Semiconductor nanocrystal probes for biological applications
    1.
    发明授权
    Semiconductor nanocrystal probes for biological applications 有权
    Halbleiternanok结晶生物制剂Anwendungen

    公开(公告)号:EP2180321B1

    公开(公告)日:2014-10-08

    申请号:EP09014899.0

    申请日:2000-02-28

    摘要: A semiconductor nanocrystal compound capable of linking to one or more affinity molecules comprising (1) one or more semiconductor nanocrystals capable of, in response to exposure to a first energy, providing a second energy, and (2) one or more linking agents, having a first portion linked to the one or more semiconductor nanocrystals and a second portion capable of linking to one or more affinity molecules. One or more of semiconductor nanocrystal compounds linked to one or more affinity molecules to form a semiconductor nanocrystal probe capable of bonding with one or more detectable substances in a material being analyzed, and are capable of, in response to exposure to a first energy, providing a second energy. The probe is capable of emitting electromagnetic radiation in a narrow wavelength band and/or absorbing, scattering, or diffracting energy when excited by an electromagnetic radiation source of narrow or broad bandwidth, or a particle beam. The probe is stable to repeated exposure to energy in the presence of oxygen and/or other radicals.

    摘要翻译: 能够连接到一个或多个亲和分子的半导体纳米晶体化合物,包括(1)能够响应于暴露于第一能量提供第二能量的一种或多种半导体纳米晶体,和(2)一种或多种连接剂,其具有 连接到一个或多个半导体纳米晶体的第一部分和能够连接到一个或多个亲和分子的第二部分。 一种或多种连接到一个或多个亲和分子的半导体纳米晶体化合物,以形成半导体纳米晶体探针,该半导体纳米晶体探针能够与正在分析的材料中的一种或多种可检测物质结合,并且能够响应于暴露于第一能量而提供 第二个能量。 当由窄或宽带宽的电磁辐射源或粒子束激发时,探头能够发射在窄波段的电磁辐射和/或吸收,散射或衍射能量。 探针在氧和/或其他自由基存在下重复暴露于能量时是稳定的。

    Semiconductor nanocrystal probes for biological applications
    3.
    发明公开
    Semiconductor nanocrystal probes for biological applications 有权
    用于生物应用的半导体纳米晶体探针

    公开(公告)号:EP2287614A1

    公开(公告)日:2011-02-23

    申请号:EP10010743.2

    申请日:2000-02-28

    摘要: A semiconductor nanocrystal compound capable of linking to one or more affinity molecules comprising (1) one or more semiconductor nanocrystals capable of, in response to exposure to a first energy, providing a second energy, and (2) one or more linking agents, having a first portion linked to the one or more semiconductor nanocrystals and a second portion capable of linking to one or more affinity molecules. One or more of semiconductor nanocrystal compounds linked to one or more affinity molecules to form a semiconductor nanocrystal probe capable of bonding with one or more detectable substances in a material being analyzed, and are capable of, in response to exposure to a first energy, providing a second energy. The probe is capable of emitting electromagnetic radiation in a narrow wavelength band and/or absorbing, scattering, or diffracting energy when excited by an electromagnetic radiation source of narrow or broad bandwidth, or a particle beam. The probe is stable to repeated exposure to energy in the presence of oxygen and/or other radicals.

    摘要翻译: 一种能够连接到一种或多种亲和分子的半导体纳米晶体化合物,其包含(1)一种或多种半导体纳米晶体,其能够响应于暴露于第一能量而提供第二能量,和(2)一种或多种连接剂, 连接到一个或多个半导体纳米晶体的第一部分和能够连接到一个或多个亲和分子的第二部分。 一种或多种半导体纳米晶体化合物连接至一种或多种亲和分子以形成能够与待分析材料中的一种或多种可检测物质结合的半导体纳米晶体探针,并且能够响应于暴露于第一能量而提供, 第二种能量。 探头能够发射狭窄波长带中的电磁辐射和/或当被窄或宽带宽的电磁辐射源或粒子束激发时吸收,散射或衍射能量。 在存在氧气和/或其他自由基的情况下重复暴露于能量时,探针是稳定的。

    SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS
    6.
    发明公开
    SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS 审中-公开
    半导体纳米晶体生物应用探针

    公开(公告)号:EP1166118A1

    公开(公告)日:2002-01-02

    申请号:EP00915944.3

    申请日:2000-02-28

    摘要: A semiconductor nanocrystal compound capable of linking to one or more affinity molecules comprising (1) one or more semiconductor nanocrystals capable of, in response to exposure to a first energy, providing a second energy, and (2) one or more linking agents, having a first portion linked to the one or more semiconductor nanocrystals and a second portion capable of linking to one or more affinity molecules. One or more of semiconductor nanocrystal compounds linked to one or more affinity molecules to form a semiconductor nanocrystal probe capable of bonding with one or more detectable substances in a material being analyzed, and are capable of, in response to exposure to a first energy, providing a second energy. The probe is capable of emitting electromagnetic radiation in a narrow wavelength band and/or absorbing, scattering, or diffracting energy when excited by an electromagnetic radiation source of narrow or broad bandwidth, or a particle beam. The probe is stable to repeated exposure to energy in the presence of oxygen and/or other radicals.

    摘要翻译: 一种能够连接到一种或多种亲和分子的半导体纳米晶体化合物,其包含(1)一种或多种半导体纳米晶体,其能够响应于暴露于第一能量而提供第二能量,和(2)一种或多种连接剂, 连接到一个或多个半导体纳米晶体的第一部分和能够连接到一个或多个亲和分子的第二部分。 一种或多种半导体纳米晶体化合物连接至一种或多种亲和分子以形成能够与待分析材料中的一种或多种可检测物质结合的半导体纳米晶体探针,并且能够响应于暴露于第一能量而提供, 第二种能量。 探头能够发射狭窄波长带中的电磁辐射和/或当被窄或宽带宽的电磁辐射源或粒子束激发时吸收,散射或衍射能量。 在存在氧气和/或其他自由基的情况下重复暴露于能量时,探针是稳定的。