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公开(公告)号：EP2753702A2
公开(公告)日：2014-07-16
申请号：EP12766509.9
申请日：2012-09-07
CPC分类号： C12P17/184 , C12N9/0008 , C12N9/0026 , C12N9/0071 , C12N9/1029 , C12N9/1217 , C12N9/93 , C12N15/52 , C12Y102/01041 , C12Y105/99008 , C12Y203/01 , C12Y207/02011 , C12Y603/03004 , C12Y603/04016 , C12Y603/05005 , Y02P20/52
摘要： or salts thereof; wherein , R1, R2, R3, R4, R5 and R6 are defined herein. Also provided are pharmaceutical compositions comprising a compound generated by the inventive cell-free system, and use of these compounds and compositions for the treatment of bacterial infections.
摘要翻译： 或其盐; 其中，R1，R2，R3，R4，R5和R6如本文所定义。 还提供了包含由本发明的无细胞系统产生的化合物的药物组合物，以及这些化合物和组合物用于治疗细菌感染的用途。
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2.发明公开MICROORGANISM WITH IMPROVED PRODUCTION OF 5'-XANTHOSINE MONOPHOSPHATE AND 5'-GUANINE MONOPHOSPHATE, AND PRODUCTION METHOD OF 5'-XANTHOSINE MONOPHOSPHATE AND 5'-GUANINE MONOPHOSPHATE USING SAME 有权MONO和磷酸盐生产5'-磷酸和黄苷5'-单磷酸鸟嘌呤SO - 与5“磷酸黄嘌呤核苷和5'-鸟嘌呤提高了生产微生物
公开(公告)号：EP2548949A2
公开(公告)日：2013-01-23
申请号：EP11756570.5
申请日：2011-03-17
发明人： CHO, Jin Man , LEE, Jin Nam , KIM, Hye Won , LEE, Ji Hye , YOON, Nan Young , LEE, Kwang Woo , OH, Yoon Seok , PARK, Jang Hee
CPC分类号： C12N15/77 , C12N9/0026 , C12P19/32 , C12Y105/99008 , Y02P20/582
摘要： The present invention relates to a microorganism with improved production of 5'-xanthosine monophosphate and 5'-guanine monophosphate, and more specifically, to a Corynebacterium sp. microorganism having increased proline dehydrogenase activity compared with an intrinsic activity thereof, a method for producing 5'-xanthosine monophosphate or 5'-guanine monophosphate from the culture medium obtained by culturing the transformed microorganism, and a use of the microorganism for production of 5'-xanthosine monophosphate or 5'-guanine monophosphate.
摘要翻译： 本发明涉及具有改进的生产5'-黄苷单磷酸酯和5'-鸟嘌呤单磷酸，并且更具体的微生物，在棒状杆菌属。 微生物具有增加的脯氨酸脱氢酶活性与内在活性，其用于制造5的方法“从通过培养转化的微生物得到的培养介质黄苷单磷酸或5'-单磷酸鸟嘌呤，和用于生产的5使用该微生物的”相比 -xanthosine单磷酸或5'-鸟嘌呤单磷酸。
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3.发明授权MICROORGANISM WITH IMPROVED PRODUCTION OF 5'-XANTHOSINE MONOPHOSPHATE AND 5'-GUANINE MONOPHOSPHATE, AND PRODUCTION METHOD OF 5'-XANTHOSINE MONOPHOSPHATE AND 5'-GUANINE MONOPHOSPHATE USING SAME 有权提高5'-单硫代磷酸鸟苷和5'-鸟苷单磷酸生产的微生物以及使用相同方法生产5'-单硫代磷酸核苷和5'-鸟苷单磷酸的方法
公开(公告)号：EP2548949B1
公开(公告)日：2017-07-26
申请号：EP11756570.5
申请日：2011-03-17
发明人： CHO, Jin Man , LEE, Jin Nam , KIM, Hye Won , LEE, Ji Hye , YOON, Nan Young , LEE, Kwang Woo , OH, Yoon Seok , PARK, Jang Hee
CPC分类号： C12N15/77 , C12N9/0026 , C12P19/32 , C12Y105/99008 , Y02P20/582
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4.发明公开MICROORGANISM WITH IMPROVED PRODUCTION OF 5'-XANTHOSINE MONOPHOSPHATE AND 5'-GUANINE MONOPHOSPHATE, AND PRODUCTION METHOD OF 5'-XANTHOSINE MONOPHOSPHATE AND 5'-GUANINE MONOPHOSPHATE USING SAME 有权MONO和磷酸盐生产5'-磷酸和黄苷5'-单磷酸鸟嘌呤SO - 与5“磷酸黄嘌呤核苷和5'-鸟嘌呤提高了生产微生物
公开(公告)号：EP2548949A4
公开(公告)日：2013-08-21
申请号：EP11756570
申请日：2011-03-17
申请人： CJ CHEILJEDANG CORP
发明人： CHO JIN MAN , LEE JIN NAM , KIM HYE WON , LEE JI HYE , YOON NAN YOUNG , LEE KWANG WOO , OH YOON SEOK , PARK JANG HEE
CPC分类号： C12N15/77 , C12N9/0026 , C12P19/32 , C12Y105/99008 , Y02P20/582
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