公开(公告)号：EP3116392A4

公开(公告)日：2018-02-14

申请号：EP15762394

申请日：2015-03-16

申请人： RHODE ISLAND HOSPITAL

发明人： CHEN QIAN ,  CHEN YUPENG ,  YU HONGCHUAN ,  EHRLICH MICHAEL G

IPC分类号： A61K47/69 ,  A61K9/51 ,  C12N15/113

CPC分类号： A61K31/519 ,  A61K9/0019 ,  A61K9/0092 ,  A61K9/08 ,  A61K9/5123 ,  A61K9/5146 ,  A61K47/6949 ,  A61K49/0095 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/1138 ,  C12N2310/14 ,  C12N2320/32 ,  C12Q1/6881 ,  C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/158 ,  C12Q2600/178 ,  C12Y304/24812 ,  G01N33/6893 ,  G01N2800/102

摘要： The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis.

公开(公告)号：EP3116392A2

公开(公告)日：2017-01-18

申请号：EP15762394.3

申请日：2015-03-16

申请人： Rhode Island Hospital

发明人： CHEN, Qian ,  CHEN, Yupeng ,  YU, Hongchuan ,  EHRLICH, Michael, G.

IPC分类号： A61B5/055 ,  A01N25/00 ,  A61K47/00

CPC分类号： A61K31/519 ,  A61K9/0019 ,  A61K9/0092 ,  A61K9/08 ,  A61K9/5123 ,  A61K9/5146 ,  A61K47/6949 ,  A61K49/0095 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/1138 ,  C12N2310/14 ,  C12N2320/32 ,  C12Q1/6881 ,  C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/158 ,  C12Q2600/178 ,  C12Y304/24812 ,  G01N33/6893 ,  G01N2800/102

摘要： The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis.

摘要翻译： 本发明的组合物和方法提供组合物优先靶向给递送治疗剂或诊断剂的组合物和方法。 例如，这样的化合物可用于治疗影响关节关节的关节疾病，例如损伤诱发的骨关节炎以及影响关节组织如类风湿性关节炎的自身免疫性疾病。