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公开(公告)号：EP3396430A1
公开(公告)日：2018-10-31
申请号：EP17400019.0
申请日：2017-04-27
CPC分类号： G02B21/367 , G02B21/242 , G02B21/244 , G02B21/245
摘要： It is provided a method for optical scanning of at least one object region (105) placed on a transparent specimen holder (107), the method comprising: for each sample lateral position (x1) of plural predefined sample lateral positions (x0,x1,x2) performing a focus determination by: performing laser reflection and using a first camera (109) taking plural first images to determine a reference distance (rd) between the specimen holder (107) and an objective lens (113); performing transmission flash illumination and using a second camera (111) taking plural second images to define a focus distance taking into account the reference distance (rd); after completing the focus determination, determining a focus distance topology (600; 700) across the object region (105) based on the focus distances determined for all sample lateral positions (x0,x1,x2); and laterally moving the specimen holder (107) and acquiring third images while focusing according to the focus distance topology (600, 700);
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公开(公告)号：EP3204814A1
公开(公告)日：2017-08-16
申请号：EP14786635.4
申请日：2014-10-06
发明人： SEE, Seng, Ho
IPC分类号： G02B21/26
CPC分类号： G02B21/241 , G02B21/242 , G02B21/26
摘要： The invention relates to a microscope (10) having a movable stage (18) and an adjusting unit (24) for moving the stage (18). The adjusting unit (24) comprises a drive shaft (38) by the rotation of which the distance between the stage (18) and a base (22) of the microscope (10) is adjustable. Further, the microscope (10) has a manually operable operating unit (26) with a first output shaft (46) as well as an electric drive unit (28) for the motorized movement of the stage (18) with a second output shaft (52). In a manual operating mode, the drive shaft (38) is coupled to the first output shaft (46) via a first coupling unit (54), and in a motorized operating mode the drive shaft (38) is coupled to the second output shaft (52) via a second coupling unit (56).
摘要翻译： 本发明涉及一种具有可移动台（18）和用于移动台（18）的调节单元（24）的显微镜（10）。 调节单元（24）包括驱动轴（38），通过该驱动轴的旋转，台架（18）和显微镜（10）的基座（22）之间的距离可调节。 此外，显微镜（10）具有带第一输出轴（46）的可手动操作的操作单元（26）以及用于台（18）的机动移动的电驱动单元（28），第二输出轴 52）。 在手动操作模式中，驱动轴（38）经由第一联接单元（54）联接至第一输出轴（46），并且在机动操作模式中，驱动轴（38）联接至第二输出轴 （52）经由第二联接单元（56）。
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公开(公告)号：EP3014328A4
公开(公告)日：2017-01-18
申请号：EP14818344
申请日：2014-06-27
申请人： ECHO LABORATORIES
发明人： CHO EUGENE L , TALBOT RYAN P , GEMMEN GREGORY J , GARCIA ERIC R
CPC分类号： G02B21/0088 , G02B21/02 , G02B21/086 , G02B21/24 , G02B21/241 , G02B21/242 , G02B21/26 , G02B21/34 , G02B21/362 , G02B21/368 , Y10T29/49002
摘要： A dual-configuration microscope is provided. The microscope may be converted into an upright configuration or an inverted configuration. The microscope includes a base having a lower portion and an upper portion, the lower portion configured to support the microscope. The microscope further includes a body having a first portion, a second portion, and an intermediate portion extending between the first and second portions. The intermediate portion of the body is rotatably coupled to the upper portion of the base at a rotational coupling. The rotational coupling defines a rotating axis that extends in a longitudinal direction with respect to the microscope. The microscope further includes an objective disposed proximal to the first portion and a light source disposed proximal to the second portion.
