公开(公告)号：EP1712538B1
公开(公告)日：2011-07-27
申请号：EP06251763.6
申请日：2006-03-30
IPC分类号： C07C49/427 , C07D313/00 , C11B9/00 , A61K8/35 , A61K8/49 , A61Q13/00
CPC分类号： C07D313/00 , C07C45/69 , C07C49/427 , C07D337/00 , C11B9/0038 , C11B9/0049 , C11B9/0084 , C11B9/0092
-
公开(公告)号：EP1712538A1
公开(公告)日：2006-10-18
申请号：EP06251763.6
申请日：2006-03-30
IPC分类号： C07C49/427 , C07D313/00 , C11B9/00 , A61K8/35 , A61K8/49 , A61Q13/00
CPC分类号： C07D313/00 , C07C45/69 , C07C49/427 , C07D337/00 , C11B9/0038 , C11B9/0049 , C11B9/0084 , C11B9/0092
摘要： The present invention is directed to novel cyclopropanated macrocyclic ketone and lactone compounds of the general formula
wherein X is an atom or a functional group selected from the group consisting of O, N, S, CH, or CH 2 ;
wherein Y is a straight or branched hydrocarbon moiety consisting of 1 to 20 carbon atoms;
wherein W is a straight or branched hydrocarbon moiety of consisting of 1 to 20 carbon atoms; and
wherein O is an oxygen atom;
and the use of these novel compounds in creating fragrances, and scents in items such as perfumes, colognes and personal care products.摘要翻译： 本发明涉及新的环丙烷化大环酮和通式的内酯化合物，其中X是选自O，N，S，CH或CH 2的原子或官能团; 其中Y是由1至20个碳原子组成的直链或支链烃部分; 其中W是由1至20个碳原子组成的直链或支链烃部分; 并且其中O是氧原子; 以及这些新型化合物在制造香料中的用途以及香水，古龙水和个人护理产品中的香料。
-
公开(公告)号：EP0652749A4
公开(公告)日：1997-04-09
申请号：EP93910950
申请日：1993-04-30
申请人： ARCH DEV CORP
发明人： LIAO SHUTSUNG , LIANG TEHMING
IPC分类号： G01N33/74 , A61K8/00 , A61K8/14 , A61K8/30 , A61K8/35 , A61K8/36 , A61K8/368 , A61K8/37 , A61K8/49 , A61K8/67 , A61K9/127 , A61K31/19 , A61K31/20 , A61K31/23 , A61K31/353 , A61K31/38 , A61K31/40 , A61K31/557 , A61K31/565 , A61K45/06 , A61K47/42 , A61P3/06 , A61P13/02 , A61P15/00 , A61P17/00 , A61P35/00 , A61Q5/00 , A61Q7/00 , A61Q19/00 , C07C53/00 , C07C53/21 , C07C57/03 , C07C57/26 , C07C57/30 , C07C57/46 , C07C57/52 , C07C57/56 , C07C61/16 , C07C61/40 , C07C69/63 , C07C69/65 , C07C69/675 , C07C69/716 , C07C69/738 , C07C69/88 , C07D209/48 , C07D225/02 , C07D313/00 , C07D317/64 , C07D331/00 , C07D337/00 , C12N9/99 , A61K31/275 , A61K31/33 , A61K31/335 , A61K31/695
CPC分类号： C07D337/00 , A61K8/361 , A61K8/37 , A61K8/4906 , A61K8/4973 , A61K8/67 , A61K31/20 , A61K31/23 , A61K31/353 , A61K31/565 , A61K45/06 , A61K2800/782 , A61Q5/00 , A61Q19/00 , C07C53/21 , C07C57/52 , C07C57/56 , C07C61/16 , C07C61/40 , C07C69/63 , C07C69/65 , C07C69/675 , C07C69/716 , C07C69/738 , C07C69/88 , C07D209/48 , C07D225/02 , C07D313/00 , A61K2300/00
摘要： Disclosed are a novel class of anti-androgenic compounds including saturated and unsaturated fatty acids, their derivatives, and synthetic analogs, according to the following formula: CH3-(CH2)a-(CR1R2CH=CH)b-(CH2)c-COOH, wherein R1 and R2 are each either hydrogen or a halogen; wherein a and c are integers from 0-9; wherein b is an integer from 1-6, provided that 12
-
公开(公告)号：EP0652749A1
公开(公告)日：1995-05-17
申请号：EP93910950.0
申请日：1993-04-30
发明人： LIAO, Shutsung , LIANG, Tehming
IPC分类号： G01N33 , A61K8 , A61K9 , A61K31 , A61K45 , A61K47 , A61P3 , A61P13 , A61P15 , A61P17 , A61P35 , A61Q5 , A61Q7 , A61Q19 , C07C53 , C07C57 , C07C61 , C07C69 , C07D209 , C07D225 , C07D313 , C07D317 , C07D331 , C07D337 , C12N9
CPC分类号： C07D337/00 , A61K8/361 , A61K8/37 , A61K8/4906 , A61K8/4973 , A61K8/67 , A61K31/20 , A61K31/23 , A61K31/353 , A61K31/565 , A61K45/06 , A61K2800/782 , A61Q5/00 , A61Q19/00 , C07C53/21 , C07C57/52 , C07C57/56 , C07C61/16 , C07C61/40 , C07C69/63 , C07C69/65 , C07C69/675 , C07C69/716 , C07C69/738 , C07C69/88 , C07D209/48 , C07D225/02 , C07D313/00 , A61K2300/00
摘要： Disclosed is a novel class of antiandrogenic compounds including saturated and unsaturated fatty acids, their derivatives, and synthetic analogs, their method of synthesis, and their use in treating disorders associated with androgenic activities. Also disclosed is the use of known compounds not previously known for their antiandrogenic activity in treating disorders related to androgenic activities.
-
8.发明授权
公开(公告)号：EP0006283B1
公开(公告)日：1983-01-26
申请号：EP79300617.2
申请日：1979-04-12
IPC分类号： C07D307/93 , C07D311/94 , C07D333/50 , C07D333/78 , C07D335/04 , A61K31/34 , A61K31/35 , A61K31/38
CPC分类号： C07D333/50 , C07D307/93 , C07D311/02 , C07D333/78 , C07D335/04 , C07D337/00
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.008 秒)
