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    ARTIFICIAL DURA MATER AND MANUFACTURING METHOD THEREOF
    4.
    发明公开
    ARTIFICIAL DURA MATER AND MANUFACTURING METHOD THEREOF 有权
    赫尔辛基·杜拉（DUA）MATER UND HERSTELLUNGSVERFAHRENDAFÜR

    公开(公告)号：EP2340785A1

    公开(公告)日：2011-07-06

    申请号：EP10750329.4

    申请日：2010-02-08

    申请人： Medprin Regenerative Medical Technologies Co., Ltd

    发明人： XU, Tao ,  YUAN, Yuyu

    IPC分类号： A61F2/02 ,  A61L27/20 ,  A61L27/24 ,  A61L27/54 ,  A61L31/06 ,  D01D5/00

    CPC分类号： A61F2/02 ,  A61L27/14 ,  A61L27/18 ,  A61L27/26 ,  A61L27/50 ,  A61L27/52 ,  A61L27/54 ,  A61L27/58 ,  B32B5/26 ,  B32B2250/20 ,  B32B2307/7163 ,  B32B2307/728 ,  B32B2307/73 ,  B32B2535/00 ,  D01D5/003 ,  D04H1/435 ,  D04H1/72 ,  D04H1/728 ,  D04H3/005 ,  D04H3/009 ,  D04H3/011 ,  D04H3/02 ,  D04H3/073

    摘要： Disclosed are an artificial dura and its manufacturing method. The artificial dura mater consists of an electrospun layer by electrospinning. The electrospun layer has at least a hydrophobic electrospun layer. And there is at least a hydrophilic electrospun layer on the hydrophobic electrospun layer. A transition layer is formed between the hydrophobic electrospun layer and the hydrophilic electrospun layer. Cytokine and/or medicine can be added with every layer of the artificial dura mater, furthermore, can be adhered to the hydrophobic electrospun layer and/or the hydrophilic electrospun layer by bio-printing technique. The dura mater has a characteristic of good biocompatibility, accelerating the regeneration process of its tissue, excellent repairing effect, anti-adhesion, complete absorption, good mechanical properties, low infection rate, and capability of adding other therapeutic substances.

    摘要翻译： 公开了人造硬膜及其制造方法。 人造硬脑膜由静电纺丝层组成。 电纺层至少具有疏水性电纺丝层。 并且在疏水性电纺丝层上至少有一个亲水的电纺丝层。 在疏水性电纺丝层和亲水性电纺丝层之间形成过渡层。 细胞因子和/或药物可以与人造硬膜的每一层相加，此外，可以通过生物印刷技术粘附到疏水性电纺丝层和/或亲水性电纺丝层。 硬脑膜具有生物相容性好，加速组织再生过程，修复效果好，抗粘连，吸收全，机械性能好，感染率低，加入其他治疗物质的能力。

    Process for producing tubular shaped fibrous articles
    5.
    发明公开
    Process for producing tubular shaped fibrous articles 失效
    制造管状纤维制品的方法

    公开(公告)号：EP0242642A3

    公开(公告)日：1990-08-08

    申请号：EP87104760.1

    申请日：1987-03-31

    申请人： Chisso Corporation

    发明人： Goi, Shigeru ,  Sugihara, Taizo ,  Sonoda, Hiroshi

    IPC分类号： D04H1/00 ,  D04H3/07

    CPC分类号： D04H3/14 ,  D04H3/073

    摘要： In a process for producing tubular shaped fibrous articles of small diameter by heating and cooling a fibrous bundle containing at least 20 weight % of hot-melt-adhesive composite fibers, the improvements comprise using a shaping apparatus including an injecting chamber (1), an injecting hole (2) formed in the wall of the chamber, a fibrous bundle outlet (5) provided with a nozzle of a desired shape in cross-section, a cylindrical pipe (6) for introducing the fibrous bundle, which has a cross-sectional area larger than that of said outlet, is located at a position opposite to the outlet and projects toward the outlet and terminates in the injecting chamber, and a core pipe (7) which is open at its base on the outside of the injecting chamber, has its one end inserted through the cylindrical pipe and extending into the nozzle through the injecting chamber, and having a vent (8) in its portion exposed within the injecting chamber, and passing the fibrous bundle through the cylindrical pipe to the outlet, while injecting a hot compressed gas through the injecting hole, thereby to heat and shape the fibrous bundle to and at its hot-melt-adhesive temperature.