摘要翻译： 提供双重配置显微镜。 显微镜可以转换为直立构型或倒置配置。 显微镜包括具有下部和上部的基部，下部构造成支撑显微镜。 显微镜还包括具有第一部分，第二部分和在第一和第二部分之间延伸的中间部分的主体。 主体的中间部分以旋转联接可旋转地联接到基座的上部。 旋转联接器限定了相对于显微镜在纵向方向上延伸的旋转轴线。 显微镜还包括设置在第一部分附近的物体和靠近第二部分设置的光源。
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4.发明公开
公开(公告)号：EP1988417A1
公开(公告)日：2008-11-05
申请号：EP08008379.3
申请日：2008-05-02
申请人： Olympus Corporation
CPC分类号： G02B21/0088 , G02B21/242 , G02B21/34
摘要： This is an optical apparatus provided with an objective (5) with a correction collar (5A) for correcting aberration due to an error in the optical thickness of a cover glass (20) comprising a focusing mechanism for changing a distance between the objective (5) and the sample (18), an optical thickness detecting unit for detecting the optical thickness of the cover glass (20), an operating unit (27) for calculating the amount of aberration correction, based on the optical thickness of the cover glass detected by the optical thickness detecting unit, a driver unit (25) for driving a correction collar, based on the amount of aberration correction calculated by the operating unit (27) and an imaging sensor (15) for forming the image of the sample that passes through the objective.
摘要翻译： 这是一种具有目标（5）的光学装置，其具有用于校正由于玻璃（20）的光学厚度的误差引起的像差的校正环（5A），所述遮盖玻璃包括用于改变物镜（5）之间的距离的聚焦机构 ）和样品（18），用于检测盖玻璃（20）的光学厚度的光学厚度检测单元，用于根据检测到的盖玻璃的光学厚度计算像差校正量的操作单元（27） 通过光学厚度检测单元，基于由操作单元（27）计算的像差校正量和用于形成通过的样本图像的成像传感器（15），驱动校正环的驱动单元（25） 通过目标。
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5.发明公开
公开(公告)号：EP0139967A3
公开(公告)日：1985-06-12
申请号：EP84109859
申请日：1984-08-18
发明人： Muth, Karl-Heinz
CPC分类号： G01N29/0681 , G02B21/0088 , G02B21/242
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公开(公告)号：EP2740002A1
公开(公告)日：2014-06-11
申请号：EP12731011.8
申请日：2012-07-05
发明人： MARTH, Harry
IPC分类号： G02B21/24
CPC分类号： G02B7/04 , G02B21/242 , G02B21/244
摘要： The invention relates to a method and to an arrangement for operating a dynamic nano focusing system for use thereof in the field of microscopy, interferometry or similar applications, wherein the nano focusing system comprises a lever-transmission piezo actuator and a frictionless guide based on a resiliently deformable solid body joint which is connected to a mounting unit, in particular for a lens, in order to implement the desired adjustment paths for the focusing. According to the invention, in order to increase the dynamics during the focusing process, a secondary fine adjustment movement is superimposed on the primary adjustment movement, said secondary fine adjustment movement having a smaller adjustment path but higher frequency than the primary adjustment movement, wherein, when the fine adjustment is carried out, a determination is made as to whether the focusing result changes, in order to specify according thereto the amount and/or the direction of the primary adjustment movement.
摘要翻译： 本发明涉及用于操作在显微镜，干涉测量或类似应用领域中使用的动态纳米聚焦系统的方法和装置，其中纳米聚焦系统包括杠杆传输压电致动器和基于 可弹性变形的固体接头，其连接到安装单元，特别是用于透镜，以便实现用于聚焦的期望的调节路径。 根据本发明，为了在聚焦过程中增加动态，二次微调运动叠加在主调节运动上，所述二次微调运动具有比初次调节运动更小的调节路径但频率更高的频率， 当执行微调时，确定聚焦结果是否改变，以便根据其指定一次调节运动的量和/或方向。
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公开(公告)号：EP2673671A1
公开(公告)日：2013-12-18
申请号：EP12703782.8
申请日：2012-02-08
发明人： KRUEGER, Ralf , BAUER, Tobias
CPC分类号： G02B21/06 , G02B21/006 , G02B21/242 , G02B21/244 , G02B21/245 , G03B13/36 , G03F9/7026
摘要： The invention relates to an autofocusing method for use in the microscopic examination of an object (3) lying in the focus of a microscope objective (2) of a microscope (1), using an autofocus beam path (4), wherein the autofocus beam path (4) is directed toward the microscope objective (2) by means of a deflecting device (5) arranged on the side of the microscope objective facing away from the object and from there to a reflective autofocus interface (7) in the object region, and the autofocus beam path (4) reflected on the autofocus interface (7) is directed toward an autofocus detector (9) by means of the microscope objective (2) and the deflecting device (5), wherein the deflecting device (5) has two regions (51, 52; 53, 54), which are arranged at a distance from each other in the propagation direction of the autofocus beam path (4) and which each reflect the autofocus beam path (4), for producing interfering sub-beams (41, 42, 43, 44) of the autofocus beam path (4), and wherein the autofocus detector (9) is arranged in a plane conjugate to that of the microscope objective aperture in order to detect an interference pattern produced there, wherein the focus of the microscope (1) is adjusted according to the detected interference pattern (10).
