SENSING ELEMENT FOR USE WITH MEDIA-PRESERVING STORAGE AND CALIBRATION CHAMBER

    公开(公告)号:EP4339603A3

    公开(公告)日:2024-06-19

    申请号:EP24153200.1

    申请日:2018-09-21

    摘要: A single-use sensor structure, comprising: a sensor housing (1502) including a storage compartment (300, 1540) configured to retain a storage medium (322, 1542) therein, the storage compartment (300, 1540) extending between a plug (1560) located at a proximal end of the storage compartment and a sealing element (3 10b, 1512) located at a distal end of the storage compartment (300, 1540); a movable component (1504) longitudinally translatable relative to the sensor housing, the movable component (1504) comprising: a sensing surface (1522); an inactive distal portion (214) distal the sensing surface (1522); and a proximal portion proximal the sensing surface (1522), wherein the movable component (1504) is reversibly movable between a first position in which the sensing surface (1522) is located within the storage compartment (300, 1540) and the proximal portion is at least partially proximal the plug (1560) and outside the storage compartment (300, 1540) and a second position in which the sensing surface (1522) is located distal the sealing element (310b, 1512) and exposed to the exterior of the sensor housing (1502) and the proximal portion is at least partially distal the plug (1560) and inside the storage compartment (300, 1540); and a bellows structure (1570) proximal the plug (1560) and defining a sterile and compressible area which retains at least a portion of the proximal portion of the movable component therein when the movable component (1504) is in the first position.

    EINWEG-ANSCHLUSSEINRICHTUNG
    6.
    发明公开

    公开(公告)号:EP3408370A1

    公开(公告)日:2018-12-05

    申请号:EP17701548.4

    申请日:2017-01-27

    申请人: Eppendorf AG

    摘要: The invention relates to a single-use connection device (10) for inserting in a connection opening of a bioreactor, in particular in a connection opening of a top plate of a dimensionally-stable bioreactor and/or in a connection opening of a connection element of a bag bioreactor. The invention further relates to a top plate for a bioreactor and to a bioreactor for cultivating microorganisms and/or cell cultures. In addition, the invention relates to a connection element for a bag bioreactor as well as a bag bioreactor for cultivating microorganisms in cell cultures. The single-use connection device (10) is for inserting in a connection opening of a top plate of a bioreactor and/or in a connection opening of a bag bioreactor, having multiple passages (102) and an attachment section (110), characterised in that the single-use connection device (10) is formed as a single piece and is made of plastic and the attachment section (110), on an outer peripheral surface (112), has an attachment structure (114) for attaching the single-use connection device (10) in the connection opening. (Fig. 1)

    BEHÄLTER MIT EINEM MESSZELLE
    8.
    发明公开

    公开(公告)号:EP3394241A1

    公开(公告)日:2018-10-31

    申请号:EP16825763.2

    申请日:2016-12-22

    IPC分类号: C12M1/34 G01N21/03

    摘要: The invention relates to a container (1) having a measuring-cell housing (5) of an optical measuring cell (4) that protrudes into the container interior (2) of the container, wherein the measuring-cell housing (5) has a measuring gap (6), which is bounded by two lateral surfaces (8, 9) lying opposite each other at a distance (7) and by a connecting surface (10) that connects the lateral surfaces (8, 9), wherein the lateral surfaces (8, 9) each have an optical window (11, 12), and wherein at least one first optical fiber (15, 15') is arranged before the first window (11) and at least one second optical fiber (17, 17') is arranged before the second window (12). The invention is characterized in that the measuring-cell housing (5) has holding channels (14, 16, 18) arranged before the windows (11, 12, 13) for holding the at least optical fiber (15, 15', 17, 17', 19) in each case, that the holding channels (14, 16, 18) can be subsequently fitted with the optical fibers (15, 15', 17, 17', 19) from the outside, and that the measuring-cell housing (5) having the windows (11, 12, 13) and the holding channels (14, 16, 18) is fixedly connected to the wall (3) of the container interior (2).

    SINGLE-USE BIOREACTOR SENSOR INTERFACE
    9.
    发明公开

    公开(公告)号:EP3387109A1

    公开(公告)日:2018-10-17

    申请号:EP16873609.8

    申请日:2016-11-30

    发明人: FENG, Chang-Dong

    IPC分类号: C12M1/34 C12M1/12

    摘要: A bioreactor sensing system is presented. The bioreactor sensing system comprises a bioreaction vessel. The bioreaction vessel comprises an aperture configured to provide an interface for monitoring contents within the bioreaction vessel. The bioreaction vessel also comprises a port coupled to the bioreaction vessel proximate the aperture. The bioreactor sensing system also comprises a sensing device disposed at least partially within the port such that a sensing element is exposed to the contents. The bioreactor sensing system also comprises an external seal configured to be applied over a portion of the sensing device and a portion of the port.