摘要翻译： 用于在显微镜物镜的焦点处的样本的显微镜检查中自动聚焦的方法使用自动聚焦光束路径，通过布置在远离样本的显微镜物镜的侧面上的偏转装置将自动聚焦光束路径引向 显微镜物镜，并从那里到样品区域的反射自动对焦界面。 自动聚焦光束路径在自动对焦界面处反射并经由显微镜物镜和偏转装置朝自动对焦检测器定向。 偏转装置包括在自动聚焦光束路径的传播方向上彼此间隔开的两个区域。 每个区域反映自动聚焦光束路径。 自动对焦检测器布置在与显微镜物镜光瞳共轭的平面中以获得干涉图案。 根据获得的干涉图案调整显微镜的焦点。
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公开(公告)号：EP1686406A3
公开(公告)日：2012-06-27
申请号：EP06000304.3
申请日：2006-01-09
申请人： Olympus Corporation
发明人： Kawanabe, Hideyuki
CPC分类号： G02B21/242 , G02B21/244
摘要： A controller (2) controls a driving speed used when a distance is changed by driving an electric focusing mechanism (10) for adjusting the distance between a sample (S) as an observation target of a microscope (1) and an objective lens (13) based on a depth of focus of an optical observation system of the microscope (1).
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9.发明公开
公开(公告)号：EP1657581A1
公开(公告)日：2006-05-17
申请号：EP05024221.3
申请日：2005-11-07
申请人： Olympus Corporation
发明人： Tsuyuki, Kei
CPC分类号： G02B7/08 , G02B21/242
摘要： A specimen and an objective lens can be quickly brought close together or separated without an operator being concerned about the positional relationship between the specimen and the objective lens, and once the correct positional relationship is established, the focal position can be finely adjusted. The invention includes a first focusing mechanism for moving the objective lens in an optical axis direction relative to the specimen so as to approach the specimen or withdraw therefrom; a second focusing mechanism for displacing an internal optical system in the optical axis direction, and a switching device for switching between operating the first focusing mechanism and operating the second focusing mechanism when the objective lens is disposed at a predetermined switching position.
摘要翻译： 样本和物镜可以快速地靠近在一起或分离，而不需要操作者关心样本和物镜之间的位置关系，并且一旦建立了正确的位置关系，就可以精细地调整焦点位置。 本发明包括：第一聚焦机构，用于相对于样品沿光轴方向移动物镜，以接近样品或从样品中取出; 用于使内部光学系统沿光轴方向移位的第二聚焦机构，以及当物镜设置在预定切换位置时，在操作第一聚焦机构和操作第二聚焦机构之间进行切换的切换装置。
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公开(公告)号：EP1418455A4
公开(公告)日：2005-07-27
申请号：EP02736091
申请日：2002-06-13
发明人： KINOSHITA KAZUHIKO , SHIO MEGUMI
CPC分类号： G02B21/242
摘要： An optical microscope of high stability such that the image of a sample does not become unsharp during observation, and no movement (drift) of an object point (object) occurs. The optical microscope is characterized by comprising vertical straight movement guide mechanisms (4 and 8) for an objective lens (6) of the microscope symmetrical to the optical axis, and fine adjustment means (10, 11 and 12) for the objective lens.
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